General Information of the Compound
| Compound ID |
CP0381487
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| Compound Name |
N-[2-chloro-4-(pyridine-2-carbonylamino)phenyl]-1,3-thiazole-5-carboxamide
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| Structure |
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| Formula |
C16H11ClN4O2S
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| Molecular Weight |
358.81
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| Canonical SMILES |
Clc1cc(NC(=O)c2ccccn2)ccc1NC(=O)c1cncs1
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| InChI |
InChI=1S/C16H11ClN4O2S/c17-11-7-10(20-15(22)13-3-1-2-6-19-13)4-5-12(11)21-16(23)14-8-18-9-24-14/h1-9H,(H,20,22)(H,21,23)
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| InChIKey |
ANIACALCXMZPED-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02446, Metabotropic glutamate receptor 4
Protein ID: PT02199, Metabotropic glutamate receptor 4