General Information of the Compound
| Compound ID |
CP0887654
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
N-(3-((4-acetylpiperazin-1-yl)methyl)-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyridin-6-yl)-N-(difluoromethyl)methanesulfonamide
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C22H23Cl2F2N5O3S
|
||||||||||||||||||
| Molecular Weight |
546.427
|
||||||||||||||||||
| Canonical SMILES |
CC(=O)N1CCN(Cc2c(-c3ccc(Cl)cc3Cl)nc3ccc(N(C(F)F)S(C)(=O)=O)cn23)CC1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C22H23Cl2F2N5O3S/c1-14(32)29-9-7-28(8-10-29)13-19-21(17-5-3-15(23)11-18(17)24)27-20-6-4-16(12-30(19)20)31(22(25)26)35(2,33)34/h3-6,11-12,22H,7-10,13H2,1-2H3
Show/Hide
|
||||||||||||||||||
| InChIKey |
KNKOVYGHFHGUGP-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04657, Solute carrier family 2, facilitated glucose transporter member 1
Protein ID: PT06319, Solute carrier family 2, facilitated glucose transporter member 2
Protein ID: PT06387, Solute carrier family 2, facilitated glucose transporter member 3
Protein ID: PT03440, Solute carrier family 2, facilitated glucose transporter member 4