Brief Information of the Cell Line and Protein
Cell Line ID: CL000108 , CCRF-CEM
 Cell Line Info 
Synonyms
CCRF/CEM
CCRFCEM
CCRF.CEM
CCRF CEM
CCRF
CEM
CEM-CCRF
CEM-CCRF (CAMR)
CCRF/CEM/0
CEM/0
CEM-0
CCRF-CEM/S
GM03671
GM03671C
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0207
Protein ID: PT01651 , Dihydrofolate reductase
 Protein Info 
Gene Name DHFR
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P00374
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000108
 Cell Line Info 
 Protein ID: PT01651
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0148537
 Compound Info 
2-[[4-carboxy-4-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]butyl]carbamoyl]benzoic acid
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C27H27N9O6
  1
1
IC50 = 1.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0238793
 Compound Info 
(S)-2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-propyl]-benzoylamino}-pentanedioic acid
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C22H25N7O5
  1
1
IC50 = 2.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0053031
 Compound Info 
4-Aminofolic acid
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C19H20N8O5
  1
1
IC50 = 3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0069691
 Compound Info 
CHEBI:15640
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C20H23N7O7
  1
1
Ki = 2370 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS