General Information of the Cell Line
Cell Line ID
CL000217
Cell Line Name
CAL-27
Synonyms
Cal-27
CAL 27
Cal 27
CAL27
Cal27
Centre Antoine Lacassagne-27
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1107
Tissue Information
Tongue
Disease
Tongue adenosquamous carcinoma (NCIt: C173807)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00922, Epidermal growth factor receptor
 Protein Info 
Compound ID Compound Name Compound Formula
CP0007142
 Compound Info 
N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
   Show/Hide
C29H26ClFN4O4S
  1
1
IC50 < 32 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0118527
 Compound Info 
3-{5-[4-(3-Chloro-4-(3-fluorobenzyloxy)phenylamino]quinazolin-6-yl}furan-2-yl)-N-hydroxy-acrylamideHydrochlorideMonohydrate
   Show/Hide
C28H20ClFN4O4
  1
1
IC50 < 32 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0232444
 Compound Info 
(E)-3-{3-[4-(3-Chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)phenyl)-N-hydroxyacrylamide
   Show/Hide
C30H22ClFN4O3
  1
1
IC50 = 500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0002778
 Compound Info 
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
   Show/Hide
 C29H31N7O  1
1
IC50 = 19952.62 nM
   TI
   LI
   LO
   TS
CP0003832
 Compound Info 
N'-hydroxy-N-phenyloctanediamide
   Show/Hide
 C14H20N2O3  1
1
IC50 = 2640 nM
   TI
   LI
   LO
   TS
CP0004545
 Compound Info 
N-[2-(benzylamino)-2-oxoethyl]-N-[6-(hydroxyamino)-6-oxohexyl]-3,5-dimethylbenzamide
   Show/Hide
 C24H31N3O4  1
1
IC50 = 700 nM
   TI
   LI
   LO
   TS
CP0007142
 Compound Info 
N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
   Show/Hide
 C29H26ClFN4O4S  1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
CP0008774
 Compound Info 
N-[6-(2-aminoanilino)-6-oxohexyl]-N-[2-(benzylamino)-2-oxoethyl]naphthalene-1-carboxamide
   Show/Hide
 C32H34N4O3  1
1
IC50 = 11000 nM
   TI
   LI
   LO
   TS
CP0008775
 Compound Info 
N-[6-(2-aminoanilino)-6-oxohexyl]-N-[2-[(3,5-dimethylphenyl)methylamino]-2-oxoethyl]-3,5-dimethylbenzamide
   Show/Hide
 C32H40N4O3  1
1
IC50 = 19300 nM
   TI
   LI
   LO
   TS
CP0010069
 Compound Info 
4-(dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-N-[2-(4-methylanilino)-2-oxoethyl]benzamide
   Show/Hide
 C24H32N4O4  1
1
IC50 = 530 nM
   TI
   LI
   LO
   TS
CP0011812
 Compound Info 
N-[[4-[(2-amino-5-phenylphenyl)carbamoyl]phenyl]methyl]-N-[2-(benzylamino)-2-oxoethyl]-3,5-dimethylbenzamide
   Show/Hide
 C38H36N4O3  1
1
IC50 = 8900 nM
   TI
   LI
   LO
   TS
CP0012954
 Compound Info 
N-[6-(2-aminoanilino)-6-oxohexyl]-N-[2-(benzylamino)-2-oxoethyl]-4-(dimethylamino)benzamide
   Show/Hide
 C30H37N5O3  1
1
IC50 = 16000 nM
   TI
   LI
   LO
   TS
CP0013604
 Compound Info 
N-[6-(2-amino-5-fluoroanilino)-6-oxohexyl]-N-[2-(benzylamino)-2-oxoethyl]-4-(dimethylamino)benzamide
   Show/Hide
 C30H36FN5O3  1
1
IC50 = 20200 nM
   TI
   LI
   LO
   TS
CP0015318
 Compound Info 
N-[6-(2-aminoanilino)-6-oxohexyl]-N-[2-(benzylamino)-2-oxoethyl]-3,5-dimethylbenzamide
   Show/Hide
 C30H36N4O3  1
1
IC50 = 13700 nM
   TI
   LI
   LO
   TS
CP0015319
 Compound Info 
N-[6-(2-amino-5-phenylanilino)-6-oxohexyl]-N-[2-(benzylamino)-2-oxoethyl]-3,5-dimethylbenzamide
   Show/Hide
 C36H40N4O3  1
1
IC50 = 18900 nM
   TI
   LI
   LO
   TS
CP0053560
 Compound Info 
(E)-N-(2-aminophenyl)-3-(3-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)phenyl)acrylamide
   Show/Hide
 C36H27ClFN5O2  1
1
IC50 > 16000 nM
   TI
   LI
   LO
   TS
CP0077992
 Compound Info 
[4-(3-chloro-4-fluoroanilino)thieno[2,3-d]pyrimidin-6-yl]-(5-hydroxy-1H-indol-2-yl)methanone
   Show/Hide
 C21H12ClFN4O2S  1
1
IC50 = 1280 nM
   TI
   LI
   LO
   TS
CP0095287
 Compound Info 
[4-(3-chloroanilino)thieno[2,3-d]pyrimidin-6-yl]-(1H-indol-2-yl)methanone
   Show/Hide
 C21H13ClN4OS  1
1
IC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0118530
 Compound Info 
5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)-N-hydroxythiophene-2-carboxamide
   Show/Hide
 C26H18ClFN4O3S  1
1
IC50 = 650 nM
   TI
   LI
   LO
   TS
CP0118633
 Compound Info 
N-(2-aminophenyl)-5-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]thiophene-2-carboxamide
   Show/Hide
 C32H23ClFN5O2S  1
1
IC50 = 710 nM
   TI
   LI
   LO
   TS
CP0118656
 Compound Info 
(E)-3-(4-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)phenyl)-N-hydroxyacrylamide
   Show/Hide
 C30H22ClFN4O3  1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
CP0118658
 Compound Info 
5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)-N-hydroxyfuran-2-carboxamide
   Show/Hide
 C26H18ClFN4O4  1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
CP0151685
 Compound Info 
N-(2-aminophenyl)-4-[[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]anilino]methyl]benzamide
   Show/Hide
 C30H27N7O  1
1
IC50 = 6309.57 nM
   TI
   LI
   LO
   TS
CP0166969
 Compound Info 
N-(2-aminophenyl)-5-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]furan-2-carboxamide
   Show/Hide
 C32H23ClFN5O3  1
1
IC50 = 330 nM
   TI
   LI
   LO
   TS
CP0173297
 Compound Info 
3-[3-(benzofuran-2-carbonyl)phenyl]-N-hydroxyacrylamide
   Show/Hide
 C18H13NO4  1
1
IC50 = 660 nM
   TI
   LI
   LO
   TS
CP0204863
 Compound Info 
(E)-N-hydroxy-3-(4-((4-methyl-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)phenylamino)methyl)phenyl)acrylamide
   Show/Hide
 C26H24N6O2  2
1
IC50 = 5010 nM
   TI
   LI
   LO
   TS
2
IC50 = 5011.87 nM
   TI
   LI
   LO
   TS
CP0232442
 Compound Info 
(E)-3-(5-(4-(3-chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)thiophen-2-yl)-N-hydroxyacrylamide
   Show/Hide
 C28H20ClFN4O3S  1
1
IC50 = 660 nM
   TI
   LI
   LO
   TS
CP0232444
 Compound Info 
(E)-3-{3-[4-(3-Chloro-4-(3-fluorobenzyloxy)phenylamino)quinazolin-6-yl)phenyl)-N-hydroxyacrylamide
   Show/Hide
 C30H22ClFN4O3  1
1
IC50 = 590 nM
   TI
   LI
   LO
   TS
CP0283354
 Compound Info 
N-(2-aminophenyl)-3-[4-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]quinazolin-6-yl]phenyl]propanamide
   Show/Hide
 C36H29ClFN5O2  1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Tongue)
Cell Line Name Organism Disease
HN-5
 Cell Line Info 
Homo sapiens (Human) Tongue squamous cell carcinoma
CAL-33
 Cell Line Info 
Homo sapiens (Human) Tongue squamous cell carcinoma
H103
 Cell Line Info 
Homo sapiens (Human) Tongue squamous cell carcinoma