Compound ID |
Compound Name |
Compound Formula |
CP0003145
|
(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
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|
C27H44O3
|
1
|
1 |
IC50 = 21070 nM
|
|
|
CP0006113
|
4-[3-[4-(benzenesulfonylmethoxy)-3-methylphenyl]pentan-3-yl]-N-[2-(diethylamino)ethyl]-1-ethylpyrrole-2-carboxamide
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|
C32H45N3O4S
|
1
|
1 |
IC50 = 4690 nM
|
|
|
CP0008907
|
N-[2-(diethylamino)ethyl]-1-ethyl-5-[3-[3-methyl-4-(methylsulfanylmethoxy)phenyl]pentan-3-yl]pyrrole-2-carboxamide
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|
C27H43N3O2S
|
1
|
1 |
IC50 = 5130 nM
|
|
|
CP0008908
|
1-ethyl-5-[3-[4-(2-hydroxy-3,3-dimethylbutoxy)-3-methylphenyl]pentan-3-yl]-N-[(2S)-1-hydroxypropan-2-yl]pyrrole-2-carboxamide
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|
C28H44N2O4
|
1
|
1 |
IC50 = 15780 nM
|
|
|
CP0018072
|
US10662186, Compound 63
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|
C27H32F2N8
|
1
|
1 |
IC50 = 36.2 nM
|
|
|
CP0086325
|
2-amino-5-(3,4-dimethylphenyl)-5,5-diphenylpentanoic acid
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|
C25H27NO2
|
1
|
1 |
GI50 = 44 nM
|
|
|
CP0086818
|
ethyl 7-[3-[[3-(trifluoromethyl)benzoyl]amino]phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxylate
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|
C23H17F3N4O3
|
1
|
1 |
IC50 = 3250 nM
|
|
|
CP0112599
|
US8569511, 2
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|
C23H22F2N6O2
|
1
|
1 |
IC50 = 430 nM
|
|
|
CP0117454
|
2-(5-chloro-2-(2-methoxy-4-morpholinophenylamino)pyrimidin-4-ylamino)-N-methylbenzamide
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|
C23H25ClN6O3
|
2
|
1 |
IC50 = 1030 nM
|
|
|
2 |
IC50 > 10000 nM
|
|
|
CP0156010
|
(2R)-2-amino-3-[(3-ethyl-4-methylphenyl)-diphenylmethyl]sulfanylpropanoic acid
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|
C25H27NO2S
|
1
|
1 |
GI50 = 26 nM
|
|
|
CP0158116
|
4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]phenyl}-amino)-7-[(1E)-4-(4-ethylpiperazin-1-yl)but-1-enyl]quinoline-3-carbonitrile
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|
C30H32ClN7S
|
1
|
1 |
IC50 = 48 nM
|
|
|
CP0250629
|
(2R)-2-amino-3-[(3,4-dimethylphenyl)-diphenylmethyl]sulfanylpropanoic acid
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|
C24H25NO2S
|
1
|
1 |
GI50 = 124 nM
|
|
|
CP0329823
|
2-Acetylfuranonaphthoquinone
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|
C14H8O4
|
2
|
1 |
IC50 = 1300 nM
|
|
|
2 |
IC50 = 1400 nM
|
|
|
CP0397754
|
2-[[5-chloro-2-[4-(1-morpholin-4-yl-1-oxobutan-2-yl)oxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C26H29ClN6O4
|
1
|
1 |
IC50 = 8730 nM
|
|
|
CP0411565
|
2-(4-indol-1-ylbutyl)-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline
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|
C23H28N2O2
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0417440
|
N-(4-ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-yl)-1,3-thiazol-2-amine
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|
C19H18N4OS
|
1
|
1 |
GI50 = 3 nM
|
|
|
CP0431822
|
3-[(Z)-[1-[4-(4-cyclohexylpiperazin-1-yl)butyl]-2H-indol-3-ylidene]amino]-1,1-dimethylthiourea
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|
C25H40N6S
|
1
|
1 |
EC50 = 6150 nM
|
|
|
CP0452777
|
1-[3-[4-[1-adamantyl(phenyl)methyl]phenyl]propyl]-4-methylpiperazine
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|
C31H42N2
|
1
|
1 |
GI50 = 3.41 nM
|
|
|
CP0472068
|
3-[(Z)-[1-[4-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)butyl]-2H-indol-3-ylidene]amino]-1,1-dimethylthiourea
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|
C26H35N5O2S
|
1
|
1 |
EC50 = 2340 nM
|
|
|
CP0517268
|
1-[4-[1-adamantyl(phenyl)methyl]phenyl]-4-ethylpiperazine
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|
C29H38N2
|
1
|
1 |
LC50 > 100000 nM
|
|
|
CP0519012
|
2-[[5-chloro-2-[4-(1-morpholin-4-yl-1-oxopropan-2-yl)oxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C25H27ClN6O4
|
1
|
1 |
IC50 = 5340 nM
|
|
|
CP0524983
|
1-[4-[1-adamantyl(phenyl)methyl]phenyl]-4-benzylpiperazine
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|
C34H40N2
|
1
|
1 |
GI50 = 7510 nM
|
|
|
CP0529687
|
2-[[5-chloro-2-[4-(2-morpholin-4-yl-2-oxoethoxy)anilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C24H25ClN6O4
|
1
|
1 |
IC50 = 5990 nM
|
|
|
CP0535102
|
N-[2-[4-[5-[[2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]pentyl]piperidin-1-yl]ethyl]-4,9-dioxobenzo[f][1]benzofuran-2-carboxamide
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|
C39H41N5O8
|
1
|
1 |
IC50 = 3400 nM
|
|
|
CP0536607
|
2-[[2-[4-[[ethoxy(morpholin-4-yl)phosphoryl]methyl]anilino]-5-nitropyrimidin-4-yl]amino]-N-methylbenzamide
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|
C25H30N7O6P
|
1
|
1 |
IC50 = 1020 nM
|
|
|
CP0546239
|
N-[2-[4-[5-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]pentyl]piperidin-1-yl]ethyl]-4,9-dioxobenzo[f][1]benzofuran-2-carboxamide
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|
C38H39N5O8
|
1
|
1 |
IC50 = 2100 nM
|
|
|
CP0561801
|
N-[2-[2-[2-[2-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-4,9-dioxobenzo[f][1]benzofuran-2-carboxamide
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|
C36H36N4O12
|
1
|
1 |
IC50 = 10100 nM
|
|
|
CP0561956
|
2-[[5-chloro-2-[4-[(4-methoxyphenyl)sulfonylamino]-3-methylanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C26H25ClN6O4S
|
1
|
1 |
IC50 = 10600 nM
|
|
|
CP0564443
|
2-[[5-chloro-2-[4-[(4-fluorophenyl)sulfonylamino]-3-methoxyanilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C25H22ClFN6O4S
|
1
|
1 |
IC50 = 31600 nM
|
|
|
CP0565884
|
(2S,4R)-1-[(2S)-2-[[2-[2-[(4,9-dioxobenzo[f][1]benzofuran-2-carbonyl)amino]ethoxy]acetyl]amino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
Show/Hide
|
C39H41N5O9S
|
1
|
1 |
IC50 > 30000 nM
|
|
|
CP0568939
|
2-[[5-chloro-2-[4-[(4-methoxyphenyl)sulfonylamino]anilino]pyrimidin-4-yl]amino]-N-methylbenzamide
Show/Hide
|
C25H23ClN6O4S
|
1
|
1 |
IC50 = 24100 nM
|
|
|
CP0575085
|
2-[[5-chloro-2-[4-(2-morpholin-4-yl-2-oxoethoxy)anilino]pyrimidin-4-yl]amino]-N-cyclopropylbenzamide
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|
C26H27ClN6O4
|
1
|
1 |
IC50 > 10000 nM
|
|
|
CP0575678
|
2-[[5-chloro-2-[4-[(4-methylphenyl)sulfonylamino]anilino]pyrimidin-4-yl]amino]-N-methylbenzamide
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|
C25H23ClN6O3S
|
1
|
1 |
IC50 = 19400 nM
|
|
|
CP0955356
|
N'-[(1S)-2-[[(1S)-5-amino-1-[[(1S)-1-[(2S)-2-[[(1S)-1-[[(1S)-1-carbamoyl-3-methylsulfanyl-propyl]carbamoyl]-2-methyl-propyl]carbamoyl]pyrrolidine-1-carbonyl]-3-methyl-butyl]carbamoyl]pentyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]-N-[1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-oxo-pyrimidin-4-yl]butanediamide
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|
C51H74F2N12O12S
|
1
|
1 |
IC50 = 180 nM
|
|
|
CP0963259
|
(2S)-N-[(1S)-1-[[(1S)-1-[[(1S)-2-amino-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]carbamoyl]-3-methylsulfanyl-propyl]carbamoyl]-2-methyl-propyl]-1-[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-4-methyl-pentanoyl]pyrrolidine-2-carboxamide
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|
C38H61N9O6S
|
1
|
1 |
IC50 > 1000 nM
|
|
|
CP0968860
|
N'-[(1S)-2-[[(1S)-1-[(2S)-2-[[(1S,2R)-1-[[(1S)-1-[[(1S)-5-amino-1-carbamoyl-pentyl]carbamoyl]-3-methyl-butyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]pyrrolidine-1-carbonyl]-2-methyl-propyl]amino]-1-(1H-indol-3-ylmethyl)-2-oxo-ethyl]-N-[1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-2-oxo-pyrimidin-4-yl]butanediamide
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|
C50H72F2N12O13
|
1
|
1 |
IC50 = 200 nM
|
|
|