Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-{5-[4-(3-Chloro-4-(3-fluorobenzyloxy)phenylamino]quinazolin-6-yl}furan-2-yl)-N-hydroxy-acrylamideHydrochlorideMonohydrate
    Show/Hide
 PubChem ID
CID: 49855568
SID: 104228571
Canonical SMILES
ONC(=O)\C=C\c1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1
    Show/Hide
Compound Formula C28H20ClFN4O4
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000217 CAL-27
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 < 32 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.5 nM