General Information of the Compound
| Compound ID |
CP0444648
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| Compound Name |
5-(2-Amino-2-methylpropylamino)-7-(3,5-dimethoxyphenylamino)-2-phenylimidazo[1,2-c]pyrimidine-8-carboxamide
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| Structure |
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| Formula |
C25H29N7O3
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| Molecular Weight |
475.553
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| Canonical SMILES |
COc1cc(Nc2nc(NCC(C)(C)N)n3cc(nc3c2C(N)=O)-c2ccccc2)cc(OC)c1
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| InChI |
InChI=1S/C25H29N7O3/c1-25(2,27)14-28-24-31-22(29-16-10-17(34-3)12-18(11-16)35-4)20(21(26)33)23-30-19(13-32(23)24)15-8-6-5-7-9-15/h5-13,29H,14,27H2,1-4H3,(H2,26,33)(H,28,31)
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| InChIKey |
VTOIZTHVLKSUOX-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01441, Tyrosine-protein kinase SYK
Protein ID: PT00846, Tyrosine-protein kinase ZAP-70