Brief Information of the Compound and Protein
Compound Name
2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-1-one
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PubChem ID
CID: 25256816
SID: 58090926
Canonical SMILES
COc1ccccc1N1CCN(CCCCN2CCCc3ccccc3C2=O)CC1
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Compound Formula C25H33N3O2
Compound Structure
Protein Name
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 0.27 nM
   TI
   LI
   LO
   TS
CL000389 CHO-DXB11 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 0.33 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.585 nM