General Information of the Compound
Compound ID
CP0128905
Compound Name
2-[4-(furan-2-yl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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Structure
Formula
C16H19BO3
Molecular Weight
270.137
Canonical SMILES
CC1(C)OB(OC1(C)C)c1ccc(cc1)-c1ccco1
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InChI
InChI=1S/C16H19BO3/c1-15(2)16(3,4)20-17(19-15)13-9-7-12(8-10-13)14-6-5-11-18-14/h5-11H,1-4H3
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InChIKey
PUCSCLCOEROOCP-UHFFFAOYSA-N
Physicochemical Property
logP
3.2458
Rotatable Bonds
2
Heavy Atom Count
20
Polar Areas
31.6
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
3
Complexity
20

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 18525723
ChEMBL ID
CHEMBL1952309
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01303, Endothelial lipase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C Homo sapiens (Human)  1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1900 nM
Protein ID: PT02150, Lipoprotein lipase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 35000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9600 nM