General Information of the Compound
| Compound ID |
CP0371440
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| Compound Name |
5-chloro-1,4-dihydroquinazolin-2-amine
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| Synonyms |
109319-86-0
2-Amino-5-chlor-3,4-dihydrochinazolin
5-chloro-3,4-dihydroquinazolin-2-amine
CHEMBL401541
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| Structure |
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| Formula |
C8H8ClN3
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| Molecular Weight |
181.626
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| Canonical SMILES |
NC1=Nc2cccc(Cl)c2CN1
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| InChI |
InChI=1S/C8H8ClN3/c9-6-2-1-3-7-5(6)4-11-8(10)12-7/h1-3H,4H2,(H3,10,11,12)
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| InChIKey |
UDUQYNVUNNDSEJ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00819, 5-hydroxytryptamine receptor 1A
Protein ID: PT00827, 5-hydroxytryptamine receptor 1D
Protein ID: PT00825, 5-hydroxytryptamine receptor 2A
Protein ID: PT00939, 5-hydroxytryptamine receptor 2C
Protein ID: PT01513, 5-hydroxytryptamine receptor 5A
Protein ID: PT01354, 5-hydroxytryptamine receptor 6
Protein ID: PT00941, 5-hydroxytryptamine receptor 7
Clinical Information about the Compound
Drug 1 ( 5-chloro-3,4-dihydroquinazolin-2-amine )
| Drug Name | 5-chloro-3,4-dihydroquinazolin-2-amine | ||
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