General Information of the Compound
| Compound ID |
CP0423436
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| Compound Name |
(+)2-(2-Methoxy-2,3-dihydro-benzo[1,4]dioxin-2-yl)-4,5-dihydro-1H-imidazole
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| Synonyms |
[3H]2-methoxyidazoxan
102575-24-6
1H-Imidazole, 2-(2,3-dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-
2-(2,3-Dihydro-2-methoxy-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole
2-(2-methoxy-2,3-dihydro-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole
2-(2-methoxy-3H-1,4-benzodioxin-2-yl)-4,5-dihydro-1H-imidazole
2-Methoxyidazoxan
2-[2-(2-methoxy-1,4-benzodioxanyl)]imidazoline
2-ethoxy-idazoxan
CHEBI:73287
CHEMBL10332
PubChem2676
RX 821001
RX 821002
RX-821002
RX821002
Spectrum_001808
[3H]2-methoxyidazoxan
[3H]RX821002
alpha-methoxyidazoxan
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| Structure |
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| Formula |
C12H14N2O3
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| Molecular Weight |
234.255
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| Canonical SMILES |
COC1(COc2ccccc2O1)C1=NCCN1
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| InChI |
InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14)
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| InChIKey |
HQGWKNGAKBPTBX-UHFFFAOYSA-N
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| CAS |
102575-24-6
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01650, Alpha-2A adrenergic receptor
Protein ID: PT02026, Alpha-2B adrenergic receptor
Protein ID: PT01598, Alpha-2C adrenergic receptor
Clinical Information about the Compound
Drug 1 ( [3H]RX821002 )
| Drug Name | [3H]RX821002 | ||
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| Target(s) |
Adrenergic receptor alpha-2C (ADRA2C)
Antagonist
Adrenergic receptor alpha-2B (ADRA2B)
Antagonist
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