Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-[2-chloro-4-(6-methylpyrazin-2-yl)phenyl]-2-(methylamino)-8-[[(2R)-morpholin-2-yl]methyl]pyrido[2,3-d]pyrimidin-7-one
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 PubChem ID
CID: 90467771
Canonical SMILES
CNc1ncc2cc(-c3ccc(cc3Cl)-c3cncc(C)n3)c(=O)n(C[C@H]3CNCCO3)c2n1
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Compound Formula C24H24ClN7O2
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase PAK 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
STE protein kinase group
>
STE protein kinase STE20 family
>
STE protein kinase PAKA subfamily
Uniprot ID
Q13153
Gene Name
PAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000504 EBC-1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 399 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 19 nM