General Information of the Compound
Compound ID
CP0905961
Compound Name
SID103162960
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Structure
Formula
C23H21N3O4
Molecular Weight
403.438
Canonical SMILES
COc1cccc(-c2cnc3c(NC=O)cc(-c4ccc(OC)cc4OC)cn23)c1
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InChI
InChI=1S/C23H21N3O4/c1-28-17-6-4-5-15(9-17)21-12-24-23-20(25-14-27)10-16(13-26(21)23)19-8-7-18(29-2)11-22(19)30-3/h4-14H,1-3H3,(H,25,27)
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InChIKey
SDIPCXFAOKSWQS-UHFFFAOYSA-N
Physicochemical Property
logP
4.2624
Rotatable Bonds
7
Heavy Atom Count
30
Polar Areas
74.09
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 49795390
ChEMBL ID
CHEMBL1898535
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
Potency ~ 206 nM
   TI
   LI
   LO
   TS
Protein ID: PT06124, Paired box protein Pax-8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000097 RMG-I Homo sapiens (Human)  1
1
AC50 = 2930 nM
   TI
   LI
   LO
   TS