General Information of the Compound
| Compound ID |
CP0082870
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| Compound Name |
5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
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| Synonyms |
(+-)-Ethyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
(+/-)-ethylmethyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
1A Brand of Felodipine
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(2,3-dichlorophenyl)-2,6-dimethyl-, ethyl methylester
3,5-Pyridinedicarboxylic acid, 1,4-dihydro-4-(2,3-dichlorophenyl)-2,6-dimethyl-,ethyl methyl ester
3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, ethyl methyl ester
3-Ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate
3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid ethyl methyl ester
4-(2,3-dichloro-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester
4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester
5-O-ethyl 3-O-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
AE-641/11429675
AGON SR
AbZ Brand of Felodipine
Agon
Aliud Brand of Felodipine
Alphapharm Brand of Felodipine
Alpharma Brand of Felodipine
Astra Brand of Felodipine
AstraZeneca Brand of Felodipine
Aventis Brand of Felodipine
Azupharma Brand of Felodipine
BC Brand of Felodipine
Betapharm Brand of Felodipine
CGH-869
Ct Arzneimittel Brand of Felodipine
Ct-Arzneimittel Brand of Felodipine
Dl-Felodipine
Ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
F 9677
Felo Biochemie
Felo Puren
Felo-Puren
Felobeta
Felocor
Feloday
Felodipin 1A Pharma
Felodipin AL
Felodipin AZU
Felodipin AbZ
Felodipin Heumann
Felodipin Stada
Felodipin dura
Felodipin ratiopharm
Felodipin von ct
Felodipin-ratiopharm
Felodipina
Felodipina [INN-Spanish]
Felodipine
Felodipine (JAN/USP/INN)
Felodipine [USAN:BAN:INN]
Felodipine [USAN:INN:BAN]
Felodipinum
Felodipinum [INN-Latin]
Felodur
FelodurER
Felogamma
Felogard
Fensel
Flodil
H 154 82
H 154-82
H 154/82
H 15482
H-154/82
Heumann Brand of Felodipine
Heumann, Felodipin
Hexal Brand of Felodipine
Hoechst Brand of Felodipine
Hydac
Lexxel
Logimax
Merck dura Brand of Felodipine
Modip
Munobal
Munobal Retard
Penedil
Perfudal
Pharmaceutica Astra Brand of Felodipine
Pharmacia Spain Brandof Felodipine
Plandil
Plendil
Plendil (TN)
Plendil Depottab
Plendil ER
Plendil Retard
Plendil, Renedil, Feloday, Felodipine
Preslow
Prevex
Promed Brand of Felodipine
Ratiopharm Brand of Felodipine
Renedil
Splendil
Stadapharm Brand of Felodipine
TheraPharm Brand of Felodipine
Worwag Brand of Felodipine
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| Structure |
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| Formula |
C18H19Cl2NO4
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| Molecular Weight |
384.259
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| Canonical SMILES |
CCOC(=O)C1=C(C)NC(C)=C(C1c1cccc(Cl)c1Cl)C(=O)OC
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| InChI |
InChI=1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3
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| InChIKey |
RZTAMFZIAATZDJ-UHFFFAOYSA-N
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| CAS |
72509-76-3
86189-69-7
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01546, ATP-dependent translocase ABCB1
Protein ID: PT04542, Bile salt export pump
Protein ID: PT00905, Cytochrome P450 2C9
Protein ID: PT01552, Nuclear receptor subfamily 1 group I member 2
Protein ID: PT04880, Nuclear receptor subfamily 1 group I member 2
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
Clinical Information about the Compound