General Information of the Compound
Compound ID
CP0437743
Compound Name
N-(4-chlorophenyl)sulfonyl-2-methyl-2-[4-[2-(4-phenyldiazenylphenoxy)ethyl]phenoxy]propanamide
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Formula
C30H28ClN3O5S
Molecular Weight
578.09
Canonical SMILES
CC(C)(Oc1ccc(CCOc2ccc(cc2)\N=N\c2ccccc2)cc1)C(=O)NS(=O)(=O)c1ccc(Cl)cc1
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InChI
InChI=1S/C30H28ClN3O5S/c1-30(2,29(35)34-40(36,37)28-18-10-23(31)11-19-28)39-27-14-8-22(9-15-27)20-21-38-26-16-12-25(13-17-26)33-32-24-6-4-3-5-7-24/h3-19H,20-21H2,1-2H3,(H,34,35)/b33-32+
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InChIKey
PJQDOFZHUXFGEA-ULIFNZDWSA-N
Physicochemical Property
logP
7.0394
Rotatable Bonds
11
Heavy Atom Count
40
Polar Areas
106.42
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4642691
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00910, Peroxisome proliferator-activated receptor alpha
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 210 nM
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000007 HT-29 Homo sapiens (Human)  1
1
CC50 > 24000 nM
   TI
   LI
   LO
   TS
CL000015 SW480 Homo sapiens (Human)  1
1
CC50 > 24000 nM
   TI
   LI
   LO
   TS
CL000496 AsPC-1 Homo sapiens (Human)  1
1
CC50 > 24000 nM
   TI
   LI
   LO
   TS