| Compound ID |
Compound Name |
Compound Formula |
|
CP0256326
|
CHEMBL3770588
Show/Hide
|
C28H31ClN6O
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0156094
|
6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-8-[[(4S)-3,3-difluoropiperidin-4-yl]methyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C26H25ClF2N6O
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0486462
|
CHEMBL3769478
Show/Hide
|
C26H27ClN6O3
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0070883
|
8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C25H25ClN6O3
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0090236
|
6-[2-chloro-4-(6-methylpyridin-2-yl)phenyl]-8-(5,9-dioxa-2-azaspiro[3.5]nonan-7-ylmethyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C27H27ClN6O3
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0072137
|
2-N-[(4-chloro-1H-benzimidazol-5-yl)methyl]-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-N-ethylpyrimidine-2,4-diamine
Show/Hide
|
C20H21ClN8
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0677749
|
N2-((4-Chloro-1H-benzo[d]imidazol-5-yl)methyl)-N4-(5-cyclopropyl-1H-pyrazol-3-yl)-N2-methylpyrimidine-2,4-diamine
Show/Hide
|
C19H19ClN8
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0698981
|
(S)-N2-(1-(1H-Indol-5-yl)ethyl)-N4-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Show/Hide
|
C20H21N7
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0231643
|
8-[(4-aminocyclohexyl)methyl]-6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C27H30ClN7O
|
1
|
| 1 |
IC50 = 124 nM
|
|
|
|
CP0231644
|
6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)-8-(piperidin-4-ylmethyl)pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C26H28ClN7O
|
1
|
| 1 |
IC50 = 145 nM
|
|
|
|
CP0256327
|
8-(4-aminobutyl)-6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C24H26ClN7O
|
1
|
| 1 |
IC50 = 147 nM
|
|
|
|
CP0452337
|
8-[(5-amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C25H26ClN7O3
|
1
|
| 1 |
IC50 = 148 nM
|
|
|
|
CP0098902
|
6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-[2-(1-methylpiperidin-4-yl)ethylamino]pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C28H32ClN7O
|
1
|
| 1 |
IC50 = 222 nM
|
|
|
|
CP0709895
|
N2-[(1S)-1-(1H-Benzimidazol-5-yl)ethyl]-N4-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Show/Hide
|
C19H20N8
|
1
|
| 1 |
IC50 = 281 nM
|
|
|
|
CP0256325
|
8-[(4-aminocyclohexyl)methyl]-6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C26H28ClN7O
|
1
|
| 1 |
IC50 = 341 nM
|
|
|
|
CP0252383
|
2-N-[(4-chloro-1H-benzimidazol-5-yl)methyl]-4-N-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Show/Hide
|
C18H17ClN8
|
1
|
| 1 |
IC50 = 362 nM
|
|
|
|
CP0111952
|
6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(methylamino)-8-[[(2R)-morpholin-2-yl]methyl]pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C24H24ClN7O2
|
1
|
| 1 |
IC50 = 399 nM
|
|
|
|
CP0472537
|
6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)-8-[(2-oxopiperidin-4-yl)methyl]pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C26H26ClN7O2
|
1
|
| 1 |
IC50 = 813 nM
|
|
|
|
CP0256324
|
6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(ethylamino)-8-(3-hydroxypropyl)pyrido[2,3-d]pyrimidin-7-one
Show/Hide
|
C23H23ClN6O2
|
1
|
| 1 |
IC50 = 980 nM
|
|
|
|
CP0733200
|
N2-((trans-4-Aminocyclohexyl)methyl)-N4-(5-cyclopropyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine
Show/Hide
|
C17H25N7
|
1
|
| 1 |
IC50 = 2200 nM
|
|
|
