General Information of the Compound
| Compound ID |
CP0441429
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| Compound Name |
5-(3-Aminopropylamino)-7-(3,5-dimethoxyphenylamino)imidazo[1,2-c]pyrimidine-8-carboxamide
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| Structure |
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| Formula |
C18H23N7O3
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| Molecular Weight |
385.428
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| Canonical SMILES |
COc1cc(Nc2nc(NCCCN)n3ccnc3c2C(N)=O)cc(OC)c1
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| InChI |
InChI=1S/C18H23N7O3/c1-27-12-8-11(9-13(10-12)28-2)23-16-14(15(20)26)17-21-6-7-25(17)18(24-16)22-5-3-4-19/h6-10,23H,3-5,19H2,1-2H3,(H2,20,26)(H,22,24)
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| InChIKey |
IMQAXTSZPBVLKY-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01441, Tyrosine-protein kinase SYK
Protein ID: PT00846, Tyrosine-protein kinase ZAP-70