| Compound ID |
Compound Name |
Compound Formula |
|
CP0421428
|
US10562853, Compound 60
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|
C25H29ClF2N2O3
|
3
|
| 1 |
EC50 = 0.01023 nM
|
|
|
| 2 |
EC50 = 6.607 nM
|
|
|
| 3 |
EC50 = 53.7 nM
|
|
|
|
CP0432123
|
(3-chloro-4-fluorophenyl)-[4-[[2-(2,3-dihydro-1H-indol-4-yloxy)ethylamino]methyl]-4-fluoropiperidin-1-yl]methanone
Show/Hide
|
C23H26ClF2N3O2
|
3
|
| 1 |
EC50 = 0.01318 nM
|
|
|
| 2 |
EC50 = 3.548 nM
|
|
|
| 3 |
Ki = 0.04467 nM
|
|
|
|
CP0471529
|
US10562853, Compound 2
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|
C23H26ClF2N3O3
|
4
|
| 1 |
EC50 = 0.0138 nM
|
|
|
| 2 |
EC50 = 0.1778 nM
|
|
|
| 3 |
EC50 = 21.88 nM
|
|
|
| 4 |
Ki = 0.08318 nM
|
|
|
|
CP0479915
|
US10562853, Compound 44
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|
C23H24ClF2N3O2
|
3
|
| 1 |
EC50 = 0.02951 nM
|
|
|
| 2 |
EC50 = 0.0871 nM
|
|
|
| 3 |
EC50 = 14.45 nM
|
|
|
|
CP0421429
|
US10562853, Compound 3
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|
C23H26Cl2FN3O3
|
4
|
| 1 |
EC50 = 0.06607 nM
|
|
|
| 2 |
EC50 = 0.5888 nM
|
|
|
| 3 |
EC50 = 43.65 nM
|
|
|
| 4 |
Ki = 0.0537 nM
|
|
|
|
CP0479916
|
US10562853, Compound 52
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|
C22H26ClF2N3O2
|
4
|
| 1 |
EC50 = 0.07413 nM
|
|
|
| 2 |
EC50 = 0.1122 nM
|
|
|
| 3 |
EC50 = 32.36 nM
|
|
|
| 4 |
Ki = 0.03388 nM
|
|
|
|
CP0421434
|
US10562853, Compound 6
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|
C22H25ClF2N2O3
|
3
|
| 1 |
EC50 = 0.138 nM
|
|
|
| 2 |
EC50 = 0.302 nM
|
|
|
| 3 |
Ki = 0.0309 nM
|
|
|
|
CP0479920
|
US10562853, Compound 47
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|
C22H24ClF2N3O3
|
4
|
| 1 |
EC50 = 0.182 nM
|
|
|
| 2 |
EC50 = 0.6607 nM
|
|
|
| 3 |
EC50 = 38.02 nM
|
|
|
| 4 |
Ki = 0.02951 nM
|
|
|
|
CP0479922
|
US10562853, Compound 16
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|
C24H24ClF2N3O2
|
4
|
| 1 |
EC50 = 0.3388 nM
|
|
|
| 2 |
EC50 = 0.5012 nM
|
|
|
| 3 |
EC50 = 13.49 nM
|
|
|
| 4 |
Ki = 0.06026 nM
|
|
|
|
CP0479949
|
US10562853, Compound 8
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|
C22H25ClF2N2O3
|
4
|
| 1 |
EC50 = 0.3981 nM
|
|
|
| 2 |
EC50 = 1.047 nM
|
|
|
| 3 |
EC50 = 70.79 nM
|
|
|
| 4 |
Ki = 0.06026 nM
|
|
|
|
CP0032640
|
US10562853, Compound 18
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|
C20H22ClF2N3O2
|
3
|
| 1 |
EC50 = 0.4266 nM
|
|
|
| 2 |
EC50 = 8.913 nM
|
|
|
| 3 |
EC50 = 17.38 nM
|
|
|
|
CP0471680
|
US10562853, Compound 1
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|
C21H23ClF2N2O2
|
5
|
| 1 |
EC50 = 0.7943 nM
|
|
|
| 2 |
EC50 = 8.128 nM
|
|
|
| 3 |
EC50 = 40.74 nM
|
|
|
| 4 |
EC50 = 63.1 nM
|
|
|
| 5 |
Ki = 0.06166 nM
|
|
|
|
CP0424569
|
US10562853, Compound 74
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|
C20H22Cl2FN3O2
|
3
|
| 1 |
EC50 = 0.871 nM
|
|
|
| 2 |
EC50 = 9.12 nM
|
|
|
| 3 |
EC50 = 38.9 nM
|
|
|
|
CP0479952
|
US10562853, Compound 51
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|
C22H26ClF2N3O2
|
4
|
| 1 |
EC50 = 1.38 nM
|
|
|
| 2 |
EC50 = 15.14 nM
|
|
|
| 3 |
EC50 = 102.33 nM
|
|
|
| 4 |
Ki = 0.1175 nM
|
|
|
|
CP0421427
|
US10562853, Compound 63
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|
C22H25ClF2N2O2
|
4
|
| 1 |
EC50 = 1.905 nM
|
|
|
| 2 |
EC50 = 14.79 nM
|
|
|
| 3 |
EC50 = 147.91 nM
|
|
|
| 4 |
Ki = 0.1413 nM
|
|
|
|
CP0484979
|
US10562853, Compound 48
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|
C22H24ClF2N3O3
|
4
|
| 1 |
EC50 = 2.089 nM
|
|
|
| 2 |
EC50 = 6.026 nM
|
|
|
| 3 |
EC50 = 29.51 nM
|
|
|
| 4 |
Ki = 0.06026 nM
|
|
|
|
CP0531461
|
Adatanserin hydrochloride
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|
C21H32ClN5O
|
1
|
| 1 |
EC50 = 2.1 nM
|
|
|
|
CP0479951
|
US10562853, Compound 5
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|
C21H22ClF3N2O2
|
4
|
| 1 |
EC50 = 2.291 nM
|
|
|
| 2 |
EC50 = 15.85 nM
|
|
|
| 3 |
EC50 = 69.18 nM
|
|
|
| 4 |
Ki = 0.0166 nM
|
|
|
|
CP0378668
|
(3-chloro-4-fluorophenyl)-[4-fluoro-4-[[(5-methylpyrimidin-2-yl)methylamino]methyl]piperidin-1-yl]methanone
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|
C19H21ClF2N4O
|
5
|
| 1 |
EC50 = 4.677 nM
|
|
|
| 2 |
EC50 = 60.26 nM
|
|
|
| 3 |
EC50 = 245.47 nM
|
|
|
| 4 |
EC50 = 302 nM
|
|
|
| 5 |
Ki = 2.188 nM
|
|
|
|
CP0421401
|
US10562853, Compound 36
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|
C19H21ClF2N4O2
|
3
|
| 1 |
EC50 = 4.898 nM
|
|
|
| 2 |
EC50 = 20.89 nM
|
|
|
| 3 |
EC50 = 28.84 nM
|
|
|
|
CP0001238
|
14C-5-hydroxy tryptamine creatinine disulfate
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|
C10H12N2O
|
20
|
| 1 |
EC50 = 5.7 nM
|
|
|
| 2 |
EC50 = 15.33 nM
|
|
|
| 3 |
EC50 = 18 nM
|
|
|
| 4 |
EC50 = 30.9 nM
|
|
|
| 5 |
EC50 = 33.11 nM
|
|
|
| 6 |
EC50 = 39 nM
|
|
|
| 7 |
EC50 = 45.3 nM
|
|
|
| 8 |
EC50 = 50.12 nM
|
|
|
| 9 |
EC50 = 58.88 nM
|
|
|
| 10 |
EC50 = 69.18 nM
|
|
|
| 11 |
EC50 = 97.7 nM
|
|
|
| 12 |
EC50 = 1800 nM
|
|
|
| 13 |
Ki = 0.91 nM
|
|
|
| 14 |
Ki = 1.1 nM
|
|
|
| 15 |
Ki = 1.3 nM
|
|
|
| 16 |
Ki = 1.4 nM
|
|
|
| 17 |
Ki = 2.08 nM
|
|
|
| 18 |
Ki = 2.48 nM
|
|
|
| 19 |
Ki = 3.6 nM
|
|
|
| 20 |
Ki = 5.5 nM
|
|
|
|
CP0421456
|
US10562853, Compound 64
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|
C21H22ClF3N2O2
|
4
|
| 1 |
EC50 = 5.754 nM
|
|
|
| 2 |
EC50 = 42.66 nM
|
|
|
| 3 |
EC50 = 100 nM
|
|
|
| 4 |
Ki = 0.07943 nM
|
|
|
|
CP0479918
|
US10562853, Compound 61
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|
C21H22ClF3N2O2
|
4
|
| 1 |
EC50 = 5.754 nM
|
|
|
| 2 |
EC50 = 18.2 nM
|
|
|
| 3 |
EC50 = 151.36 nM
|
|
|
| 4 |
Ki = 0.01585 nM
|
|
|
|
CP0471528
|
US10562853, Compound 45
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|
C23H28ClF2N3O2
|
4
|
| 1 |
EC50 = 6.026 nM
|
|
|
| 2 |
EC50 = 16.98 nM
|
|
|
| 3 |
EC50 = 138.04 nM
|
|
|
| 4 |
Ki = 0.302 nM
|
|
|
|
CP0420311
|
N-[2-(4-pyrimidin-2-ylpiperazin-1-yl)ethyl]adamantane-1-carbothioamide
Show/Hide
|
C21H31N5S
|
1
|
| 1 |
EC50 = 6.7 nM
|
|
|
|
CP0424643
|
US10562853, Compound 9
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|
C22H25Cl2FN2O3
|
4
|
| 1 |
EC50 = 7.244 nM
|
|
|
| 2 |
EC50 = 20.42 nM
|
|
|
| 3 |
EC50 = 316.23 nM
|
|
|
| 4 |
Ki = 0.03162 nM
|
|
|
|
CP0037227
|
7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol
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|
C16H25NO
|
5
|
| 1 |
EC50 = 8.128 nM
|
|
|
| 2 |
EC50 = 21.88 nM
|
|
|
| 3 |
EC50 = 31.62 nM
|
|
|
| 4 |
Ki = 0.8128 nM
|
|
|
| 5 |
Ki = 2.65 nM
|
|
|
|
CP0479950
|
US10562853, Compound 4
Show/Hide
|
C21H22Cl2F2N2O2
|
4
|
| 1 |
EC50 = 10.23 nM
|
|
|
| 2 |
EC50 = 19.5 nM
|
|
|
| 3 |
EC50 = 251.19 nM
|
|
|
| 4 |
Ki = 0.04786 nM
|
|
|
|
CP0415732
|
4-[(2R)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
EC50 = 11 nM
|
|
|
|
CP0466157
|
US10562853, Compound 55
Show/Hide
|
C21H24ClF2N3O
|
3
|
| 1 |
EC50 = 12.59 nM
|
|
|
| 2 |
EC50 = 14.45 nM
|
|
|
| 3 |
EC50 = 46.77 nM
|
|
|
|
CP0424570
|
US10562853, Compound 40
Show/Hide
|
C20H22ClF2N3OS
|
3
|
| 1 |
EC50 = 12.88 nM
|
|
|
| 2 |
EC50 = 66.07 nM
|
|
|
| 3 |
EC50 = 112.2 nM
|
|
|
|
CP0421399
|
US10562853, Compound 59
Show/Hide
|
C22H25ClF2N2O
|
3
|
| 1 |
EC50 = 13.18 nM
|
|
|
| 2 |
EC50 = 79.43 nM
|
|
|
| 3 |
EC50 = 85.11 nM
|
|
|
|
CP0042717
|
(buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-8-aza-spiro[4.5]decane-7,9-dione
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|
C21H31N5O2
|
5
|
| 1 |
EC50 = 15.14 nM
|
|
|
| 2 |
EC50 = 38.02 nM
|
|
|
| 3 |
EC50 = 72.44 nM
|
|
|
| 4 |
Ki = 5.012 nM
|
|
|
| 5 |
Ki = 21 nM
|
|
|
|
CP0421400
|
US10562853, Compound 54
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|
C20H23ClF2N4O
|
3
|
| 1 |
EC50 = 17.38 nM
|
|
|
| 2 |
EC50 = 54.95 nM
|
|
|
| 3 |
EC50 = 74.13 nM
|
|
|
|
CP0421480
|
(3,4-dichlorophenyl)-[4-fluoro-4-[[2-(3-fluorophenoxy)ethylamino]methyl]piperidin-1-yl]methanone
Show/Hide
|
C21H22Cl2F2N2O2
|
4
|
| 1 |
EC50 = 19.95 nM
|
|
|
| 2 |
EC50 = 39.81 nM
|
|
|
| 3 |
EC50 = 645.65 nM
|
|
|
| 4 |
Ki = 0.02042 nM
|
|
|
|
CP0448031
|
US10562853, Compound 10
Show/Hide
|
C22H25ClF2N2O3
|
4
|
| 1 |
EC50 = 20.89 nM
|
|
|
| 2 |
EC50 = 562.34 nM
|
|
|
| 3 |
EC50 = 616.6 nM
|
|
|
| 4 |
Ki = 6.607 nM
|
|
|
|
CP0507465
|
US10562853, Compound 19
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|
C20H22ClF2N3O2
|
3
|
| 1 |
EC50 = 23.99 nM
|
|
|
| 2 |
EC50 = 45.71 nM
|
|
|
| 3 |
EC50 = 47.86 nM
|
|
|
|
CP0432139
|
US10562853, Compound 62
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|
C21H22Cl2F2N2O2
|
3
|
| 1 |
EC50 = 25.7 nM
|
|
|
| 2 |
EC50 = 549.54 nM
|
|
|
| 3 |
Ki = 0.01288 nM
|
|
|
|
CP0424571
|
US10562853, Compound 53
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|
C21H24ClF2N3O
|
3
|
| 1 |
EC50 = 25.7 nM
|
|
|
| 2 |
EC50 = 104.71 nM
|
|
|
| 3 |
EC50 = 186.21 nM
|
|
|
|
CP0086335
|
4-[(2S)-2-[2-[4-(1-benzothiophen-4-yl)piperazin-1-yl]ethyl]pyrrolidin-1-yl]sulfonylisoquinoline
Show/Hide
|
C27H30N4O2S2
|
1
|
| 1 |
EC50 = 28.3 nM
|
|
|
|
CP0479919
|
US10562853, Compound 11
Show/Hide
|
C22H25Cl2FN2O3
|
4
|
| 1 |
EC50 = 47.86 nM
|
|
|
| 2 |
EC50 = 331.13 nM
|
|
|
| 3 |
EC50 = 1318.26 nM
|
|
|
| 4 |
Ki = 1.23 nM
|
|
|
|
CP0555328
|
US10562853, Compound 35
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|
C20H23ClF2N4O2
|
2
|
| 1 |
EC50 = 52.48 nM
|
|
|
| 2 |
EC50 = 933.25 nM
|
|
|
|
CP0471679
|
US10562853, Compound 46
Show/Hide
|
C22H22ClF5N2O2
|
4
|
| 1 |
EC50 = 56.23 nM
|
|
|
| 2 |
EC50 = 275.42 nM
|
|
|
| 3 |
EC50 = 724.44 nM
|
|
|
| 4 |
Ki = 0.2754 nM
|
|
|
|
CP0563365
|
methyl (2S)-2-[(2S,3R,12bR)-3-ethenyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-hydroxypropanoate
Show/Hide
|
C21H26N2O3
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0479927
|
US10562853, Compound 65
Show/Hide
|
C21H22Cl2F2N2O2
|
4
|
| 1 |
EC50 = 117.49 nM
|
|
|
| 2 |
EC50 = 478.63 nM
|
|
|
| 3 |
EC50 = 5248.07 nM
|
|
|
| 4 |
Ki = 3.89 nM
|
|
|
|
CP0546077
|
(3-chloro-4-fluorophenyl)-[4-fluoro-4-[(2-phenylsulfanylethylamino)methyl]piperidin-1-yl]methanone
Show/Hide
|
C21H23ClF2N2OS
|
2
|
| 1 |
EC50 = 169.82 nM
|
|
|
| 2 |
EC50 = 2454.71 nM
|
|
|
|
CP0412119
|
5-fluoro-3-[3-[4-(4-fluoro-2-phenylphenyl)piperidin-1-yl]propyl]-1H-indole
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|
C28H28F2N2
|
1
|
| 1 |
EC50 = 1180 nM
|
|
|
|
CP0402219
|
methyl (1S,15R,16S,17S,21S)-15-hydroxy-17-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-18-oxa-3,13-diazapentacyclo[11.9.0.02,10.04,9.016,21]docosa-2(10),4,6,8,19-pentaene-20-carboxylate
Show/Hide
|
C27H34N2O10
|
1
|
| 1 |
EC50 = 1600 nM
|
|
|
|
CP0525583
|
CHEBI:70071
Show/Hide
|
C22H28N2O4
|
1
|
| 1 |
EC50 = 2000 nM
|
|
|
|
CP0402217
|
methyl (2S)-2-[(2S,3R,12bR)-3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-hydroxypropanoate
Show/Hide
|
C21H28N2O3
|
1
|
| 1 |
EC50 = 2200 nM
|
|
|
|
CP0409289
|
benzyl N-[2-(1-benzyl-4-pyrimidin-2-ylpiperazin-1-ium-1-yl)ethyl]adamantane-1-carboximidothioate;bromide
Show/Hide
|
C35H44BrN5S
|
1
|
| 1 |
EC50 = 4966 nM
|
|
|
|
CP0432152
|
N-[4-[2-[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]ethyl]cyclohexyl]furan-2-carboxamide
Show/Hide
|
C24H30N4O2S
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 46.12 nM
|
|
|
|
CP0548643
|
methyl N-[2-(1-methyl-4-pyrimidin-2-ylpiperazin-1-ium-1-yl)ethyl]adamantane-1-carboximidothioate;iodide
Show/Hide
|
C23H36IN5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0554553
|
methyl (E)-2-[(3R,7'R,8'S,9'aR)-7'-ethenyl-2-oxospiro[1H-indole-3,2'-4,6,7,8,9,9a-hexahydro-3H-pyrido[2,1-b][1,3]oxazine]-8'-yl]-3-methoxyprop-2-enoate
Show/Hide
|
C22H26N2O5
|
1
|
| 1 |
EC50 = 10100 nM
|
|
|
|
CP0525582
|
methyl (1S,15R,16S,17S,21S)-17-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-18,23-dioxa-3,13-diazahexacyclo[13.7.1.01,13.02,10.04,9.016,21]tricosa-2(10),4,6,8,19-pentaene-20-carboxylate
Show/Hide
|
C27H32N2O10
|
1
|
| 1 |
EC50 = 10200 nM
|
|
|
|
CP0357291
|
methyl (E)-2-[(3R,6'R,7'S,8'aS)-6'-ethyl-2-oxospiro[1H-indole-3,1'-3,5,6,7,8,8a-hexahydro-2H-indolizine]-7'-yl]-3-methoxyprop-2-enoate
Show/Hide
|
C22H28N2O4
|
1
|
| 1 |
EC50 = 10300 nM
|
|
|
|
CP0565211
|
methyl (2R)-2-[(2R,3Z,5S,12bS)-3-ethylidene-5-oxido-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-5-ium-2-yl]-3-hydroxypropanoate
Show/Hide
|
C21H26N2O4
|
1
|
| 1 |
EC50 = 11400 nM
|
|
|
|
CP0565210
|
methyl (2R)-2-[(2S,3R,12bR)-3-ethenyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-hydroxypropanoate
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C21H26N2O3
|
1
|
| 1 |
EC50 = 54400 nM
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CP0402218
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methyl (E)-2-[(2S,3R,5S,12bR)-3-ethenyl-5-oxido-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-5-ium-2-yl]-3-methoxyprop-2-enoate
Show/Hide
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C22H26N2O4
|
1
|
| 1 |
EC50 = 85000 nM
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CP0077622
|
TETRAHYDROALSTONINE
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C21H24N2O3
|
1
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| 1 |
EC50 > 100000 nM
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CP0402220
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methyl (E)-2-[(2S,3R,12bS)-3-ethenyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate
Show/Hide
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C22H26N2O3
|
1
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| 1 |
EC50 > 100000 nM
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CP0402221
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methyl (E)-2-[(2S,3E,12bS)-3-ethylidene-5-oxido-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-5-ium-2-yl]-3-methoxyprop-2-enoate
Show/Hide
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C22H26N2O4
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1
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| 1 |
EC50 > 100000 nM
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CP0402222
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(1R,18S,19R,20S)-19-ethenyl-18-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,15-pentaen-14-one
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C26H30N2O8
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1
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| 1 |
EC50 > 100000 nM
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CP0440282
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methyl (E)-2-[(2R,3R,5R,12bR)-3-ethyl-5-oxido-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-5-ium-2-yl]-3-methoxyprop-2-enoate
Show/Hide
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C22H28N2O4
|
1
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| 1 |
EC50 > 100000 nM
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CP0459756
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methyl (E)-2-[(2R,3R,12bR)-3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate
Show/Hide
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C22H28N2O3
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1
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| 1 |
EC50 > 100000 nM
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CP0474174
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methyl (E)-2-[(2S,3Z,12bR)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate
Show/Hide
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C22H26N2O3
|
1
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| 1 |
EC50 > 100000 nM
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CP0524573
|
Isocorynoxeine
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C22H26N2O4
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1
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| 1 |
EC50 > 100000 nM
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CP0553720
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methyl (E)-2-[(2S,3R,12bR)-3-ethyl-5-oxido-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-5-ium-2-yl]-3-methoxyprop-2-enoate
Show/Hide
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C22H28N2O4
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1
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| 1 |
EC50 > 100000 nM
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CP0567464
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methyl (E)-2-[(2S,3R,7aR,12bR)-3-ethenyl-7a-hydroxy-2,3,4,6,7,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate
Show/Hide
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C22H26N2O4
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1
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| 1 |
EC50 > 100000 nM
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CP0567465
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methyl (2R)-2-[(2S,3R,12bR)-3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-hydroxypropanoate
Show/Hide
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C21H28N2O3
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1
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| 1 |
EC50 > 100000 nM
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CP0571571
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(1S,18S,19R,20S)-19-ethenyl-18-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,15-pentaen-14-one
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C26H30N2O8
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1
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| 1 |
EC50 > 100000 nM
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CP0036542
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(phenylmethyl) N-[[(6aR,9S,10aR)-4,7-dimethyl-6,6a,8,9,10,10a-hexahydroindolo[4,3-fg]quinoline-9-yl]methyl]carbamate
Show/Hide
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C25H29N3O2
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2
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| 1 |
IC50 = 4.1 nM
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| 2 |
Ki = 2.3 nM
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CP0259093
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N-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
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C24H29N3O3S
|
1
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| 1 |
IC50 = 4.6 nM
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CP0042265
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2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-isoindole-1,3-dione
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C23H27N3O3
|
3
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| 1 |
IC50 = 4.73 nM
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| 2 |
IC50 = 5 nM
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| 3 |
Ki = 87 nM
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CP0780574
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N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-cyclohexanecarboxamide tri hydrochloride
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C25H35ClN4O2
|
1
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| 1 |
IC50 = 4.9 nM
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CP0867161
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1-[3-(2,4-Dimethylphenoxy)propyl]-4-(2-methoxyphenyl)piperazine hydrochloride
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C22H31ClN2O2
|
1
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| 1 |
IC50 = 7.19 nM
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CP0451834
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4-[(2-bromo-5-methoxyphenyl)methyl]-1-[1-(3,4-dimethoxyphenyl)piperidin-4-yl]piperidine
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C26H35BrN2O3
|
1
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| 1 |
IC50 < 10 nM
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CP0224658
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8-chloro-7-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butoxy]-4-methylchromen-2-one
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C26H26ClFN2O4
|
1
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| 1 |
IC50 = 11.8 nM
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CP0037692
|
CAS_133025-23-7
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C24H33N3O2
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1
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| 1 |
IC50 = 16.9 nM
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CP0386709
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8-acetyl-7-[4-[4-(3-methoxyphenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
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C27H32N2O5
|
2
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| 1 |
IC50 = 23 nM
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| 2 |
Ki = 0.8 nM
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CP0489015
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8-acetyl-7-[4-[4-(2-fluorophenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
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C26H29FN2O4
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2
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| 1 |
IC50 = 28 nM
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| 2 |
Ki = 1 nM
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CP0419082
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N-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
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C24H26F3N3O2S
|
1
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| 1 |
IC50 = 29 nM
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CP0699181
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N-{2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl}-N-(2-pyridinyl)cyclohexane carboxamide trihydrochloride
Show/Hide
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C25H37Cl3N4O2
|
1
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| 1 |
IC50 = 37 nM
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CP0386712
|
2-[4-[4-(8-acetyl-4-methyl-2-oxochromen-7-yl)oxybutyl]piperazin-1-yl]benzonitrile
Show/Hide
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C27H29N3O4
|
2
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| 1 |
IC50 = 38 nM
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| 2 |
Ki = 1.5 nM
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CP0459682
|
4-Methoxy-N-{3-[4-(m-trifluoromethylphenyl)-piperazin-1-yl]-1-methyl-propyl}-benzenesulfonamide
Show/Hide
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C22H28F3N3O3S
|
1
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| 1 |
IC50 = 39 nM
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CP0501817
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4-Methoxy-N-{3-[4-(p-fluorophenyl)-piperazin-1-yl]-propyl}-benzenesulfonamide
Show/Hide
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C20H26FN3O3S
|
1
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| 1 |
IC50 = 39 nM
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CP0419080
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4-Methoxy-N-{3-[4-(m-trifluoromethylphenyl)-piperazin-1-yl]-propyl}-benzenesulfonamide
Show/Hide
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C21H26F3N3O3S
|
1
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| 1 |
IC50 = 44 nM
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CP0386707
|
8-acetyl-7-[3-[4-(3-methoxyphenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
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C26H30N2O5
|
2
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| 1 |
IC50 = 48 nM
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| 2 |
Ki = 1.6 nM
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CP0864251
|
1-{2-[2-(Mesityloxy)ethoxy]ethyl}-4-(2-methoxyphenyl)piperazine dihydrochloride
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C24H36Cl2N2O3
|
1
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| 1 |
IC50 = 56.8 nM
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CP0377208
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N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
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C21H23N3O2S
|
1
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| 1 |
IC50 = 57 nM
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CP0695796
|
SID50106634
Show/Hide
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C21H28N2O3S3
|
1
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| 1 |
IC50 = 71 nM
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CP0377202
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N-methyl-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
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C22H25N3O2S
|
1
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| 1 |
IC50 = 95 nM
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CP0386708
|
2-[4-[3-(8-acetyl-4-methyl-2-oxochromen-7-yl)oxypropyl]piperazin-1-yl]benzonitrile
Show/Hide
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C26H27N3O4
|
2
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| 1 |
IC50 = 99 nM
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| 2 |
Ki = 1 nM
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CP0386710
|
8-acetyl-7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
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C26H28Cl2N2O4
|
2
|
| 1 |
IC50 = 180 nM
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| 2 |
Ki = 2.2 nM
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CP0387316
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8-acetyl-7-[3-[4-(2-fluorophenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
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C25H27FN2O4
|
2
|
| 1 |
IC50 = 190 nM
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| 2 |
Ki = 1.3 nM
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CP0373060
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N-[3-[4-(3,4-dichlorophenyl)piperazin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
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C23H25Cl2N3O2S
|
1
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| 1 |
IC50 = 215 nM
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CP0233824
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4-Methoxy-N-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-propyl}-benzenesulfonamide
Show/Hide
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C21H29N3O4S
|
1
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| 1 |
IC50 = 272 nM
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CP0417851
|
N-benzyl-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
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C28H29N3O2S
|
1
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| 1 |
IC50 = 280 nM
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CP0873148
|
1-[3-(4-Chloro-3-methylphenoxy)propyl]-4-phenylpiperazine dihydrochloride
Show/Hide
|
C20H27Cl3N2O
|
1
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| 1 |
IC50 = 291 nM
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CP0398637
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylnaphthalene-1-sulfonamide
Show/Hide
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C24H29N3O2S
|
1
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| 1 |
IC50 = 298 nM
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CP0873149
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1-(2-Methoxyphenyl)-4-{2-[2-(2,3,5-trimethylphenoxy)ethoxy]ethyl}piperazine dihydrochloride
Show/Hide
|
C24H36Cl2N2O3
|
1
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| 1 |
IC50 = 376 nM
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CP0416325
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N-ethyl-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
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C23H27N3O2S
|
1
|
| 1 |
IC50 = 485 nM
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CP0853338
|
1-[3-(Mesityloxy)propyl]-4-(4-methoxyphenyl)piperazine dihydrochloride
Show/Hide
|
C23H34Cl2N2O2
|
1
|
| 1 |
IC50 = 595 nM
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CP0416326
|
N-(cyclopropylmethyl)-N-[3-(4-methylpiperazin-1-yl)phenyl]naphthalene-2-sulfonamide
Show/Hide
|
C25H29N3O2S
|
1
|
| 1 |
IC50 = 672 nM
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CP0902025
|
1-{2-[2-(Mesityloxy)ethoxy]ethyl}-4-phenethylpiperazine dihydrochloride
Show/Hide
|
C25H38Cl2N2O2
|
1
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| 1 |
IC50 = 1180 nM
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CP0366351
|
1-(dimethylamino)-3-[(2-methyl-1H-1,2-benzazaborinin-5-yl)oxy]propan-2-ol
Show/Hide
|
C14H21BN2O2
|
1
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| 1 |
IC50 = 1995.26 nM
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CP0417858
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylbenzenesulfonamide
Show/Hide
|
C20H27N3O2S
|
1
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| 1 |
IC50 = 3399 nM
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CP0487098
|
N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propylnaphthalene-2-sulfonamide
Show/Hide
|
C24H29N3O2S
|
1
|
| 1 |
IC50 = 3756 nM
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CP0041613
|
Anapriline
Show/Hide
|
C16H21NO2
|
1
|
| 1 |
IC50 = 3981.07 nM
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CP0398640
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N-[3-(4-methylpiperazin-1-yl)phenyl]-N-propan-2-ylnaphthalene-2-sulfonamide
Show/Hide
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C24H29N3O2S
|
1
|
| 1 |
IC50 > 1000 nM
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CP0066236
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1-(dimethylamino)-3-[(2-methyl-1H-1,2-benzazaborinin-8-yl)oxy]propan-2-ol
Show/Hide
|
C14H21BN2O2
|
1
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| 1 |
IC50 > 5011.87 nM
|
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CP0552411
|
[4-[[2-(3-chlorophenoxy)ethylamino]methyl]-4-fluoropiperidin-1-yl]-(3,4-dichlorophenyl)methanone
Show/Hide
|
C21H22Cl3FN2O2
|
1
|
| 1 |
Ki = 0.02512 nM
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CP0241906
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7-(4-(4-(1-benzothiophen-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-one
Show/Hide
|
C25H27N3O2S
|
1
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| 1 |
Ki = 0.12 nM
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CP0552412
|
US10562853, Compound 14
Show/Hide
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C23H25ClF2N2O4
|
1
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| 1 |
Ki = 0.138 nM
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CP0386401
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3-[7-[4-(2-methoxyphenyl)piperazin-1-yl]heptyl]-1,3-benzoxazol-2-one
Show/Hide
|
C25H33N3O3
|
1
|
| 1 |
Ki = 0.19 nM
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CP0479917
|
US10562853, Compound 15
Show/Hide
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C23H25Cl2FN2O4
|
1
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| 1 |
Ki = 0.195 nM
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CP0555203
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3-[7-[4-(2-methoxyphenyl)piperazin-1-yl]heptyl]-1,3-benzothiazol-2-one
Show/Hide
|
C25H33N3O2S
|
1
|
| 1 |
Ki = 0.21 nM
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CP0001212
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1-(2-methoxyphenyl)-4-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]piperazine
Show/Hide
|
C23H29N5OS
|
1
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| 1 |
Ki = 0.22 nM
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CP0418286
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3-[7-(4-phenylpiperazin-1-yl)heptyl]-1,3-benzothiazol-2-one
Show/Hide
|
C24H31N3OS
|
1
|
| 1 |
Ki = 0.27 nM
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CP0852532
|
6-acetyl-4,7-dimethyl-5-{3-[4-(2-fluorophenyl)piperazin-1-yl]propoxy}coumarin
Show/Hide
|
C26H29FN2O4
|
1
|
| 1 |
Ki = 0.3 nM
|
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CP0857130
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6-acetyl-4,7-dimethyl-5-{3-[4-(2-cyanophenyl)piperazin-1-yl]-propoxy}coumarin
Show/Hide
|
C27H29N3O4
|
1
|
| 1 |
Ki = 0.3 nM
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CP0437880
|
N-benzyl-3-(4-benzylpiperazin-1-yl)propanamide
Show/Hide
|
C21H27N3O
|
1
|
| 1 |
Ki = 0.34 nM
|
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CP0376985
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-[2-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]piperidine
Show/Hide
|
C23H28BrNO3
|
1
|
| 1 |
Ki = 0.36 nM
|
|
|
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CP0484978
|
US10562853, Compound 7
Show/Hide
|
C22H25Cl2FN2O3
|
1
|
| 1 |
Ki = 0.3802 nM
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CP0864708
|
6-acetyl-4,7-dimethyl-5-{3-[4-(3-methoxyphenyl)-piperazin-1-yl]propoxy}coumarin
Show/Hide
|
C27H32N2O5
|
1
|
| 1 |
Ki = 0.4 nM
|
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CP0891134
|
6-acetyl-4,7-dimethyl-5-{3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propoxy}coumarin
Show/Hide
|
C26H28Cl2N2O4
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
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CP0564999
|
US10562853, Compound 17
Show/Hide
|
C24H24Cl2FN3O2
|
1
|
| 1 |
Ki = 0.4266 nM
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CP0383726
|
3-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexyl]-1,3-benzothiazol-2-one
Show/Hide
|
C24H31N3O2S
|
1
|
| 1 |
Ki = 0.43 nM
|
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|
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CP0410273
|
1-[3-[2-(4-phenylpiperazin-1-yl)ethyl]phenyl]-3-pyridin-4-ylurea
Show/Hide
|
C24H27N5O
|
1
|
| 1 |
Ki = 0.5 nM
|
|
|
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CP0416077
|
8-acetyl-7-[3-[4-(2-bromophenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C25H27BrN2O4
|
1
|
| 1 |
Ki = 0.5 nM
|
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|
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CP0420913
|
2-phenyl-N-[3-[2-(4-phenylpiperazin-1-yl)ethyl]phenyl]acetamide
Show/Hide
|
C26H29N3O
|
1
|
| 1 |
Ki = 0.58 nM
|
|
|
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CP0541206
|
8-acetyl-7-[3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C26H30N2O5
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
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CP0869883
|
6-acetyl-4,7-dimethyl-5-{4-[4-(2-fluorophenyl)piperazin-1-yl]butoxy}coumarin
Show/Hide
|
C27H31FN2O4
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
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CP0420644
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-[2-(4-methoxyphenyl)ethyl]piperidine
Show/Hide
|
C22H28BrNO2
|
1
|
| 1 |
Ki = 0.81 nM
|
|
|
|
CP0376987
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-[2-(3-methoxyphenyl)ethyl]piperidine
Show/Hide
|
C22H28BrNO2
|
1
|
| 1 |
Ki = 0.82 nM
|
|
|
|
CP0376984
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-(2-naphthalen-2-ylethyl)piperidine
Show/Hide
|
C25H28BrNO
|
1
|
| 1 |
Ki = 0.89 nM
|
|
|
|
CP0466084
|
8-acetyl-7-[3-[4-(3,5-dimethylphenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C27H32N2O4
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0490833
|
8-acetyl-7-[4-[4-(2-chlorophenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C26H29ClN2O4
|
1
|
| 1 |
Ki = 0.9 nM
|
|
|
|
CP0379154
|
3-[6-(4-phenylpiperazin-1-yl)hexyl]-1,3-benzothiazol-2-one
Show/Hide
|
C23H29N3OS
|
1
|
| 1 |
Ki = 0.91 nM
|
|
|
|
CP0160735
|
OXITRIPTAN
Show/Hide
|
C11H12N2O3
|
1
|
| 1 |
Ki = 0.91 nM
|
|
|
|
CP0548887
|
1-[3-[2-(4-phenylpiperazin-1-yl)ethyl]phenyl]-3-pyridin-3-ylurea
Show/Hide
|
C24H27N5O
|
1
|
| 1 |
Ki = 0.95 nM
|
|
|
|
CP0446193
|
2-(5-{3-[3-(2-Amino-ethyl)-1H-indol-5-yloxymethyl]-benzyloxy}-1H-indol-3-yl)-ethylamine
Show/Hide
|
C28H30N4O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0408141
|
N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3-fluorobenzenesulfonamide
Show/Hide
|
C21H21ClFN3O2S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0429556
|
N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-4-fluorobenzenesulfonamide
Show/Hide
|
C21H21ClFN3O2S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0457174
|
8-acetyl-7-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C27H32N2O5
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0903003
|
4,7-dimethyl-5-{4-[4-(3-methoxyphenyl)piperazin-1-yl]butoxy}coumarin
Show/Hide
|
C26H32N2O4
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0429435
|
3-[5-[4-(2-ethoxyphenyl)piperazin-1-yl]pentyl]-5,6-dimethylthieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C25H34N4O2S
|
1
|
| 1 |
Ki = 1.03 nM
|
|
|
|
CP0451848
|
3-[5-[4-(2-ethoxyphenyl)piperazin-1-yl]pentyl]quinazolin-4-one
Show/Hide
|
C25H32N4O2
|
1
|
| 1 |
Ki = 1.04 nM
|
|
|
|
CP0376983
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-[2-(3-chloro-4-methoxyphenyl)ethyl]piperidine
Show/Hide
|
C22H27BrClNO2
|
1
|
| 1 |
Ki = 1.04 nM
|
|
|
|
CP0408309
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-[2-(4-fluorophenyl)ethyl]piperidine
Show/Hide
|
C21H25BrFNO
|
1
|
| 1 |
Ki = 1.04 nM
|
|
|
|
CP0408310
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-[2-(2-chloro-4-methoxyphenyl)ethyl]piperidine
Show/Hide
|
C22H27BrClNO2
|
1
|
| 1 |
Ki = 1.12 nM
|
|
|
|
CP0905189
|
6-acetyl-4,7-dimethyl-5-{3-[4-(4-chlorophenyl)piperazin-1-yl]propoxy}coumarin
Show/Hide
|
C26H29ClN2O4
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0190867
|
(E)-3-[3-(2-Dimethylamino-ethyl)-1H-indol-5-yl]-N-(4-methoxy-benzyl)-acrylamide
Show/Hide
|
C23H27N3O2
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0418281
|
3-[6-[4-(2-methoxyphenyl)piperazin-1-yl]hexyl]-1,3-benzoxazol-2-one
Show/Hide
|
C24H31N3O3
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0466993
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-[2-(4-chlorophenyl)ethyl]piperidine
Show/Hide
|
C21H25BrClNO
|
1
|
| 1 |
Ki = 1.34 nM
|
|
|
|
CP0443954
|
N-[3-[2-(4-phenylpiperazin-1-yl)ethyl]phenyl]-2-pyridin-3-ylacetamide
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
Ki = 1.39 nM
|
|
|
|
CP0446566
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-[2-(4-methylphenyl)ethyl]piperidine
Show/Hide
|
C22H28BrNO
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0519825
|
8-acetyl-7-[4-[4-(2-bromophenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C26H29BrN2O4
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0869884
|
2-(4-(4-(4,7-dimethyl-2-oxo-2H-chromen-5-yloxy)butyl)piperazin-1-yl)benzonitrile
Show/Hide
|
C26H29N3O3
|
1
|
| 1 |
Ki = 1.5 nM
|
|
|
|
CP0451831
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-[2-(3,4-dimethoxyphenyl)ethyl]piperidine
Show/Hide
|
C23H30BrNO3
|
1
|
| 1 |
Ki = 1.56 nM
|
|
|
|
CP0234879
|
2-(5-((4-((3-(2-aminoethyl)-1H-indol-5-yloxy)methyl)phenyl)methoxy)-1H-indol-3-yl)ethanamine
Show/Hide
|
C28H30N4O2
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0520931
|
8-acetyl-7-[3-[4-(2,3-dichlorophenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C25H26Cl2N2O4
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0372361
|
Biphenyl-4,4'-disulfonic acid bis-({6-[3-(2-amino-ethyl)-1H-indol-5-yloxy]-hexyl}-amide)
Show/Hide
|
C44H56N6O6S2
|
1
|
| 1 |
Ki = 1.66 nM
|
|
|
|
CP0472939
|
3-chloro-N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]benzenesulfonamide
Show/Hide
|
C23H25Cl2N3O2S
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0852531
|
5-(4-(4-(2-fluorophenyl)piperazin-1-yl)butoxy)-4,7-dimethyl-2H-chromen-2-one
Show/Hide
|
C25H29FN2O3
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0042927
|
7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-3,4-dihydroquinolin-2(1H)-one
Show/Hide
|
C23H27Cl2N3O2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0460901
|
2-(5-{6-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-hexyloxy}-1H-indol-3-yl)-ethylamine
Show/Hide
|
C26H34N4O2
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0393445
|
N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3-methylbenzenesulfonamide
Show/Hide
|
C22H24ClN3O2S
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0408311
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-[2-(2-chloro-4,5-dimethoxyphenyl)ethyl]piperidine
Show/Hide
|
C23H29BrClNO3
|
1
|
| 1 |
Ki = 1.96 nM
|
|
|
|
CP0490834
|
8-acetyl-7-[3-[4-(2-chlorophenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C25H27ClN2O4
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0422046
|
2-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]-3H-thieno[3,2-d]pyrimidin-4-one
Show/Hide
|
C20H23ClN4OS
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0452064
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-[2-(2,3-dihydro-1,4-benzodioxin-5-yl)ethyl]piperidine
Show/Hide
|
C23H28BrNO3
|
1
|
| 1 |
Ki = 2.12 nM
|
|
|
|
CP0418821
|
1,3-Bis-{2-[3-(2-amino-ethyl)-1H-indol-5-yloxy]-ethyl}-urea
Show/Hide
|
C25H32N6O3
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0492326
|
2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-N-{2-[3-(2-amino-ethyl)-1H-indol-5-yloxy]-ethyl}-acetamide
Show/Hide
|
C24H29N5O3
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0429497
|
6-[2-[4-[[4-fluoro-3-(2-methoxyethoxy)phenyl]methyl]piperidin-1-yl]ethyl]-2,3-dihydrochromen-4-one
Show/Hide
|
C26H32FNO4
|
1
|
| 1 |
Ki = 2.25 nM
|
|
|
|
CP0420914
|
N-[3-[2-(4-phenylpiperazin-1-yl)ethyl]phenyl]-2-pyridin-4-ylacetamide
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
Ki = 2.26 nM
|
|
|
|
CP0568518
|
4-[(2-chloro-5-methoxyphenyl)methyl]-1-(2-phenylethyl)piperidine
Show/Hide
|
C21H26ClNO
|
1
|
| 1 |
Ki = 2.27 nM
|
|
|
|
CP0416279
|
3-(5-methoxy-1H-indol-3-yl)-1-[4-[4-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]pyrrolidine-2,5-dione
Show/Hide
|
C31H36N4O4
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0523490
|
6-[2-[4-[[3-(2-methoxyethoxy)phenyl]methyl]piperidin-1-yl]ethyl]-2,3-dihydrochromen-4-one
Show/Hide
|
C26H33NO4
|
1
|
| 1 |
Ki = 2.41 nM
|
|
|
|
CP0466083
|
8-acetyl-7-[4-[4-(3-bromophenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C26H29BrN2O4
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0118796
|
Cariprazine
Show/Hide
|
C21H32Cl2N4O
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0377072
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-(2-phenylethyl)piperidine
Show/Hide
|
C21H26BrNO
|
1
|
| 1 |
Ki = 2.72 nM
|
|
|
|
CP0387562
|
6-[2-[4-[[4-chloro-3-(2-methoxyethoxy)phenyl]methyl]piperidin-1-yl]ethyl]-2,3-dihydrochromen-4-one
Show/Hide
|
C26H32ClNO4
|
1
|
| 1 |
Ki = 2.81 nM
|
|
|
|
CP0469089
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-[2-(3-chlorophenyl)ethyl]piperidine
Show/Hide
|
C21H25BrClNO
|
1
|
| 1 |
Ki = 2.93 nM
|
|
|
|
CP0429433
|
2-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]-3H-quinazolin-4-one
Show/Hide
|
C22H25ClN4O
|
1
|
| 1 |
Ki = 2.96 nM
|
|
|
|
CP0388479
|
3-[5-[4-(2-ethoxyphenyl)piperazin-1-yl]pentyl]-2-methylquinazolin-4-one
Show/Hide
|
C26H34N4O2
|
1
|
| 1 |
Ki = 2.99 nM
|
|
|
|
CP0436652
|
N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-3-fluorobenzenesulfonamide
Show/Hide
|
C23H25ClFN3O2S
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0852533
|
2-(4-(3-(4,7-dimethyl-2-oxo-2H-chromen-5-yloxy)propyl)piperazin-1-yl)benzonitrile
Show/Hide
|
C25H27N3O3
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0906607
|
4,7-dimethyl-5-{3-[4-(2-fluorophenyl)piperazin-1-yl]propoxy}coumarin
Show/Hide
|
C24H27FN2O3
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0420641
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-[2-(2-methoxyphenyl)ethyl]piperidine
Show/Hide
|
C22H28BrNO2
|
1
|
| 1 |
Ki = 3.03 nM
|
|
|
|
CP0394123
|
3-(5-fluoro-1H-indol-3-yl)-1-[4-[4-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]pyrrolidine-2,5-dione
Show/Hide
|
C30H33FN4O3
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0413623
|
3-[5-[4-(3-chlorophenyl)piperazin-1-yl]pentyl]-5,6-dimethylthieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C23H29ClN4OS
|
1
|
| 1 |
Ki = 3.23 nM
|
|
|
|
CP0445939
|
8-acetyl-7-[3-[4-(3-bromophenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
|
C25H27BrN2O4
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0450872
|
8-acetyl-7-[4-[4-(3,5-dimethylphenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C28H34N2O4
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0391059
|
2-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]-3H-[1]benzothiolo[3,2-d]pyrimidin-4-one
Show/Hide
|
C24H25ClN4OS
|
1
|
| 1 |
Ki = 3.84 nM
|
|
|
|
CP0481824
|
3-[6-(4-phenylpiperazin-1-yl)hexyl]-1,3-benzoxazol-2-one
Show/Hide
|
C23H29N3O2
|
1
|
| 1 |
Ki = 3.96 nM
|
|
|
|
CP0403765
|
2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(1'-{2-[3-(2-amino-ethyl)-1H-indol-5-yloxy]-acetyl}-[4,4']bipiperidinyl-1-yl)-ethanone
Show/Hide
|
C34H44N6O4
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0393441
|
N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]naphthalene-1-sulfonamide
Show/Hide
|
C27H28ClN3O2S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0393455
|
N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-1-sulfonamide
Show/Hide
|
C25H24ClN3O2S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0408139
|
N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-3-hydroxybenzenesulfonamide
Show/Hide
|
C22H24ClN3O3S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0864710
|
5-(3-(4-(2,3-dichlorophenyl)piperazin-1-yl)propoxy)-4,7-dimethyl-2H-chromen-2-one
Show/Hide
|
C24H26Cl2N2O3
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0436395
|
2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-N-(4-{2-[3-(2-amino-ethyl)-1H-indol-5-yloxy]-acetylamino}-phenyl)-acetamide
Show/Hide
|
C30H32N6O4
|
1
|
| 1 |
Ki = 4.06 nM
|
|
|
|
CP0469088
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-[2-(2-chlorophenyl)ethyl]piperidine
Show/Hide
|
C21H25BrClNO
|
1
|
| 1 |
Ki = 4.08 nM
|
|
|
|
CP0403731
|
2-(5-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxymethyl]-benzyloxy}-1H-indol-3-yl)-ethylamine
Show/Hide
|
C28H30N4O2
|
1
|
| 1 |
Ki = 4.3 nM
|
|
|
|
CP0443953
|
N-[3-[2-(4-phenylpiperazin-1-yl)ethyl]phenyl]-2-pyridin-2-ylacetamide
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
Ki = 4.73 nM
|
|
|
|
CP0857137
|
6-acetyl-4,7-dimethyl-5-(4-(4-(pyrazin-2-yl)piperazin-1-yl)butoxy)-2H-chromen-2-one
Show/Hide
|
C25H30N4O4
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0037955
|
METHIOTHEPIN
Show/Hide
|
C20H24N2S2
|
1
|
| 1 |
Ki = 4.8 nM
|
|
|
|
CP0510173
|
4-[(2-bromo-5-methoxyphenyl)methyl]-1-(2-naphthalen-1-ylethyl)piperidine
Show/Hide
|
C25H28BrNO
|
1
|
| 1 |
Ki = 4.81 nM
|
|
|
|
CP0387086
|
1-[4-[4-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-3-(5-methoxy-1H-indol-3-yl)pyrrolidine-2,5-dione
Show/Hide
|
C30H33FN4O3
|
1
|
| 1 |
Ki = 4.9 nM
|
|
|
|
CP0463415
|
N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-3-methylbenzenesulfonamide
Show/Hide
|
C23H26ClN3O2S
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0475024
|
N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]naphthalene-1-sulfonamide
Show/Hide
|
C26H26ClN3O2S
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0429504
|
6-[2-[4-[[4-bromo-3-(2-methoxyethoxy)phenyl]methyl]piperidin-1-yl]ethyl]-2,3-dihydrochromen-4-one
Show/Hide
|
C26H32BrNO4
|
1
|
| 1 |
Ki = 5.05 nM
|
|
|
|
CP0422047
|
3-methyl-2-[4-(4-phenylpiperazin-1-yl)butyl]-[1]benzothiolo[3,2-d]pyrimidin-4-one
Show/Hide
|
C25H28N4OS
|
1
|
| 1 |
Ki = 5.15 nM
|
|
|
|
CP0120218
|
3-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]quinazolin-4-one
Show/Hide
|
C22H25ClN4O
|
1
|
| 1 |
Ki = 5.3 nM
|
|
|
|
CP0416080
|
8-acetyl-7-[4-[4-(2,5-dimethylphenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
|
C28H34N2O4
|
1
|
| 1 |
Ki = 5.4 nM
|
|
|
|
CP0476521
|
1-phenyl-3-[3-[2-(4-phenylpiperazin-1-yl)ethyl]phenyl]urea
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C25H28N4O
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1
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| 1 |
Ki = 5.78 nM
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CP0403349
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N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-3-methylbenzenesulfonamide
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C24H28ClN3O2S
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1
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| 1 |
Ki = 6 nM
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CP0877295
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5-(3-(4-(3-methoxyphenyl)piperazin-1-yl)propoxy)-4,7-dimethyl-2H-chromen-2-one
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C25H30N2O4
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1
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| 1 |
Ki = 6 nM
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CP0376986
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4-[(2-fluoro-5-methoxyphenyl)methyl]-1-(2-phenylethyl)piperidine
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C21H26FNO
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1
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| 1 |
Ki = 6.04 nM
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CP0417892
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5-(4-(2-methoxyphenyl)piperazin-1-yl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)pentanamide
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C26H35N3O2
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1
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| 1 |
Ki = 6.05 nM
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CP0393444
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N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3-hydroxybenzenesulfonamide
Show/Hide
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C21H22ClN3O3S
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1
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| 1 |
Ki = 6.1 nM
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CP0379152
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3-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]-1,3-benzothiazol-2-one
Show/Hide
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C21H24ClN3OS
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1
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| 1 |
Ki = 6.13 nM
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CP0413622
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3-[5-[4-(3-chlorophenyl)piperazin-1-yl]pentyl]quinazolin-4-one
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C23H27ClN4O
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1
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| 1 |
Ki = 6.28 nM
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CP0422317
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1-[4-[4-(1H-indol-3-yl)piperidin-1-yl]butyl]-3-(5-methoxy-1H-indol-3-yl)pyrrolidine-2,5-dione
Show/Hide
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C30H34N4O3
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1
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| 1 |
Ki = 6.3 nM
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CP0446567
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4-[(2-bromo-5-methoxyphenyl)methyl]-1-[2-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)ethyl]piperidine
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C23H27BrClNO3
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1
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| 1 |
Ki = 6.46 nM
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CP0417895
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3-[4-[4-(3-chlorophenyl)piperazin-1-yl]butyl]-6-fluoro-1,3-dihydroindol-2-one
Show/Hide
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C22H25ClFN3O
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1
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| 1 |
Ki = 6.7 nM
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CP0864705
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4,7-dimethyl-5-(4-(4-(pyrazin-2-yl)piperazin-1-yl)butoxy)-2H-chromen-2-one
Show/Hide
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C23H28N4O3
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1
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| 1 |
Ki = 6.7 nM
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CP0455867
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CAS_441351-20-8
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C28H36N4O2S
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1
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| 1 |
Ki = 6.7 nM
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CP0408275
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4-[5-[4-(2-ethoxyphenyl)piperazin-1-yl]pentoxy]-6-phenylpyrimidine
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C27H34N4O2
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1
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| 1 |
Ki = 6.96 nM
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CP0474916
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N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]naphthalene-2-sulfonamide
Show/Hide
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C27H28ClN3O2S
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1
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| 1 |
Ki = 7 nM
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CP0857136
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6-acetyl-4,7-dimethyl-5-{4-[4-(4-chlorophenyl)piperazin-1-yl]butoxy}coumarin
Show/Hide
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C27H31ClN2O4
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1
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| 1 |
Ki = 7 nM
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CP0394125
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3-(5-fluoro-1H-indol-3-yl)-1-[4-[4-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]pyrrolidine-2,5-dione
Show/Hide
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C29H30F2N4O2
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1
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| 1 |
Ki = 7 nM
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CP0379318
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3-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-1,3-benzothiazol-2-one
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C23H29N3O2S
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1
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| 1 |
Ki = 7.13 nM
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CP0451856
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2-[5-[4-(3-chlorophenyl)piperazin-1-yl]pentyl]-3H-quinazolin-4-one
Show/Hide
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C23H27ClN4O
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1
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| 1 |
Ki = 7.33 nM
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CP0393442
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3-chloro-N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]benzenesulfonamide
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C21H21Cl2N3O2S
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1
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| 1 |
Ki = 7.4 nM
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CP0443955
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1-[3-[2-(4-phenylpiperazin-1-yl)ethyl]phenyl]-3-pyridin-2-ylurea
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C24H27N5O
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1
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| 1 |
Ki = 7.53 nM
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CP0456071
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6-[2-[4-[[3-(2-methoxyethoxy)-4-methylphenyl]methyl]piperidin-1-yl]ethyl]-2,3-dihydrochromen-4-one
Show/Hide
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C27H35NO4
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1
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| 1 |
Ki = 7.72 nM
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CP0852534
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5-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-4,7-dimethyl-2H-chromen-2-one
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C25H28Cl2N2O3
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1
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| 1 |
Ki = 8 nM
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CP0459429
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4-(2-chlorophenyl)-2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C31H35ClN4O2
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1
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| 1 |
Ki = 8 nM
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CP0408274
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3-[5-[4-(3-chlorophenyl)piperazin-1-yl]pentyl]-2-methylquinazolin-4-one
Show/Hide
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C24H29ClN4O
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1
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| 1 |
Ki = 8.21 nM
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CP0441180
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2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-N-(3-{2-[3-(2-amino-ethyl)-1H-indol-5-yloxy]-acetylamino}-propyl)-acetamide
Show/Hide
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C27H34N6O4
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1
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| 1 |
Ki = 8.6 nM
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CP0429500
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6-[2-[4-[[4-iodo-3-(2-methoxyethoxy)phenyl]methyl]piperidin-1-yl]ethyl]-2,3-dihydrochromen-4-one
Show/Hide
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C26H32INO4
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1
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| 1 |
Ki = 8.76 nM
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CP0490835
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8-acetyl-4-methyl-7-[3-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]propoxy]chromen-2-one
Show/Hide
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C26H27F3N2O4
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1
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| 1 |
Ki = 8.8 nM
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CP0413409
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4-chloro-N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]benzenesulfonamide
Show/Hide
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C22H23Cl2N3O2S
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1
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| 1 |
Ki = 9 nM
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CP0847217
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4-[2-Bromo-5-(2-methoxyethoxy)benzyl]-1-[2-(7-chloro-2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]piperidine hydrochloride
Show/Hide
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C25H32BrCl2NO4
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1
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| 1 |
Ki = 9.4 nM
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CP0394213
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2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-{2-[3-(2-amino-ethyl)-1H-indol-5-yloxy]-ethyl}-piperazin-1-yl)-ethanone
Show/Hide
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C28H36N6O3
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1
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| 1 |
Ki = 9.5 nM
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CP0449404
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2-{5-[2-(4-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-ethyl}-piperazin-1-yl)-ethoxy]-1H-indol-3-yl}-ethylamine
Show/Hide
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C28H38N6O2
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1
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| 1 |
Ki = 9.5 nM
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CP0024732
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5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzofuran-2-carboxylic acid amide
Show/Hide
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C26H27N5O2
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1
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| 1 |
Ki = 9.7 nM
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CP0479795
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2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-N-[4-(4-{2-[3-(2-amino-ethyl)-1H-indol-5-yloxy]-acetyl}-piperazin-1-yl)-phenyl]-acetamide
Show/Hide
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C34H39N7O4
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1
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| 1 |
Ki = 9.8 nM
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CP0408135
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N-[4-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]naphthalene-2-sulfonamide
Show/Hide
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C27H28FN3O2S
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1
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| 1 |
Ki = 10 nM
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CP0408140
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4-chloro-N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]benzenesulfonamide
Show/Hide
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C23H25Cl2N3O2S
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1
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| 1 |
Ki = 10 nM
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CP0413408
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N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-3-hydroxybenzenesulfonamide
Show/Hide
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C23H26ClN3O3S
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1
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| 1 |
Ki = 10 nM
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CP0513529
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N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-3-fluorobenzenesulfonamide
Show/Hide
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C22H23ClFN3O2S
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1
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| 1 |
Ki = 10 nM
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CP0483453
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3-[4-[4-(2-methylphenyl)piperazin-1-yl]butyl]-1,3-benzothiazol-2-one
Show/Hide
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C22H27N3OS
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1
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| 1 |
Ki = 10.36 nM
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CP0408136
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3-chloro-N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]benzenesulfonamide
Show/Hide
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C22H23Cl2N3O2S
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1
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| 1 |
Ki = 11 nM
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CP0456368
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8-acetyl-7-[3-[4-(4-chlorophenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
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C25H27ClN2O4
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1
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| 1 |
Ki = 11 nM
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CP0560081
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8-acetyl-4-methyl-7-[4-[4-[2-(trifluoromethyl)phenyl]piperazin-1-yl]butoxy]chromen-2-one
Show/Hide
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C27H29F3N2O4
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1
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| 1 |
Ki = 11 nM
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CP0862349
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6-acetyl-4,7-dimethyl-5-(3-(4-(pyrazin-2-yl)piperazin-1-yl)propoxy)-2H-chromen-2-one
Show/Hide
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C24H28N4O4
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1
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| 1 |
Ki = 11 nM
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CP0520768
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6-[2-[4-[[4-bromo-3-(2-methoxyethoxy)phenyl]methyl]piperidin-1-yl]ethyl]-2,3-dihydro-1,4lambda6-benzoxathiine 4,4-dioxide
Show/Hide
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C25H32BrNO5S
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1
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| 1 |
Ki = 11.3 nM
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CP0399460
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3-[5-[4-(2-methoxyphenyl)piperazin-1-yl]pentyl]-1,3-benzoxazol-2-one
Show/Hide
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C23H29N3O3
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1
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| 1 |
Ki = 11.86 nM
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CP0393439
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N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-4-fluorobenzenesulfonamide
Show/Hide
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C22H23ClFN3O2S
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1
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| 1 |
Ki = 12 nM
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CP0520767
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7-[2-[4-[[4-bromo-3-(2-methoxyethoxy)phenyl]methyl]piperidin-1-yl]ethyl]-3,4-dihydro-2H-naphthalen-1-one
Show/Hide
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C27H34BrNO3
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1
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| 1 |
Ki = 12.4 nM
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CP0416278
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3-(5-fluoro-1H-indol-3-yl)-1-[4-[4-(1H-indol-3-yl)piperidin-1-yl]butyl]pyrrolidine-2,5-dione
Show/Hide
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C29H31FN4O2
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1
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| 1 |
Ki = 13 nM
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CP0384283
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4-(4-fluorophenyl)-2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C31H35FN4O2
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1
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| 1 |
Ki = 13 nM
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CP0471745
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2-[4-[4-(5-chloro-2-methoxyphenyl)piperazin-1-yl]butyl]-3H-thieno[3,2-d]pyrimidin-4-one
Show/Hide
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C21H25ClN4O2S
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1
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| 1 |
Ki = 13.4 nM
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CP0466085
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8-acetyl-7-[3-[4-(2,5-dimethylphenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
Show/Hide
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C27H32N2O4
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1
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| 1 |
Ki = 14 nM
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CP0446075
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2-(5-{2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-ethoxy}-1H-indol-3-yl)-ethylamine
Show/Hide
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C22H26N4O2
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1
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| 1 |
Ki = 14.3 nM
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CP0862350
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6-acetyl-5-(4-(4-(3-methoxyphenyl)piperazin-1-yl)butoxy)-4,7-dimethyl-2H-chromen-2-one
Show/Hide
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C28H34N2O5
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1
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| 1 |
Ki = 15 nM
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CP0423149
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4-(2-fluorophenyl)-2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C31H35FN4O2
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1
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| 1 |
Ki = 15 nM
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CP0429431
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5,6-dimethyl-2-[5-(4-phenylpiperazin-1-yl)pentyl]-3H-thieno[2,3-d]pyrimidin-4-one
Show/Hide
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C23H30N4OS
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1
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| 1 |
Ki = 15.2 nM
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CP0549301
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1-[4-(3-chlorophenyl)piperazin-1-yl]-3-[4-(2-ethoxyphenyl)piperazin-1-yl]propan-1-one
Show/Hide
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C25H33ClN4O2
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1
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| 1 |
Ki = 15.2 nM
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CP0420642
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4-[(2-bromo-5-propan-2-yloxyphenyl)methyl]-1-[2-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)ethyl]piperidine
Show/Hide
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C25H31BrClNO3
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1
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| 1 |
Ki = 15.9 nM
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CP0393443
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4-chloro-N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]benzenesulfonamide
Show/Hide
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C21H21Cl2N3O2S
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1
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| 1 |
Ki = 16 nM
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CP0519756
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4-[[4-bromo-3-(2-methoxyethoxy)phenyl]methyl]-1-[2-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]piperidine
Show/Hide
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C25H32BrNO4
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1
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| 1 |
Ki = 16 nM
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CP0429434
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5,6-dimethyl-3-[5-(4-phenylpiperazin-1-yl)pentyl]thieno[2,3-d]pyrimidin-4-one
Show/Hide
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C23H30N4OS
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1
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| 1 |
Ki = 16.1 nM
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CP0422048
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2-[5-(4-phenylpiperazin-1-yl)pentyl]-3H-[1]benzothiolo[3,2-d]pyrimidin-4-one
Show/Hide
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C25H28N4OS
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1
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| 1 |
Ki = 16.4 nM
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CP0851574
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Methysergide maleate
Show/Hide
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C25H31N3O6
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1
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| 1 |
Ki = 17 nM
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CP0445786
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4-[5-[4-(3-chlorophenyl)piperazin-1-yl]pentoxy]-6-phenylpyrimidine
Show/Hide
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C25H29ClN4O
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1
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| 1 |
Ki = 17.4 nM
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CP0531207
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3-[5-[4-(3-chlorophenyl)piperazin-1-yl]pentyl]-6-phenylpyrimidin-4-one
Show/Hide
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C25H29ClN4O
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1
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| 1 |
Ki = 17.8 nM
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CP0135602
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[3-(2-aminoethyl)-1H-indol-5-yl] trifluoromethanesulfonate
Show/Hide
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C11H11F3N2O3S
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1
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| 1 |
Ki = 18 nM
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CP0408137
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N-[2-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-2-sulfonamide
Show/Hide
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C25H24ClN3O2S
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1
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| 1 |
Ki = 18 nM
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CP0555765
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2-methyl-3-[5-(4-phenylpiperazin-1-yl)pentyl]quinazolin-4-one
Show/Hide
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C24H30N4O
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1
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| 1 |
Ki = 18.6 nM
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CP0456070
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4-[[4-bromo-3-(2-methoxyethoxy)phenyl]methyl]-1-[2-(3,4-dihydro-2H-chromen-7-yl)ethyl]piperidine
Show/Hide
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C26H34BrNO3
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1
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| 1 |
Ki = 19 nM
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CP0379150
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3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1,3-benzoxazol-2-one
Show/Hide
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C22H27N3O3
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1
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| 1 |
Ki = 19.22 nM
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CP0398219
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3-[5-(4-phenylpiperazin-1-yl)pentyl]-1,3-benzoxazol-2-one
Show/Hide
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C22H27N3O2
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1
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| 1 |
Ki = 19.22 nM
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CP0387563
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6-[2-[4-[[4-ethyl-3-(2-methoxyethoxy)phenyl]methyl]piperidin-1-yl]ethyl]-2,3-dihydrochromen-4-one
Show/Hide
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C28H37NO4
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1
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| 1 |
Ki = 19.3 nM
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CP0394215
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2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-(4-{2-[3-(2-amino-ethyl)-1H-indol-5-yloxy]-acetyl}-piperazin-1-yl)-ethanone
Show/Hide
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C28H34N6O4
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1
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| 1 |
Ki = 20 nM
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CP0463656
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N-[4-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-4-fluorobenzenesulfonamide
Show/Hide
|
C23H25ClFN3O2S
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1
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| 1 |
Ki = 21 nM
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CP0490098
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methyl 3-[5-(4-phenylpiperazin-1-yl)pentanoylamino]thiophene-2-carboxylate
Show/Hide
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C21H27N3O3S
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1
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| 1 |
Ki = 21.2 nM
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CP0036796
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[3-[2-(dipropylamino)ethyl]-1H-indol-5-yl] trifluoromethanesulfonate
Show/Hide
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C17H23F3N2O3S
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1
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| 1 |
Ki = 23 nM
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CP0570560
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4-(4-chlorophenyl)-2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C32H37ClN4O3
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1
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| 1 |
Ki = 23 nM
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CP0420645
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4-[(2-bromo-5-ethoxyphenyl)methyl]-1-[2-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)ethyl]piperidine
Show/Hide
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C24H29BrClNO3
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1
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| 1 |
Ki = 23.4 nM
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CP0492525
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3-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-1,3-benzothiazol-2-one
Show/Hide
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C22H27N3O2S
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1
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| 1 |
Ki = 24.58 nM
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CP0566533
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2-methyl-4-[5-(4-phenylpiperazin-1-yl)pentoxy]quinazoline
Show/Hide
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C24H30N4O
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1
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| 1 |
Ki = 24.7 nM
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CP0540702
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2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-4-(2-methoxyphenyl)-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C32H38N4O3
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1
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| 1 |
Ki = 25 nM
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CP0504359
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3-[5-[4-(2-ethoxyphenyl)piperazin-1-yl]pentyl]-6-phenylpyrimidin-4-one
Show/Hide
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C27H34N4O2
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1
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| 1 |
Ki = 25.9 nM
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CP0557263
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3-[5-[4-(4-chlorophenyl)piperazin-1-yl]pentyl]-5,6-dimethylthieno[2,3-d]pyrimidin-4-one
Show/Hide
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C23H29ClN4OS
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1
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| 1 |
Ki = 26.4 nM
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CP0332330
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[3-[2-(diethylamino)ethyl]-1H-indol-5-yl] trifluoromethanesulfonate
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C15H19F3N2O3S
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1
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| 1 |
Ki = 27 nM
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CP0468855
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N-[3-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
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C26H26FN3O2S
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1
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| 1 |
Ki = 27 nM
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CP0423146
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2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-4-phenyl-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C31H36N4O2
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1
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| 1 |
Ki = 27 nM
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CP0488917
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8-acetyl-7-[4-[4-(4-chlorophenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
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C26H29ClN2O4
|
1
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| 1 |
Ki = 28 nM
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CP0570563
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2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(2-fluorophenyl)-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C31H34F2N4O2
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1
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| 1 |
Ki = 28 nM
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CP0481834
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3-[5-(4-phenylpiperazin-1-yl)pentyl]quinazolin-4-one
Show/Hide
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C23H28N4O
|
1
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| 1 |
Ki = 28.9 nM
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CP0451830
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4-[(3-methoxyphenyl)methyl]-1-(2-phenylethyl)piperidine
Show/Hide
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C21H27NO
|
1
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| 1 |
Ki = 29.3 nM
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CP0559132
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3-[7-(4-phenylpiperazin-1-yl)heptyl]-1,3-benzoxazol-2-one
Show/Hide
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C24H31N3O2
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1
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| 1 |
Ki = 29.78 nM
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CP0423148
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4-(4-chlorophenyl)-2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C31H35ClN4O2
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1
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| 1 |
Ki = 30 nM
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CP0435657
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2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-fluorophenyl)-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C31H34F2N4O2
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1
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| 1 |
Ki = 31 nM
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CP0941755
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6-(2-(4-(4-bromo-3-(2-methoxyethoxy)benzyl)piperidin-1-yl)ethyl)chroman-4-ol
Show/Hide
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C26H34BrNO4
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1
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| 1 |
Ki = 32.8 nM
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CP0911152
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6-acetyl-4,7-dimethyl-5-(4-(4-(4-nitrophenyl)piperazin-1-yl)butoxy)-2H-chromen-2-one
Show/Hide
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C27H31N3O6
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1
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| 1 |
Ki = 33 nM
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CP0382566
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4-phenyl-6-[5-(4-phenylpiperazin-1-yl)pentoxy]pyrimidine
Show/Hide
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C25H30N4O
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1
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| 1 |
Ki = 33.5 nM
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CP0437876
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3-[4-(3-chlorophenyl)piperazin-1-yl]-1-(4-phenylpiperazin-1-yl)propan-1-one
Show/Hide
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C23H29ClN4O
|
1
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| 1 |
Ki = 33.5 nM
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CP0480970
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N-[2-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-2-sulfonamide
Show/Hide
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C25H24FN3O2S
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1
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| 1 |
Ki = 36 nM
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CP0530822
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2-[4-(4-phenylpiperazin-1-yl)butyl]-3H-quinazolin-4-one
Show/Hide
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C22H26N4O
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1
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| 1 |
Ki = 36.6 nM
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CP0429430
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5,6-dimethyl-2-[4-(4-phenylpiperazin-1-yl)butyl]-3H-thieno[2,3-d]pyrimidin-4-one
Show/Hide
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C22H28N4OS
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1
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| 1 |
Ki = 37.4 nM
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CP0489018
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8-acetyl-4-methyl-7-[4-(4-pyrazin-2-ylpiperazin-1-yl)butoxy]chromen-2-one
Show/Hide
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C24H28N4O4
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1
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| 1 |
Ki = 38 nM
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CP0422308
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3-[5-(4-phenylpiperazin-1-yl)pentanoylamino]thiophene-2-carboxamide
Show/Hide
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C20H26N4O2S
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1
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| 1 |
Ki = 38.7 nM
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CP0477293
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2-[5-[4-(3-chlorophenyl)piperazin-1-yl]pentanoylamino]benzamide
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C22H27ClN4O2
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1
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| 1 |
Ki = 39.6 nM
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CP0196504
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[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl] trifluoromethanesulfonate
Show/Hide
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C13H15F3N2O3S
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1
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| 1 |
Ki = 40 nM
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CP0379157
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benzimidazolone scaffold, 15d
Show/Hide
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C21H26N4O2
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1
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| 1 |
Ki = 40 nM
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CP0549465
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2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(2-methoxyphenyl)-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C32H37FN4O3
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1
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| 1 |
Ki = 40 nM
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CP0471903
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2-[4-(4-phenylpiperazin-1-yl)butyl]-3H-thieno[3,2-d]pyrimidin-4-one
Show/Hide
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C20H24N4OS
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1
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| 1 |
Ki = 40.4 nM
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CP0490087
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6-phenyl-2-[4-(4-phenylpiperazin-1-yl)butyl]-3H-thieno[3,2-d]pyrimidin-4-one
Show/Hide
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C26H28N4OS
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1
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| 1 |
Ki = 40.4 nM
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CP0538393
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2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-methoxyphenyl)-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C32H37FN4O3
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1
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| 1 |
Ki = 42 nM
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CP0387561
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7-[2-[4-[[4-bromo-3-(2-methoxyethoxy)phenyl]methyl]piperidin-1-yl]ethyl]-2,3-dihydrochromen-4-one
Show/Hide
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C26H32BrNO4
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1
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| 1 |
Ki = 42.8 nM
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CP0456069
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4-[[4-bromo-3-(2-methoxyethoxy)phenyl]methyl]-1-[2-(3,4-dihydro-2H-chromen-6-yl)ethyl]piperidine
Show/Hide
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C26H34BrNO3
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1
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| 1 |
Ki = 43.1 nM
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CP0443956
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1-phenyl-4-(2-phenylethyl)piperazine
Show/Hide
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C18H22N2
|
1
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| 1 |
Ki = 43.2 nM
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CP0537737
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2-[5-(4-phenylpiperazin-1-yl)pentyl]-3H-quinazolin-4-one
Show/Hide
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C23H28N4O
|
1
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| 1 |
Ki = 43.5 nM
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CP0387565
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6-[2-[4-[[3-bromo-5-(2-methoxyethoxy)phenyl]methyl]piperidin-1-yl]ethyl]-2,3-dihydrochromen-4-one
Show/Hide
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C26H32BrNO4
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1
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| 1 |
Ki = 44.3 nM
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CP0439674
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1-{4-[4-(1-Naphthyl)piperazin-1-yl]butyl}-1,3-dihydro-2H-indol-2-one
Show/Hide
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C26H29N3O
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1
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| 1 |
Ki = 47 nM
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CP0575494
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4-(2-chlorophenyl)-2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C31H34ClFN4O2
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1
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| 1 |
Ki = 47 nM
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CP0465873
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1-[2-[4-(1H-indol-3-yl)piperidin-1-yl]ethyl]-3-(5-methoxy-1H-indol-3-yl)pyrrolidine-2,5-dione
Show/Hide
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C28H30N4O3
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1
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| 1 |
Ki = 48.7 nM
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CP0416079
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8-acetyl-7-[4-[4-(3-fluorophenyl)piperazin-1-yl]butoxy]-4-methylchromen-2-one
Show/Hide
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C26H29FN2O4
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1
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| 1 |
Ki = 50 nM
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CP0384285
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4-(2-chlorophenyl)-2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C32H37ClN4O3
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1
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| 1 |
Ki = 50 nM
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CP0423124
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2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-methylphenyl)-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C32H38N4O2
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1
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| 1 |
Ki = 50 nM
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CP0413621
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3-[5-[4-(4-chlorophenyl)piperazin-1-yl]pentyl]quinazolin-4-one
Show/Hide
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C23H27ClN4O
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1
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| 1 |
Ki = 51.5 nM
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CP0465870
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3-(5-methoxy-1H-indol-3-yl)-1-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]pyrrolidine-2,5-dione
Show/Hide
|
C31H36N4O4
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1
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| 1 |
Ki = 52 nM
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CP0459430
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2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-methoxyphenyl)-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C33H40N4O4
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1
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| 1 |
Ki = 52 nM
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CP0549464
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2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-methoxyphenyl)-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C32H38N4O3
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1
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| 1 |
Ki = 52 nM
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CP0376944
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4-[5-[4-(4-chlorophenyl)piperazin-1-yl]pentoxy]-2-methylquinazoline
Show/Hide
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C24H29ClN4O
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1
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| 1 |
Ki = 52.1 nM
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CP0090070
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6-{4-[2-(methylsulfanyl)phenyl]piperazin-1-yl}-N-(1,2,3,4-tetrahydronaphthalen-1-yl)hexanamide
Show/Hide
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C27H37N3OS
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1
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| 1 |
Ki = 52.7 nM
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CP0429432
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2-[5-[4-(4-chlorophenyl)piperazin-1-yl]pentyl]-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one
Show/Hide
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C23H29ClN4OS
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1
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| 1 |
Ki = 53.9 nM
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CP0387560
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4-[[3-bromo-5-(2-methoxyethoxy)phenyl]methyl]-1-[2-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]piperidine
Show/Hide
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C25H32BrNO4
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1
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| 1 |
Ki = 57.8 nM
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CP0864704
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5-(4-(4-(4-chlorophenyl)piperazin-1-yl)butoxy)-4,7-dimethyl-2H-chromen-2-one
Show/Hide
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C25H29ClN2O3
|
1
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| 1 |
Ki = 60 nM
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CP0549457
|
2-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]-4-(2-methylphenyl)-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C32H38N4O2
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1
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| 1 |
Ki = 62 nM
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CP0462037
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N-[3-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-3-methylbenzenesulfonamide
Show/Hide
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C23H26FN3O2S
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1
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| 1 |
Ki = 66 nM
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CP0423145
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2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(2-methylphenyl)-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C33H40N4O3
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1
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| 1 |
Ki = 66 nM
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CP0440229
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3-(5-methoxy-1H-indol-3-yl)-1-[3-[4-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]propyl]pyrrolidine-2,5-dione
Show/Hide
|
C30H34N4O4
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1
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| 1 |
Ki = 68.7 nM
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CP0489827
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6-[2-[4-[[3-(2-methoxyethoxy)-4-propan-2-ylphenyl]methyl]piperidin-1-yl]ethyl]-2,3-dihydrochromen-4-one
Show/Hide
|
C29H39NO4
|
1
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| 1 |
Ki = 69.9 nM
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CP0436651
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N-[3-[4-(5-chloro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C26H26ClN3O2S
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1
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| 1 |
Ki = 70 nM
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CP0474914
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N-[2-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3-methylbenzenesulfonamide
Show/Hide
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C23H26ClN3O2S
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1
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| 1 |
Ki = 70 nM
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CP0429498
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7-[2-[4-[[4-bromo-3-(2-methoxyethoxy)phenyl]methyl]piperidin-1-yl]ethyl]-3,4-dihydro-2H-1-benzoxepin-5-one
Show/Hide
|
C27H34BrNO4
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1
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| 1 |
Ki = 71.9 nM
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CP0418285
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3-[4-(3,4-dihydro-1H-isoquinolin-2-yl)butyl]-1,3-benzothiazol-2-one
Show/Hide
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C20H22N2OS
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1
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| 1 |
Ki = 74.92 nM
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CP0488676
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2-[4-[4-(4-chlorophenyl)piperazin-1-yl]butyl]-3H-quinazolin-4-one
Show/Hide
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C22H25ClN4O
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1
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| 1 |
Ki = 75.3 nM
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CP0534220
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4-(4-fluorophenyl)-2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
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C32H37FN4O3
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1
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| 1 |
Ki = 76 nM
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CP0422320
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3-(1H-indol-3-yl)-1-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]pyrrolidine-2,5-dione
Show/Hide
|
C30H34N4O3
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1
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| 1 |
Ki = 78 nM
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CP0420755
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3-[4-(2-ethoxyphenyl)piperazin-1-yl]-1-(4-phenylpiperazin-1-yl)propan-1-one
Show/Hide
|
C25H34N4O2
|
1
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| 1 |
Ki = 81.8 nM
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CP0481825
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3-[4-[4-(4-chlorophenyl)piperazin-1-yl]butyl]-1,3-benzothiazol-2-one
Show/Hide
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C21H24ClN3OS
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1
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| 1 |
Ki = 83.33 nM
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CP0408273
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4-[5-[4-(4-chlorophenyl)piperazin-1-yl]pentoxy]-6-phenylpyrimidine
Show/Hide
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C25H29ClN4O
|
1
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| 1 |
Ki = 90.3 nM
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CP0379147
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3-[4-(4-phenylpiperazin-1-yl)butyl]-1,3-benzoxazol-2-one
Show/Hide
|
C21H25N3O2
|
1
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| 1 |
Ki = 90.33 nM
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CP0489016
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8-acetyl-4-methyl-7-[4-[4-(4-nitrophenyl)piperazin-1-yl]butoxy]chromen-2-one
Show/Hide
|
C26H29N3O6
|
1
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| 1 |
Ki = 92 nM
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CP0476518
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N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]phenyl]-2-pyridin-2-ylacetamide
Show/Hide
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C25H28N4O
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1
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| 1 |
Ki = 95.3 nM
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CP0483452
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3-[5-(4-phenylpiperazin-1-yl)pentyl]-1,3-benzothiazol-2-one
Show/Hide
|
C22H27N3OS
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1
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| 1 |
Ki = 95.66 nM
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CP0393440
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N-[4-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-3-methylbenzenesulfonamide
Show/Hide
|
C24H28FN3O2S
|
1
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| 1 |
Ki = 96 nM
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CP0445783
|
3-[5-[4-(4-chlorophenyl)piperazin-1-yl]pentyl]-2-methylquinazolin-4-one
Show/Hide
|
C24H29ClN4O
|
1
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| 1 |
Ki = 100 nM
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CP0437877
|
3-(4-benzylpiperazin-1-yl)-1-[4-(3-chlorophenyl)piperazin-1-yl]propan-1-one
Show/Hide
|
C24H31ClN4O
|
1
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| 1 |
Ki = 101 nM
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CP0455660
|
2-[4-(4-benzylpiperidin-1-yl)butyl]-3H-thieno[3,2-d]pyrimidin-4-one
Show/Hide
|
C22H27N3OS
|
1
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| 1 |
Ki = 102 nM
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CP0435656
|
2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]-4-phenyl-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C32H38N4O3
|
1
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| 1 |
Ki = 102 nM
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CP0570562
|
2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-4-phenyl-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C31H35FN4O2
|
1
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| 1 |
Ki = 105 nM
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CP0472938
|
N-[2-[4-(5-fluoro-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]-3-methylbenzenesulfonamide
Show/Hide
|
C22H24FN3O2S
|
1
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| 1 |
Ki = 110 nM
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CP0494035
|
N-[3-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]-3-methylbenzenesulfonamide
Show/Hide
|
C24H28ClN3O2S
|
1
|
| 1 |
Ki = 110 nM
|
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|
|
CP0376943
|
6-phenyl-3-[5-(4-phenylpiperazin-1-yl)pentyl]pyrimidin-4-one
Show/Hide
|
C25H30N4O
|
1
|
| 1 |
Ki = 111 nM
|
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|
|
CP0542518
|
2-[5-[4-(3-chlorophenyl)piperazin-1-yl]pentyl]-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C23H29ClN4OS
|
1
|
| 1 |
Ki = 114 nM
|
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CP0433461
|
2-[5-[4-(4-chlorophenyl)piperazin-1-yl]pentyl]-3H-quinazolin-4-one
Show/Hide
|
C23H27ClN4O
|
1
|
| 1 |
Ki = 116 nM
|
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CP0394192
|
3-(1H-indol-3-yl)-1-[4-[3-(1H-indol-3-yl)piperidin-1-yl]butyl]pyrrolidine-2,5-dione
Show/Hide
|
C29H32N4O2
|
1
|
| 1 |
Ki = 122 nM
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CP0476519
|
N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]phenyl]-2-pyridin-4-ylacetamide
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
Ki = 122.5 nM
|
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CP0476520
|
1-[4-[2-(4-phenylpiperazin-1-yl)ethyl]phenyl]-3-pyridin-2-ylurea
Show/Hide
|
C24H27N5O
|
1
|
| 1 |
Ki = 125.8 nM
|
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CP0275909
|
N-[4-[4-[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]piperazin-1-yl]phenyl]acetamide
Show/Hide
|
C24H29N5O3
|
1
|
| 1 |
Ki = 134 nM
|
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CP0415977
|
3-amino-2-[4-(4-phenylpiperazin-1-yl)butyl]-[1]benzothiolo[3,2-d]pyrimidin-4-one
Show/Hide
|
C24H27N5OS
|
1
|
| 1 |
Ki = 134 nM
|
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|
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CP0538392
|
2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(2-methylphenyl)-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C32H37FN4O2
|
1
|
| 1 |
Ki = 142 nM
|
|
|
|
CP0460659
|
1,3-bis[4-(3-chlorophenyl)piperazin-1-yl]propan-1-one
Show/Hide
|
C23H28Cl2N4O
|
1
|
| 1 |
Ki = 142 nM
|
|
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CP0547534
|
3-(5-fluoro-1H-indol-3-yl)-1-[3-[4-(1H-indol-3-yl)piperidin-1-yl]propyl]pyrrolidine-2,5-dione
Show/Hide
|
C28H29FN4O2
|
1
|
| 1 |
Ki = 143.2 nM
|
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CP0504744
|
2-[5-(4-benzylpiperidin-1-yl)pentyl]-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C25H33N3OS
|
1
|
| 1 |
Ki = 148 nM
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CP0864707
|
6-acetyl-4,7-dimethyl-5-(3-(4-(pyridin-4-yl)piperazin-1-yl)propoxy)-2H-chromen-2-one
Show/Hide
|
C25H29N3O4
|
1
|
| 1 |
Ki = 154 nM
|
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CP0394130
|
3-(5-fluoro-1H-indol-3-yl)-1-[3-[4-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]propyl]pyrrolidine-2,5-dione
Show/Hide
|
C29H31FN4O3
|
1
|
| 1 |
Ki = 157 nM
|
|
|
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CP0911941
|
6-acetyl-4,7-dimethyl-5-(3-(4-(4-nitrophenyl)piperazin-1-yl)propoxy)-2H-chromen-2-one
Show/Hide
|
C26H29N3O6
|
1
|
| 1 |
Ki = 159 nM
|
|
|
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CP0416576
|
N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]phenyl]-2-pyridin-3-ylacetamide
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
Ki = 159.8 nM
|
|
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CP0891133
|
5-(3-(4-(4-chlorophenyl)piperazin-1-yl)propoxy)-4,7-dimethyl-2H-chromen-2-one
Show/Hide
|
C24H27ClN2O3
|
1
|
| 1 |
Ki = 161 nM
|
|
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CP0445632
|
3-[5-[4-(4-chlorophenyl)piperazin-1-yl]pentyl]-6-phenylpyrimidin-4-one
Show/Hide
|
C25H29ClN4O
|
1
|
| 1 |
Ki = 167 nM
|
|
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CP0168742
|
2a-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)-2a,3,4,5-tetrahydrobenzo[cd]indol-2(1H)-one
Show/Hide
|
C26H30N2O
|
1
|
| 1 |
Ki = 169 nM
|
|
|
|
CP0447151
|
N-[4-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]-3-methylbenzenesulfonamide
Show/Hide
|
C25H30ClN3O2S
|
1
|
| 1 |
Ki = 170 nM
|
|
|
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CP0390364
|
8-acetyl-4-methyl-7-(3-morpholin-4-ylpropoxy)chromen-2-one
Show/Hide
|
C19H23NO5
|
1
|
| 1 |
Ki = 180 nM
|
|
|
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CP0455866
|
1-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-3-(1H-indol-3-yl)pyrrolidine-2,5-dione
Show/Hide
|
C29H31FN4O2
|
1
|
| 1 |
Ki = 183 nM
|
|
|
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CP0857134
|
4,7-dimethyl-5-(3-(4-(pyrazin-2-yl)piperazin-1-yl)propoxy)-2H-chromen-2-one
Show/Hide
|
C22H26N4O3
|
1
|
| 1 |
Ki = 186 nM
|
|
|
|
CP0386711
|
8-acetyl-4-methyl-7-[4-(4-pyridin-4-ylpiperazin-1-yl)butoxy]chromen-2-one
Show/Hide
|
C25H29N3O4
|
1
|
| 1 |
Ki = 190 nM
|
|
|
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CP0440230
|
1-[3-[4-(1H-indol-3-yl)piperidin-1-yl]propyl]-3-(5-methoxy-1H-indol-3-yl)pyrrolidine-2,5-dione
Show/Hide
|
C29H32N4O3
|
1
|
| 1 |
Ki = 204.1 nM
|
|
|
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CP0462144
|
3-[5-(4-benzylpiperazin-1-yl)pentyl]-5,6-dimethylthieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C24H32N4OS
|
1
|
| 1 |
Ki = 211 nM
|
|
|
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CP0383842
|
1-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)butyl]-1,3-dihydro-2Hindol-2-one
Show/Hide
|
C21H24N2O
|
1
|
| 1 |
Ki = 219 nM
|
|
|
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CP0465872
|
1-[2-[4-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]ethyl]-3-(5-methoxy-1H-indol-3-yl)pyrrolidine-2,5-dione
Show/Hide
|
C28H29FN4O3
|
1
|
| 1 |
Ki = 222 nM
|
|
|
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CP0436488
|
1-[4-[2-(4-phenylpiperazin-1-yl)ethyl]phenyl]-3-pyridin-4-ylurea
Show/Hide
|
C24H27N5O
|
1
|
| 1 |
Ki = 226.8 nM
|
|
|
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CP0384284
|
2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-methylphenyl)-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C32H37FN4O2
|
1
|
| 1 |
Ki = 233 nM
|
|
|
|
CP0534219
|
4-(2-fluorophenyl)-2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C32H37FN4O3
|
1
|
| 1 |
Ki = 236 nM
|
|
|
|
CP0384286
|
2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(2-methoxyphenyl)-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C33H40N4O4
|
1
|
| 1 |
Ki = 239 nM
|
|
|
|
CP0422073
|
3-(5-methoxy-1H-indol-3-yl)-1-[2-[4-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]ethyl]pyrrolidine-2,5-dione
Show/Hide
|
C29H32N4O4
|
1
|
| 1 |
Ki = 240 nM
|
|
|
|
CP0422319
|
1-[3-[4-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]propyl]-3-(5-methoxy-1H-indol-3-yl)pyrrolidine-2,5-dione
Show/Hide
|
C29H31FN4O3
|
1
|
| 1 |
Ki = 246 nM
|
|
|
|
CP0871828
|
6-acetyl-5-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)-4,7-dimethyl-2H-chromen-2-one
Show/Hide
|
C27H30Cl2N2O4
|
1
|
| 1 |
Ki = 250 nM
|
|
|
|
CP0891132
|
6-acetyl-4,7-dimethyl-5-(4-morpholinobutoxy)-2H-chromen-2-one
Show/Hide
|
C21H27NO5
|
1
|
| 1 |
Ki = 250 nM
|
|
|
|
CP0489828
|
4-[[4-bromo-3-(2-methoxyethoxy)phenyl]methyl]-1-[2-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)ethyl]piperidine
Show/Hide
|
C25H31BrClNO4
|
1
|
| 1 |
Ki = 251 nM
|
|
|
|
CP0520930
|
8-acetyl-4-methyl-7-[3-(4-pyrazin-2-ylpiperazin-1-yl)propoxy]chromen-2-one
Show/Hide
|
C23H26N4O4
|
1
|
| 1 |
Ki = 253 nM
|
|
|
|
CP0435655
|
4-(4-chlorophenyl)-2-[4-[3-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]butyl]-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C31H34ClFN4O2
|
1
|
| 1 |
Ki = 259 nM
|
|
|
|
CP0477292
|
3-[5-(4-benzylpiperazin-1-yl)pentyl]quinazolin-4-one
Show/Hide
|
C24H30N4O
|
1
|
| 1 |
Ki = 268 nM
|
|
|
|
CP0460661
|
1,3-bis(4-phenylpiperazin-1-yl)propan-1-one
Show/Hide
|
C23H30N4O
|
1
|
| 1 |
Ki = 272 nM
|
|
|
|
CP0408138
|
N-[2-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]ethyl]naphthalene-2-sulfonamide
Show/Hide
|
C26H26ClN3O2S
|
1
|
| 1 |
Ki = 280 nM
|
|
|
|
CP0460660
|
1-[4-(3-chlorophenyl)piperazin-1-yl]-3-[4-(4-chlorophenyl)piperazin-1-yl]propan-1-one
Show/Hide
|
C23H28Cl2N4O
|
1
|
| 1 |
Ki = 302 nM
|
|
|
|
CP0489017
|
8-acetyl-4-methyl-7-(4-morpholin-4-ylbutoxy)chromen-2-one
Show/Hide
|
C20H25NO5
|
1
|
| 1 |
Ki = 303 nM
|
|
|
|
CP0864709
|
6-acetyl-4,7-dimethyl-5-(4-(4-(pyridin-4-yl)piperazin-1-yl)butoxy)-2H-chromen-2-one
Show/Hide
|
C26H31N3O4
|
1
|
| 1 |
Ki = 308 nM
|
|
|
|
CP0465874
|
3-(5-fluoro-1H-indol-3-yl)-1-[2-[4-(1H-indol-3-yl)piperidin-1-yl]ethyl]pyrrolidine-2,5-dione
Show/Hide
|
C27H27FN4O2
|
1
|
| 1 |
Ki = 320 nM
|
|
|
|
CP0570561
|
2-[4-[3-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]butyl]-4-(4-methylphenyl)-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidine-1,3-dione
Show/Hide
|
C33H40N4O3
|
1
|
| 1 |
Ki = 321 nM
|
|
|
|
CP0455695
|
2-[4-(4-benzylpiperidin-1-yl)butyl]-3H-[1]benzothiolo[3,2-d]pyrimidin-4-one
Show/Hide
|
C26H29N3OS
|
1
|
| 1 |
Ki = 328 nM
|
|
|
|
CP0476423
|
3-(5-fluoro-1H-indol-3-yl)-1-[3-[4-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]propyl]pyrrolidine-2,5-dione
Show/Hide
|
C28H28F2N4O2
|
1
|
| 1 |
Ki = 336 nM
|
|
|
|
CP0005653
|
(3-[2-(dimethylamino)ethyl]-1H-indol-5-yl)-N-methylmethanesulfonamide
Show/Hide
|
C14H21N3O2S
|
2
|
| 1 |
Ki = 341 nM
|
|
|
| 2 |
Ki = 440 nM
|
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|
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CP0477761
|
1,5-bis(4-phenylpiperazin-1-yl)pentan-1-one
Show/Hide
|
C25H34N4O
|
1
|
| 1 |
Ki = 350 nM
|
|
|
|
CP0433460
|
2-[5-(4-benzylpiperazin-1-yl)pentyl]-6-methyl-3H-thieno[2,3-d]pyrimidin-4-one
Show/Hide
|
C23H30N4OS
|
1
|
| 1 |
Ki = 363 nM
|
|
|
|
CP0391061
|
2-[3-(4-phenylpiperazin-1-yl)propylsulfanyl]-3H-[1]benzothiolo[3,2-d]pyrimidin-4-one
Show/Hide
|
C23H24N4OS2
|
1
|
| 1 |
Ki = 369 nM
|
|
|
|
CP0864706
|
4,7-dimethyl-5-(4-(4-(pyridin-4-yl)piperazin-1-yl)butoxy)-2H-chromen-2-one
Show/Hide
|
C24H29N3O3
|
1
|
| 1 |
Ki = 389 nM
|
|
|
|
CP0432339
|
1-[4-[2-(4-phenylpiperazin-1-yl)ethyl]phenyl]-3-pyridin-3-ylurea
Show/Hide
|
C24H27N5O
|
1
|
| 1 |
Ki = 397.9 nM
|
|
|
|
CP0891123
|
4,7-dimethyl-5-(3-(4-(pyridin-4-yl)piperazin-1-yl)propoxy)-2H-chromen-2-one
Show/Hide
|
C23H27N3O3
|
1
|
| 1 |
Ki = 450 nM
|
|
|
|
CP0481334
|
benzimidazolone scaffold, 15m
Show/Hide
|
C22H27ClN4O
|
1
|
| 1 |
Ki = 454 nM
|
|
|
|
CP0387564
|
4-[[2-bromo-3-(2-methoxyethoxy)phenyl]methyl]-1-[2-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)ethyl]piperidine
Show/Hide
|
C25H31BrClNO4
|
1
|
| 1 |
Ki = 468 nM
|
|
|
|
CP0379233
|
1-[4-[(4aR,8aS)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]butyl]-3H-indol-2-one
Show/Hide
|
C21H30N2O
|
1
|
| 1 |
Ki = 470 nM
|
|
|
|
CP0447152
|
N-[4-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]butyl]naphthalene-2-sulfonamide
Show/Hide
|
C28H30ClN3O2S
|
1
|
| 1 |
Ki = 470 nM
|
|
|
|
CP0422309
|
2-[4-(4-benzylpiperazin-1-yl)butyl]-3H-thieno[3,2-d]pyrimidin-4-one
Show/Hide
|
C21H26N4OS
|
1
|
| 1 |
Ki = 489 nM
|
|
|
|
CP0379231
|
1-[5-[(4aR,8aS)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]pentyl]-3H-indol-2-one
Show/Hide
|
C22H32N2O
|
1
|
| 1 |
Ki = 491 nM
|
|
|
|
CP0462036
|
N-[3-[4-(5-chloro-2-methyl-1H-indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]propyl]naphthalene-2-sulfonamide
Show/Hide
|
C27H28ClN3O2S
|
1
|
| 1 |
Ki = 520 nM
|
|
|
|
CP0418761
|
1-[5-(3,4-dihydro-1H-isoquinolin-2-yl)pentyl]-3H-indol-2-one
Show/Hide
|
C22H26N2O
|
1
|
| 1 |
Ki = 523 nM
|
|
|
|
CP0456068
|
4-[[3-bromo-5-(2-methoxyethoxy)phenyl]methyl]-1-[2-(6-chloro-2,3-dihydro-1,4-benzodioxin-7-yl)ethyl]piperidine
Show/Hide
|
C25H31BrClNO4
|
1
|
| 1 |
Ki = 546 nM
|
|
|
|
CP0519973
|
8-acetyl-4-methyl-7-[3-(4-pyridin-4-ylpiperazin-1-yl)propoxy]chromen-2-one
Show/Hide
|
C24H27N3O4
|
1
|
| 1 |
Ki = 556 nM
|
|
|
|
CP0379232
|
1-[6-(3,4-dihydro-1H-isoquinolin-2-yl)hexyl]-3H-indol-2-one
Show/Hide
|
C23H28N2O
|
1
|
| 1 |
Ki = 576 nM
|
|
|
|
CP0162156
|
3-(4-fluorophenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
|
C27H34FN5S
|
1
|
| 1 |
Ki = 587 nM
|
|
|
|
CP0386713
|
8-acetyl-4-methyl-7-[3-[4-(4-nitrophenyl)piperazin-1-yl]propoxy]chromen-2-one
Show/Hide
|
C25H27N3O6
|
1
|
| 1 |
Ki = 613 nM
|
|
|
|
CP0418284
|
3-[4-(4-benzylpiperazin-1-yl)butyl]-1,3-benzothiazol-2-one
Show/Hide
|
C22H27N3OS
|
1
|
| 1 |
Ki = 695.11 nM
|
|
|
|
CP0394128
|
3-(5-fluoro-1H-indol-3-yl)-1-[2-[4-(5-fluoro-1H-indol-3-yl)piperidin-1-yl]ethyl]pyrrolidine-2,5-dione
Show/Hide
|
C27H26F2N4O2
|
1
|
| 1 |
Ki = 700 nM
|
|
|
|
CP0098320
|
2-(2-methoxyphenyl)-8-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,8-diazaspiro[4.5]decane
Show/Hide
|
C27H35N5OS
|
1
|
| 1 |
Ki = 724 nM
|
|
|
|
CP0567738
|
3-[5-(4-benzylpiperazin-1-yl)pentyl]-6-phenylpyrimidin-4-one
Show/Hide
|
C26H32N4O
|
1
|
| 1 |
Ki = 772 nM
|
|
|
|
CP0422307
|
2-[5-(4-benzylpiperazin-1-yl)pentyl]-3H-[1]benzothiolo[3,2-d]pyrimidin-4-one
Show/Hide
|
C26H30N4OS
|
1
|
| 1 |
Ki = 808 nM
|
|
|
|
CP0852530
|
4,7-dimethyl-5-(4-(4-(4-nitrophenyl)piperazin-1-yl)butoxy)-2H-chromen-2-one
Show/Hide
|
C25H29N3O5
|
1
|
| 1 |
Ki = 809 nM
|
|
|
|
CP0852529
|
6-acetyl-4,7-dimethyl-5-[3-(morpholin-4-yl)propoxy]coumarin
Show/Hide
|
C20H25NO5
|
1
|
| 1 |
Ki = 850 nM
|
|
|
|
CP0552163
|
2-[5-(4-benzylpiperidin-1-yl)pentyl]-3H-[1]benzothiolo[3,2-d]pyrimidin-4-one
Show/Hide
|
C27H31N3OS
|
1
|
| 1 |
Ki = 856 nM
|
|
|
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CP0420912
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2-phenyl-N-[4-[2-(4-phenylpiperazin-1-yl)ethyl]phenyl]acetamide
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C26H29N3O
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1
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| 1 |
Ki = 902.6 nM
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CP0379148
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3-[4-(4-phenylpiperazin-1-yl)butyl]-1,3-benzothiazol-2-one
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C21H25N3OS
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1
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| 1 |
Ki = 913 nM
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CP0003459
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3-(2-methoxyphenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
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C28H37N5OS
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1
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| 1 |
Ki = 931 nM
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CP0460663
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3-(benzylamino)-1-(4-phenylpiperazin-1-yl)propan-1-one
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C20H25N3O
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1
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| 1 |
Ki = 938 nM
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CP0468649
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2-[4-(4-benzylpiperazin-1-yl)butyl]-3H-[1]benzothiolo[3,2-d]pyrimidin-4-one
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C25H28N4OS
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1
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| 1 |
Ki = 964 nM
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CP0422306
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2-[3-(4-benzylpiperidin-1-yl)propylsulfanyl]-3H-[1]benzothiolo[3,2-d]pyrimidin-4-one
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C25H27N3OS2
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1
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| 1 |
Ki = 993 nM
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CP0567737
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4-[5-(4-benzylpiperazin-1-yl)pentoxy]-6-phenylpyrimidine
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C26H32N4O
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1
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| 1 |
Ki = 1032 nM
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CP0437881
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1-[4-(3-chlorophenyl)piperazin-1-yl]-3-(4-phenylpiperazin-1-yl)propan-1-one
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C23H29ClN4O
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1
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| 1 |
Ki = 1074 nM
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CP0422311
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2-[4-(4-phenylpiperazin-1-yl)butyl]-3H-[1]benzothiolo[3,2-d]pyrimidin-4-one
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C24H26N4OS
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1
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| 1 |
Ki = 1148 nM
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CP0857132
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4,7-dimethyl-5-(3-(4-(4-nitrophenyl)piperazin-1-yl)propoxy)-2H-chromen-2-one
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C24H27N3O5
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1
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| 1 |
Ki = 1210 nM
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CP0905188
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4,7-dimethyl-5-(3-morpholinopropoxy)-2H-chromen-2-one
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C18H23NO4
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1
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| 1 |
Ki = 1304 nM
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CP0416078
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8-acetyl-7-[3-[4-(3-fluorophenyl)piperazin-1-yl]propoxy]-4-methylchromen-2-one
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C25H27FN2O4
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1
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| 1 |
Ki = 1350 nM
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CP0494807
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3-[4-(4-chlorophenyl)piperazin-1-yl]-1-(4-phenylpiperazin-1-yl)propan-1-one
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C23H29ClN4O
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1
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| 1 |
Ki = 1684 nM
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CP0436487
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1-phenyl-3-[4-[2-(4-phenylpiperazin-1-yl)ethyl]phenyl]urea
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C25H28N4O
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1
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| 1 |
Ki = 2264 nM
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CP0490089
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2-[3-(4-benzylpiperazin-1-yl)propylsulfanyl]-3H-[1]benzothiolo[3,2-d]pyrimidin-4-one
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C24H26N4OS2
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1
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| 1 |
Ki = 2306 nM
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CP0869881
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4,7-dimethyl-5-(4-morpholinobutoxy)-2H-chromen-2-one
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C19H25NO4
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1
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| 1 |
Ki = 3500 nM
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CP0494808
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N-benzyl-3-(benzylamino)propanamide
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C17H20N2O
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1
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| 1 |
Ki = 3750 nM
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CP0096286
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(R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidin-1-ylsulfonyl)phenol
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C18H28N2O3S
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2
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| 1 |
Ki = 9024 nM
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| 2 |
Ki > 10000 nM
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CP0449397
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2-[3-(2-Amino-ethyl)-1H-indol-5-yloxy]-1-piperazin-1-yl-ethanone
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C16H22N4O2
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1
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| 1 |
Ki > 100 nM
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CP0052721
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1-[(E)-6-(3,4-dihydro-1H-isoquinolin-2-yl)hex-3-enyl]-3H-indol-2-one
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C23H26N2O
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1
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| 1 |
Ki > 1000 nM
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CP0375370
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1-[(E)-6-[(4aR,8aS)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]hex-3-enyl]-3H-indol-2-one
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C23H32N2O
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1
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| 1 |
Ki > 1000 nM
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CP0400269
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1-[7-[(4aR,8aS)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]heptyl]-3H-indol-2-one
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C24H36N2O
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1
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| 1 |
Ki > 1000 nM
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CP0455895
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1-[7-(3,4-dihydro-1H-isoquinolin-2-yl)heptyl]-3H-indol-2-one
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C24H30N2O
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1
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| 1 |
Ki > 1000 nM
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CP0056688
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(5S,6R)-5-Methyl-6-propylamino-5,6,7,8-tetrahydro-naphthalene-1-carbonitrile
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C15H20N2
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1
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| 1 |
Ki > 1786 nM
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CP0476421
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3-(5-fluoro-1H-indol-3-yl)-1-[2-[4-(5-methoxy-1H-indol-3-yl)piperidin-1-yl]ethyl]pyrrolidine-2,5-dione
Show/Hide
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C28H29FN4O3
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1
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| 1 |
Ki > 5000 nM
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