Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[[4-[2-(2-aminopyridin-3-yl)-6-phenylimidazo[4,5-b]pyridin-3-yl]phenyl]methyl]benzamide
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 PubChem ID
CID: 58345169
SID: 144086766
Canonical SMILES
Nc1ncccc1-c1nc2cc(cnc2n1-c1ccc(CNC(=O)c2ccccc2)cc1)-c1ccccc1
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Compound Formula C31H24N6O
Compound Structure
Protein Name
 Protein Info 
RAC-alpha serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31749
Gene Name
AKT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000072 A2780
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 330 nM
   TI
   LI
   LO
   TS
2
IC50 = 680 nM
   TI
   LI
   LO
   TS
3
IC50 = 1800 nM
   TI
   LI
   LO
   TS
CL000303 AN3-CA
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 160 nM
   TI
   LI
   LO
   TS
2
IC50 = 980 nM
   TI
   LI
   LO
   TS
3
IC50 = 1100 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS