Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-2-{4-[1-(2,4-Diamino-pteridin-6-ylmethyl)-propyl]-benzoylamino}-pentanedioic acid
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 PubChem ID
CID: 6917908
SID: 14882817
Canonical SMILES
CCC(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
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Compound Formula C22H25N7O5
Compound Structure
Protein Name
 Protein Info 
Dihydrofolate reductase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P00374
Gene Name
DHFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000108 CCRF-CEM
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 2.6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4.4 nM