Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[[4-[2-(2-aminopyridin-3-yl)-5-pyridin-3-ylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]-3-fluorobenzamide
    Show/Hide
 PubChem ID
CID: 58345302
SID: 144086963
Canonical SMILES
Nc1ncccc1-c1nc2ccc(nc2n1-c1ccc(CNC(=O)c2cccc(F)c2)cc1)-c1cccnc1
    Show/Hide
Compound Formula C30H22FN7O
Compound Structure
Protein Name
 Protein Info 
RAC-alpha serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31749
Gene Name
AKT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 190 nM
   TI
   LI
   LO
   TS
2
IC50 = 690 nM
   TI
   LI
   LO
   TS
3
IC50 = 1300 nM
   TI
   LI
   LO
   TS
CL000303 AN3-CA
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 95 nM
   TI
   LI
   LO
   TS
2
IC50 = 340 nM
   TI
   LI
   LO
   TS
3
IC50 = 2100 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 47 nM
   TI
   LI
   LO
   TS