Brief Information of the Cell Line and Protein
Cell Line ID: CL000389 , CHO-DXB11
Synonyms
CHO DXB11
DXB11-CHO
CHO-DUX-B11
CHO (Dux B11)
CHO-DUK-XB11
DUK-XB11
CHO-DUKX B11
CHO-DUKXB11
DUKX-B11
DUX B11
DUXB11
DXB-11
DXB11
CHO-DUKX
DUKX-CHO
DUKX
CHO-DHFR -
CHO/dhFr-
CHO/dhfr-
CHO(dhfr-)
CHO duk-
CHOd-
CHO B11
B11
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_1977
Protein ID: PT00943 , D(3) dopamine receptor
Gene Name DRD3
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P35462
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000389  Protein ID: PT00943
 
Compound ID Compound Name Compound Formula
CP0048038
2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-1-one
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C25H33N3O2
 1
1
EC50 = 0.33 nM
   TI
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CP0006107
CAS_85760-74-3
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C13H21N3
 4
1
EC50 = 1.4 nM
   TI
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2
EC50 = 2.1 nM
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3
EC50 = 2.6 nM
   TI
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4
EC50 = 2.9 nM
   TI
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CP0266686
N-[4-[(4-ethynylcyclohex-3-en-1-yl)-propylamino]butyl]-4-phenylbenzamide
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C28H34N2O
 2
1
EC50 = 1.6 nM
   TI
   LI
   LO
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2
EC50 = 2.1 nM
   TI
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CP0071762
N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]naphthalene-2-carboxamide
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C26H31N3O2
 1
1
EC50 = 1.8 nM
   TI
   LI
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CP0142591
3,4-Dihydro-6-(2-furyl)-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]isoquinolin-1(2H)-one
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C28H33N3O3
 1
1
EC50 = 2.3 nM
   TI
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CP0389512
4-ethynyl-N-[4-[4-(4-phenylphenyl)triazol-1-yl]butyl]-N-propylcyclohex-3-en-1-amine
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C29H34N4
 2
1
EC50 = 2.6 nM
   TI
   LI
   LO
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2
EC50 = 3.1 nM
   TI
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CP0332114
3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]-6-(2-thienyl)isoquinolin-1(2H)-one
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C28H33N3O2S
 1
1
EC50 = 2.8 nM
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CP0142590
2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-3,4-dihydroisoquinolin-1(2H)-one
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C24H31N3O2
 1
1
EC50 = 3.3 nM
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CP0291460
3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]-6-phenylisoquinolin-1(2H)-one
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C30H35N3O2
 1
1
EC50 = 3.3 nM
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CP0374901
3-(4-Fluoro-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide
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C24H30FN3O2
 1
1
EC50 = 3.9 nM
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CP0129799
(4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine
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C14H23N
 2
1
EC50 = 4.4 nM
   TI
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2
EC50 = 7.7 nM
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CP0446059
N-[4-[4-(3-chloro-2-methoxyphenyl)piperazin-1-yl]butyl]tricyclo[8.2.2.24,7]hexadeca-1(13),4,6,10(14),11,15-hexaene-5-carboxamide
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C32H38ClN3O2
 1
1
EC50 = 18 nM
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CP0433429
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]tricyclo[8.2.2.24,7]hexadeca-1(13),4,6,10(14),11,15-hexaene-5-carboxamide
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C31H35Cl2N3O
 1
1
EC50 = 110 nM
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