General Information of the Compound
Compound ID
CP0709752
Compound Name
SID51087137
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Structure
Formula
C30H35ClN4O4S2
Molecular Weight
615.221
Canonical SMILES
COc1ccc(C)c2sc(N(CCCN(C)C)C(=O)c3ccc(S(=O)(=O)N4CCc5ccccc5C4)cc3)nc12.Cl
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InChI
InChI=1S/C30H34N4O4S2.ClH/c1-21-10-15-26(38-4)27-28(21)39-30(31-27)34(18-7-17-32(2)3)29(35)23-11-13-25(14-12-23)40(36,37)33-19-16-22-8-5-6-9-24(22)20-33;/h5-6,8-15H,7,16-20H2,1-4H3;1H
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InChIKey
PPTLNQZFALAMSG-UHFFFAOYSA-N
Physicochemical Property
logP
5.38062
Rotatable Bonds
9
Heavy Atom Count
41
Polar Areas
83.05
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
7
Complexity
41

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 24892208
ChEMBL ID
CHEMBL1564519
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000015 SW480 Homo sapiens (Human)  1
1
Potency ~ 3981.1 nM
   TI
   LI
   LO
   TS
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
Potency ~ 29092.9 nM
   TI
   LI
   LO
   TS
Protein ID: PT06172, Mothers against decapentaplegic homolog 3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
Potency ~ 7307.8 nM
   TI
   LI
   LO
   TS