General Information of the Compound
| Compound ID |
CP0002800
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| Compound Name |
1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea
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| Synonyms |
1-((p-(2-(5-Chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea
1-(p-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea
5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide
5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
Abbenclamide
Adiab
Apo-Glibenclamide
Azuglucon
Bastiverit
Benclamin
Betanase
Betanese 5
Calabren
Cytagon
Daonil
Daonil (TN)
Debtan
Dia-basan
Diabeta
Diabeta (TN)
Diabiphage
Dibelet
Duraglucon
Euclamin
Euglucan
Euglucon
Euglucon (TN)
Euglucon 5
Euglucon N
Euglykon
G 0639
GBN 5
Gen-Glybe
Gewaglucon
Gilemal
Glamide
Glibadone
Gliban
Gliben
Gliben-Puren N
Glibenbeta
Glibenclamid AL
Glibenclamid Basics
Glibenclamid Fabra
Glibenclamid Genericon
Glibenclamid Heumann
Glibenclamid Riker M
Glibenclamid Riker MGlibenclamid-Cophar
Glibenclamid-Ratiopharm
Glibenclamida
Glibenclamida [INN-Spanish]
Glibenclamide
Glibenclamide (JP15/INN)
Glibenclamidum
Glibenclamidum [INN-Latin]
Glibenil
Glibens
Glibesyn
Glibet
Glibetic
Glibil
Gliboral
Glicem
Glidiabet
Glimel
Glimide
Glimidstata
Glisulin
Glitisol
Glubate
Gluben
Gluco-Tablimen
Glucobene
Glucohexal
Glucolon
Glucomid
Glucoremed
Glucoven
Glyben
Glybenclamide
Glybenzcyclamide
Glyburide
Glyburide (USP)
Glyburide (micronized)
Glyburide [USAN]
Glycolande
Glycomin
Glynase
Glynase (TN)
HB 419
HB 420
HB-419
HB-420
HB419
HB420
Hemi-Daonil
Hexaglucon
Humedia
Lederglib
Libanil
Lisaglucon
Maninil
Med-Glionil
Melix
Micronase
Micronase (TN)
Micronized glyburide
Miglucan
N-(4-(2-(5-Chloro-2-methoxybenzamido)ethyl)phenylsulfonyl)-N'-cyclohexylurea
N-p-[2-(5-Chloro-2-methoxybenzamido)-ethyl]benzene-sulfonyl-N-cyclohexylurea
N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N'-cyclohexylurea
Nadib
Neogluconin
Norglicem 5
Normoglucon
Novo-Glyburide
Orabetic
Pira
Praeciglucon
PresTab
Prodiabet
Renabetic
Semi-Daonil (TN)
Semi-Euglucon
Semi-Gliben-Puren N
Semi-daonil
Sugril
Suraben
Tiabet
U 26452
U-26452
UR 606
Yuglucon
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| Structure |
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| Formula |
C23H28ClN3O5S
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| Molecular Weight |
494.013
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| Canonical SMILES |
COc1ccc(Cl)cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1
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| InChI |
InChI=1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29)
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| InChIKey |
ZNNLBTZKUZBEKO-UHFFFAOYSA-N
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| CAS |
10238-21-8
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03222, ATP-binding cassette sub-family C member 3
Protein ID: PT05334, ATP-binding cassette sub-family C member 4
Protein ID: PT04542, Bile salt export pump
Protein ID: PT06651, Bile salt export pump
Protein ID: PT02042, Cystic fibrosis transmembrane conductance regulator
Protein ID: PT00905, Cytochrome P450 2C9
Protein ID: PT00897, Potassium voltage-gated channel subfamily H member 2
Protein ID: PT06206, Solute carrier family 22 member 7
Protein ID: PT03566, Solute carrier organic anion transporter family member 1B1
Clinical Information about the Compound