General Information of the Compound
| Compound ID |
CP0872331
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| Compound Name |
(E)-N-Hydroxy-3-(4-oxo-3-phenethyl-3,4-dihydro-quinazolin-7-yl)-acrylamide
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| Structure |
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| Formula |
C19H17N3O3
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| Molecular Weight |
335.363
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| Canonical SMILES |
O=C(/C=C/c1ccc2c(=O)n(CCc3ccccc3)cnc2c1)NO
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| InChI |
InChI=1S/C19H17N3O3/c23-18(21-25)9-7-15-6-8-16-17(12-15)20-13-22(19(16)24)11-10-14-4-2-1-3-5-14/h1-9,12-13,25H,10-11H2,(H,21,23)/b9-7+
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| InChIKey |
VAAWIYIVFTYJRI-VQHVLOKHSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00991, Histone deacetylase 1
Protein ID: PT02410, Histone deacetylase 11
Protein ID: PT00835, Histone deacetylase 2
Protein ID: PT01213, Histone deacetylase 6
Protein ID: PT01499, Histone deacetylase 8