General Information of the Compound
Compound ID
CP0433576
Compound Name
3-(2-(furan-2-carboxamido)ethyl)benzofuran-5-carboxamide
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Structure
Formula
C16H14N2O4
Molecular Weight
298.298
Canonical SMILES
NC(=O)c1ccc2occ(CCNC(=O)c3ccco3)c2c1
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InChI
InChI=1S/C16H14N2O4/c17-15(19)10-3-4-13-12(8-10)11(9-22-13)5-6-18-16(20)14-2-1-7-21-14/h1-4,7-9H,5-6H2,(H2,17,19)(H,18,20)
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InChIKey
XSVQVVXJSFYREP-UHFFFAOYSA-N
Physicochemical Property
logP
2.0972
Rotatable Bonds
5
Heavy Atom Count
22
Polar Areas
98.47
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
22

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44593609
ChEMBL ID
CHEMBL505118
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01843, Melatonin receptor type 1A
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Protein ID: PT02174, Melatonin receptor type 1B
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Protein ID: PT02130, Ribosyldihydronicotinamide dehydrogenase [quinone]
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 67.61 nM
   TI
   LI
   LO
   TS