General Information of the Compound
| Compound ID |
CP0034960
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| Compound Name |
1,3,4-Thiadiazole-2-sulfonamide, 6
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| Synonyms |
CL-5343
1,3,4-Thiadiazole-2-sulfonamide, 5-amino-
1,3,4-Thiadiazole-5-sulfonamide, 2-amino-
1,3,4-thiadiazole-2-sulfonamide 15
14949-00-9
2-Amino-1,3,4-thiadiazole-5-sulfonamide
5-Amino-1,3,4-thiadiazole-2-sulfonamide
5-Amino-TDSNH2
5-amino-1,3,4-thiadiazole-2-sulfonamide
AC1L382D
AC1Q6UUX
Acetazolamide Impurity D
BDBM10868
CHEMBL265674
CL 5343
CL-5343
CTK4C6227
Carbonic anhydrase inhibitors (cancer/epilepsy/glaucoma/obesity)
Carbonic anhydrase inhibitors (cancer/epilepsy/glaucoma/obesity), University of Florence/ULS
Carbonic anhydrase inhibitors, Universita degli Studi di Firenze
DTXSID10164324
F687N81LIZ
MolPort-022-374-081
NSC 22979
NSC-22979
NSC22979
PubChem15758
SCHEMBL282413
Sulfonamide CA inhibitors, Universita degli Studi di Firenze
Sulfonamide CA inhibitors, University of Florence
Tio-urasin
UNII-F687N81LIZ
VGMVBPQOACUDRU-UHFFFAOYSA-N
ZINC16969869
aromatic/heteroaromatic
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| Structure |
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| Formula |
C2H4N4O2S2
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| Molecular Weight |
180.214
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| Canonical SMILES |
Nc1nnc(s1)S(N)(=O)=O
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| InChI |
InChI=1S/C2H4N4O2S2/c3-1-5-6-2(9-1)10(4,7)8/h(H2,3,5)(H2,4,7,8)
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| InChIKey |
VGMVBPQOACUDRU-UHFFFAOYSA-N
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| CAS |
14949-00-9
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Clinical Information about the Compound
Drug 1 ( CL-5343 )
| Drug Name | CL-5343 | ||
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| Company | Universita degli Studi di Firenze | ||
| Indication | |||
| Target(s) |
Carbonic anhydrase I (CA-I)
Inhibitor
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