5-[[(1R,2S)-2-aminocyclohexyl]amino]-3-[(4,6-dimethylpyridin-2-yl)amino]pyridine-2-carboxamide

4-(4-(5-chloro-4-(2-(propylsulfonyl)phenylamino)pyrimidin-2-ylamino)-3-methoxyphenyl)-N-methylpiperazine-1-carboxamide

2-(5-bromo-2-(2,3-dihydro-1H-inden-4-ylamino)pyrimidin-4-ylamino)-N-methylbenzenesulfonamide

(S)-4-(6-(3-methylpiperazin-1-yl)pyridin-3-yl)-N-(3,4,5-trimethoxyphenyl)pyrimidin-2-amine

4-(4-(5-chloro-4-(2-(propylsulfonyl)phenylamino)pyrimidin-2-ylamino)-3-methoxyphenyl)-N,N-dimethylpiperazine-1-carboxamide

5-((1S,2R)-2-Aminocyclohexylamino)-7-(3,5-dimethoxyphenylamino)-2-phenylimidazo[1,2-c]pyrimidine-8-carboxamide

(2E)-3-{4-[({8-carbamoyl-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidin-5-yl}amino)methyl]phenyl}prop-2-enoic acid

2-(5-chloro-2-(4-(3-(dimethylamino)-2,2-dimethylpropoxy)-2-methoxyphenylamino)pyrimidin-4-ylamino)-N-isopropylbenzenesulfonamide

(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one

2-(5-bromo-2-(3-(dimethylamino)-2-methylphenylamino)pyrimidin-4-ylamino)-N-methylbenzenesulfonamide

2-(5-bromo-2-(2-methoxy-4-(2-methyl-1H-imidazol-1-yl)phenylamino)pyrimidin-4-ylamino)-N-methylbenzenesulfonamide

ethyl (2E)-3-{4-[({8-carbamoyl-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidin-5-yl}amino)methyl]phenyl}prop-2-enoate

1-(4-(5-chloro-4-(2-(propylsulfonyl)phenylamino)pyrimidin-2-ylamino)-3-methoxyphenyl)piperidine-4-carboxamide

5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethoxyphenylamino)-[1,2,4]triazolo[4,3-c]pyrimidine-8-carboxamide

2-(5-chloro-2-(4-(3-(ethylamino)pyrrolidin-1-yl)-2-methoxyphenylamino)pyrimidin-4-ylamino)-N-isopropylbenzenesulfonamide

5-{[(2,4-difluorophenyl)methyl]amino}-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidine-8-carboxamide

7-[(3,5-dimethoxyphenyl)amino]-5-{[(4-sulfamoylphenyl)methyl]amino}imidazo[1,2-a]pyrimidine-8-carboxamide

5-(2-Amino-2-methylpropylamino)-7-(3,5-dimethoxyphenylamino)-2-phenylimidazo[1,2-c]pyrimidine-8-carboxamide

2-(5-chloro-2-(4-(3-(dimethylamino)pyrrolidin-1-yl)-2-methoxyphenylamino)pyrimidin-4-ylamino)-N-isopropylbenzenesulfonamide

4-[({8-carbamoyl-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidin-5-yl}amino)methyl]benzoic acid

7-[(3,5-dimethoxyphenyl)amino]-5-{[(4-methanesulfonylphenyl)methyl]amino}imidazo[1,2-a]pyrimidine-8-carboxamide

5-[(1H-1,3-benzodiazol-2-ylmethyl)amino]-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidine-8-carboxamide

1-(4-(5-bromo-4-(2-(N-methylsulfamoyl)phenylamino)pyrimidin-2-ylamino)-3-methoxyphenyl)piperidine-3-carboxamide

7-[(3,5-dimethoxyphenyl)amino]-5-{[(4-fluorophenyl)methyl]amino}imidazo[1,2-a]pyrimidine-8-carboxamide

7-[(3,5-dimethoxyphenyl)amino]-5-{[(4-methoxyphenyl)methyl]amino}imidazo[1,2-a]pyrimidine-8-carboxamide

5-[[(1S,2R)-2-aminocyclohexyl]amino]-7-(3,5-dimethoxyanilino)imidazo[1,2-c]pyrimidine-8-carboxamide

2-{4-[({8-carbamoyl-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidin-5-yl}amino)methyl]phenyl}acetic acid

7-[(3,5-dimethoxyphenyl)amino]-5-[(pyridin-4-ylmethyl)amino]imidazo[1,2-a]pyrimidine-8-carboxamide

5-chloro-N2-(2-methoxy-4-morpholinophenyl)-N4-(2-(methylsulfonyl)phenyl)pyrimidine-2,4-diamine

2-(5-chloro-2-(2-methoxy-4-((1-methylpiperidin-3-yl)methoxy)phenylamino)pyrimidin-4-ylamino)-N-isopropylbenzenesulfonamide

5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethoxyphenylamino)-[1,2,4]triazolo[1,5-c]pyrimidine-8-carboxamide

7-[(3,5-dimethoxyphenyl)amino]-5-{[(2-methoxyphenyl)methyl]amino}imidazo[1,2-a]pyrimidine-8-carboxamide

5-(benzylamino)-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidine-8-carboxamide

N-[1-[4-[[5-chloro-4-[2-(propan-2-ylsulfamoyl)anilino]pyrimidin-2-yl]amino]-3-methoxyphenyl]pyrrolidin-3-yl]-N-methylacetamide

7-[(3,5-dimethoxyphenyl)amino]-5-{[(1R)-1-phenylethyl]amino}imidazo[1,2-a]pyrimidine-8-carboxamide

imidazo[1,2-c]pyrimidine-8-carboxamide, 10t

5-({[4-(carbamoylmethyl)phenyl]methyl}amino)-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidine-8-carboxamide

5-[[(1S,2R)-2-aminocyclohexyl]amino]-7-(3,5-dimethylanilino)imidazo[1,2-c]pyrimidine-8-carboxamide

7-[(3,5-dimethoxyphenyl)amino]-5-{[(3-methoxyphenyl)methyl]amino}imidazo[1,2-a]pyrimidine-8-carboxamide

2-(5-bromo-2-(4,4'-dimethoxybiphenyl-3-ylamino)pyrimidin-4-ylamino)-N-methylbenzenesulfonamide

5-((1R,2S)-2-Aminocyclohexylamino)-7-(3,5-dimethoxyphenylamino)-2-phenylimidazo[1,2-c]pyrimidine-8-carboxamide

5-{[(4-carbamoylphenyl)methyl]amino}-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidine-8-carboxamide

7-[(3,5-dimethoxyphenyl)amino]-5-({[4-(hydroxymethyl)phenyl]methyl}amino)imidazo[1,2-a]pyrimidine-8-carboxamide

(R)-1-(4-(5-chloro-4-(2-(methylcarbamoyl)phenylamino)pyrimidin-2-ylamino)-3-methoxyphenyl)piperidine-3-carboxamide

5-[[(1S,2R)-2-aminocyclohexyl]amino]-7-(3,5-difluoroanilino)imidazo[1,2-c]pyrimidine-8-carboxamide

5-{[(3,5-difluorophenyl)methyl]amino}-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidine-8-carboxamide

7-[(3,5-dimethoxyphenyl)amino]-5-[(furan-2-ylmethyl)amino]imidazo[1,2-a]pyrimidine-8-carboxamide

7-[(3,5-dimethoxyphenyl)amino]-5-{[(1S)-1-phenylethyl]amino}imidazo[1,2-a]pyrimidine-8-carboxamide

2-(5-bromo-2-(2,4-dimethoxyphenylamino)pyrimidin-4-ylamino)-N-methylbenzenesulfonamide

5-[[(1S,2R)-2-aminocyclohexyl]amino]-7-(3-methoxyanilino)imidazo[1,2-c]pyrimidine-8-carboxamide

2-(2-(1H-indazol-7-ylamino)-5-bromopyrimidin-4-ylamino)-N-methylbenzenesulfonamide

7-(3,5-dimethoxyanilino)-5-[[(1S,2R)-2-hydroxycyclohexyl]amino]imidazo[1,2-c]pyrimidine-8-carboxamide

2-(5-bromo-2-(2,4-difluorophenylamino)pyrimidin-4-ylamino)-N-methylbenzenesulfonamide

7-[(3,5-dimethoxyphenyl)amino]-5-[(2-hydroxyethyl)amino]imidazo[1,2-a]pyrimidine-8-carboxamide

5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-(4-(methylamino)piperidin-1-yl)phenyl)pyrimidine-2,4-diamine

7-[(3,5-dimethoxyphenyl)amino]-5-(methylsulfanyl)imidazo[1,2-a]pyrimidine-8-carboxamide

5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(2-methoxy-4-nitrophenyl)pyrimidine-2,4-diamine

2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)pyrimidin-4-ylamino)-N-cyclopentylbenzenesulfonamide

imidazo[1,2-c]pyrimidine-8-carboxamide, 20

7-(3,5-Dimethoxyphenylamino)-5-(2-methylcyclohexylamino)imidazo[1,2-c]pyrimidine-8-carboxamide

5-[(2-aminoethyl)amino]-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidine-8-carboxamide

1,2,4-Oxadiazole Analogue 12d

5-[[(1S,2R)-2-aminocyclohexyl]amino]-7-(4-methoxyanilino)imidazo[1,2-c]pyrimidine-8-carboxamide

7-[(3,5-dimethoxyphenyl)amino]-5-[(2-phenylethyl)amino]imidazo[1,2-a]pyrimidine-8-carboxamide

2-(2-aminoethylamino)-4-(m-tolylamino)pyrimidine-5-carboxamide

5-[benzyl(methyl)amino]-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidine-8-carboxamide

2-(2-aminoethylamino)-4-(p-tolylamino)pyrimidine-5-carboxamide

3-(5-((5-chloro-2-oxoindolin-3-ylidene)methyl)-4-methyl-1H-pyrrol-3-yl)propanoic acid

2-(2-aminoethylamino)-4-(3-cyanophenylamino)pyrimidine-5-carboxamide

5-amino-7-[(3,5-dimethoxyphenyl)amino]imidazo[1,2-a]pyrimidine-8-carboxamide

5-[[(1S,2S)-2-aminocyclohexyl]amino]-7-(3,5-dimethoxyanilino)imidazo[1,2-c]pyrimidine-8-carboxamide

5-[[(1S,2R)-2-aminocyclohexyl]amino]-7-(2-methoxyanilino)imidazo[1,2-c]pyrimidine-8-carboxamide

2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)pyrimidin-4-ylamino)-4,5-difluoro-N-methylbenzamide

5-(3-Aminopropylamino)-7-(3,5-dimethoxyphenylamino)imidazo[1,2-c]pyrimidine-8-carboxamide

2-(2-aminoethylamino)-4-(phenylamino)pyrimidine-5-carboxamide

(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one

3-(4-methyl-5-{[(3Z)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid

(Z)-3-[2,4-dimethyl-5-(2-oxo-1,2-dihydro-indol-3-ylidenemethyl)-1H-pyrrol-3-yl]-propionic acid

3,10,13,16,23-pentaazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(23),2,4(9),5,7,11(15),17(22),18,20-nonaen-12-one

3-(2,2-difluoro-10,12-dimethyl-1-aza-3-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-3,5,7,9,11-pentaen-4-yl)-N-[2-[2-[2-[2-[[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]amino]ethoxy]ethoxy]ethoxy]ethyl]propanamide