General Information of the Compound
Compound ID
CP0846123
Compound Name
SID49669711
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Structure
Formula
C22H28ClN3O4S
Molecular Weight
466.003
Canonical SMILES
CCOC(=O)Nc1ccc2c(c1)N(C(=O)CCN(CC)CC)c1ccccc1[S+]2[O-].Cl
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InChI
InChI=1S/C22H27N3O4S.ClH/c1-4-24(5-2)14-13-21(26)25-17-9-7-8-10-19(17)30(28)20-12-11-16(15-18(20)25)23-22(27)29-6-3;/h7-12,15H,4-6,13-14H2,1-3H3,(H,23,27);1H
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InChIKey
FUVPJPVUTNZEIF-UHFFFAOYSA-N
Physicochemical Property
logP
4.5535
Rotatable Bonds
7
Heavy Atom Count
31
Polar Areas
84.94
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
31

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 2872306
ChEMBL ID
CHEMBL1589168
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
Potency ~ 16360.1 nM
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   LI
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   TS
Protein ID: PT06124, Paired box protein Pax-8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000097 RMG-I Homo sapiens (Human)  1
1
AC50 = 7060 nM
   TI
   LI
   LO
   TS