General Information of the Compound
Compound ID
CP0081817
Compound Name
CHEBI:16704
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Synonyms
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
1-beta-D-ribofuranosylpyrimidine-2,4(1H,3H)-dione
58-96-8
AI3-52690
C9H12N2O6
CHEBI:16704
DRTQHJPVMGBUCF-XVFCMESISA-N
EINECS 200-407-5
MLS000069625
SMR000058222
UNII-WHI7HQ7H85
Uracil riboside
Uracil-1-beta-d-ribofuranoside
Urd
Uridin
Uridine
WHI7HQ7H85
b-Uridine
beta-Uridine
d-uridine
uridine
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Structure
Formula
C9H12N2O6
Molecular Weight
244.203
Canonical SMILES
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O
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InChI
InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
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InChIKey
DRTQHJPVMGBUCF-XVFCMESISA-N
CAS
68184-15-6
21231-59-4
12693-39-9
Physicochemical Property
logP
-2.8519
Rotatable Bonds
2
Heavy Atom Count
17
Polar Areas
124.78
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
7
Complexity
17

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 6029
SID: 15221017
ChEMBL ID
CHEMBL100259
DrugBank ID
DB02745
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000015 SW480
 Cell Line Info 
Homo sapiens (Human)  1
1
Potency ~ 1258.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT06194, Uridine-cytidine kinase 1
 Protein Info 
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000148 Huh-7
 Cell Line Info 
Homo sapiens (Human)  1
1
Km = 407000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( Uridine )
Drug Name Uridine
Indication
Depression
Approved
Target(s)
Thymidine phosphorylase (TYMP)
 Target Info 
Inhibitor