| Compound ID |
Compound Name |
Compound Formula |
|
CP0376695
|
N-[[4-[5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)imidazo[4,5-b]pyridin-3-yl]phenyl]methyl]-3-fluorobenzamide
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|
C33H26FN7O2
|
3
|
| 1 |
IC50 = 44 nM
|
|
|
| 2 |
IC50 = 45 nM
|
|
|
| 3 |
IC50 = 220 nM
|
|
|
|
CP0405066
|
N-[[4-[2-(2-aminopyridin-3-yl)-6-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]-3-fluorobenzamide
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|
C30H22FN7O
|
3
|
| 1 |
IC50 = 46 nM
|
|
|
| 2 |
IC50 = 49 nM
|
|
|
| 3 |
IC50 = 820 nM
|
|
|
|
CP0389476
|
2-[4-[5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)imidazo[4,5-b]pyridin-3-yl]phenyl]-N-phenylacetamide
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|
C33H27N7O2
|
3
|
| 1 |
IC50 = 47 nM
|
|
|
| 2 |
IC50 = 49 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0453697
|
2-[4-[2-(2-aminopyridin-3-yl)-5-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl]phenyl]-N-phenylacetamide
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|
C30H23N7O
|
3
|
| 1 |
IC50 = 51 nM
|
|
|
| 2 |
IC50 = 69 nM
|
|
|
| 3 |
IC50 = 2500 nM
|
|
|
|
CP0441192
|
N-[[4-[2-(2-aminopyridin-3-yl)-6-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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|
C30H23N7O
|
3
|
| 1 |
IC50 = 80 nM
|
|
|
| 2 |
IC50 = 91 nM
|
|
|
| 3 |
IC50 = 1500 nM
|
|
|
|
CP0397465
|
2-[4-[5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)imidazo[4,5-b]pyridin-3-yl]phenyl]-N-(3-fluorophenyl)acetamide
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|
C33H26FN7O2
|
3
|
| 1 |
IC50 = 90 nM
|
|
|
| 2 |
IC50 = 260 nM
|
|
|
| 3 |
IC50 = 1500 nM
|
|
|
|
CP0376644
|
N-[[4-[2-(2-aminopyridin-3-yl)-5-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]-3-fluorobenzamide
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|
C30H22FN7O
|
3
|
| 1 |
IC50 = 95 nM
|
|
|
| 2 |
IC50 = 340 nM
|
|
|
| 3 |
IC50 = 2100 nM
|
|
|
|
CP0376692
|
N-[[4-[5-(3-acetamidophenyl)-2-(2-aminopyridin-3-yl)imidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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|
C33H27N7O2
|
3
|
| 1 |
IC50 = 110 nM
|
|
|
| 2 |
IC50 = 170 nM
|
|
|
| 3 |
IC50 = 840 nM
|
|
|
|
CP0441194
|
N-[[4-[2-(2-aminopyridin-3-yl)-6-phenylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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|
C31H24N6O
|
3
|
| 1 |
IC50 = 160 nM
|
|
|
| 2 |
IC50 = 980 nM
|
|
|
| 3 |
IC50 = 1100 nM
|
|
|
|
CP0397469
|
N-[[4-[2-(2-aminopyridin-3-yl)-5-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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|
C30H23N7O
|
3
|
| 1 |
IC50 = 1400 nM
|
|
|
| 2 |
IC50 = 3200 nM
|
|
|
| 3 |
IC50 = 4200 nM
|
|
|
|
CP0024409
|
2-[4-[2-(2-aminopyridin-3-yl)imidazo[4,5-b]pyridin-3-yl]phenyl]-N-phenylacetamide
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|
C25H20N6O
|
2
|
| 1 |
IC50 = 2500 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0389516
|
N-[[4-[2-(2-aminopyridin-3-yl)-6-bromoimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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|
C25H19BrN6O
|
2
|
| 1 |
IC50 = 2500 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0397464
|
N-[[4-[2-(2-aminopyridin-3-yl)-6-cyclopentylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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|
C30H28N6O
|
3
|
| 1 |
IC50 = 3700 nM
|
|
|
| 2 |
IC50 = 9400 nM
|
|
|
| 3 |
IC50 > 10000 nM
|
|
|
|
CP0022681
|
N-[[4-[2-(2-aminopyridin-3-yl)imidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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|
C25H20N6O
|
2
|
| 1 |
IC50 = 5600 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0389475
|
N-[[4-[2-(2-aminopyridin-3-yl)-5-phenylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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|
C31H24N6O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
