General Information of the Compound
Compound ID
CP0228451
Compound Name
((S)-2-Amino-3-phenyl-propionylamino)-acetic acid
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Structure
Formula
C11H14N2O3
Molecular Weight
222.244
Canonical SMILES
N[C@@H](Cc1ccccc1)C(=O)NCC(O)=O
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InChI
InChI=1S/C11H14N2O3/c12-9(11(16)13-7-10(14)15)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,16)(H,14,15)/t9-/m0/s1
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InChIKey
GLUBLISJVJFHQS-VIFPVBQESA-N
Physicochemical Property
logP
-0.2428
Rotatable Bonds
5
Heavy Atom Count
16
Polar Areas
92.42
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
3
Complexity
16

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 6992304
SID: 14843685
ChEMBL ID
CHEMBL417979
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02659, Peptidyl-glycine alpha-amidating monooxygenase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000506 DMS 53 Homo sapiens (Human)  1
1
Km = 6000000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Km = 6500000 nM
Protein ID: PT02822, Solute carrier family 15 member 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000034 Caco-2 Homo sapiens (Human)  2
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
2
Ki = 200 nM
   TI
   LI
   LO
   TS
Protein ID: PT06345, Solute carrier family 15 member 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000009 LLC-PK1 Sus scrofa (Pig)  1
1
Ki = 7000 nM
   TI
   LI
   LO
   TS