General Information of the Compound
| Compound ID |
CP0050781
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| Compound Name |
5'-(N-ethyl-N-isopropyl)amiloride
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| Synonyms |
1154-25-2
3-Amino-N-(aminoiminomethyl)-6-chloro-5-(ethyl(1-methylethyl)amino)pyrazinecarboxamide
3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide
5'-(N-ethyl-N-isopropyl)amiloride
5-(Ethylisopropyl)amiloride
5-(N-Ethyl-N-isopropyl) Amiloride
5-(N-Ethyl-N-isopropyl)amiloride
5-(N-ethyl-N-isopropyl)-Amiloride
C11H18ClN7O
CHEMBL517986
EIPA
Ethyl isopropyl amiloride
Ethylisopropylamiloride
N-Amidino-3-amino-5-ethylisopropylamino-6-chloropyrazine carboxamide
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| Structure |
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| Formula |
C11H18ClN7O
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| Molecular Weight |
299.766
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| Canonical SMILES |
CCN(C(C)C)c1nc(N)c(nc1Cl)C(=O)NC(N)=N
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| InChI |
InChI=1S/C11H18ClN7O/c1-4-19(5(2)3)9-7(12)16-6(8(13)17-9)10(20)18-11(14)15/h5H,4H2,1-3H3,(H2,13,17)(H4,14,15,18,20)
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| InChIKey |
QDERNBXNXJCIQK-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
Protein ID: PT06124, Paired box protein Pax-8
Protein ID: PT04400, Sodium/hydrogen exchanger 1
Protein ID: PT04309, Sodium/hydrogen exchanger 3
Protein ID: PT02731, Sodium/hydrogen exchanger 5
Clinical Information about the Compound