General Information of the Compound
Compound ID
CP0696598
Compound Name
SID17412900
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Structure
Formula
C22H19N3O
Molecular Weight
341.414
Canonical SMILES
CCn1c2ccccc2c2cc(/C=N/NC(=O)c3ccccc3)ccc21
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InChI
InChI=1S/C22H19N3O/c1-2-25-20-11-7-6-10-18(20)19-14-16(12-13-21(19)25)15-23-24-22(26)17-8-4-3-5-9-17/h3-15H,2H2,1H3,(H,24,26)/b23-15+
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InChIKey
XOSCAFZLXOPHJA-HZHRSRAPSA-N
Physicochemical Property
logP
4.5783
Rotatable Bonds
4
Heavy Atom Count
26
Polar Areas
46.39
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 6871317
SID: 24741288
ChEMBL ID
CHEMBL1980018
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000015 SW480 Homo sapiens (Human)  1
1
Potency ~ 29092.9 nM
   TI
   LI
   LO
   TS
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
Potency ~ 11582.1 nM
   TI
   LI
   LO
   TS
Protein ID: PT06101, Latent membrane protein 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
AC50 = 38435 nM
   TI
   LI
   LO
   TS