Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-8-ethyl-2-[2-(1-methylpiperidin-4-yl)ethylamino]pyrido[2,3-d]pyrimidin-7-one
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 PubChem ID
CID: 71557891
SID: 163557958
Canonical SMILES
CCn1c2nc(NCCC3CCN(C)CC3)ncc2cc(-c2ccc(cc2Cl)-c2cncc(C)n2)c1=O
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Compound Formula C28H32ClN7O
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase PAK 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE20 family
>
STE protein kinase PAKA subfamily
Uniprot ID
Q13153
Gene Name
PAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000504 EBC-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 222 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 0.023 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 <= 10 nM
2 Ki = 22 nM