Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4-Ethynyl-cyclohex-3-enyl)-dipropyl-amine
    Show/Hide
 PubChem ID
CID: 4420454
SID: 15266373
Canonical SMILES
CCCN(CCC)C1CCC(=CC1)C#C
    Show/Hide
Compound Formula C14H23N
Compound Structure
Protein Name
 Protein Info 
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000389 CHO-DXB11
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 4.4 nM
   TI
   LI
   LO
   TS
2
EC50 = 7.7 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  3
1
Ki = 190 nM
   TI
   LI
   LO
   TS
2
Ki = 5700 nM
   TI
   LI
   LO
   TS
3
Ki > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 5.2 nM
2 Ki = 23 nM
3 Ki = 350 nM
4 Ki = 590 nM
5 Ki = 720 nM