Brief Information of the Cell Line and Protein
Cell Line ID: CL000083 , MCF-7
 Cell Line Info 
Synonyms
MCF 7
MCF.7
MCF7
Michigan Cancer Foundation-7
ssMCF-7
ssMCF7
MCF7/WT
MCF7-CTRL
IBMF-7
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0031
Protein ID: PT01104 , Insulin-like growth factor 1 receptor
 Protein Info 
Gene Name IGF1R
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P08069
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000083
 Cell Line Info 
 Protein ID: PT01104
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0153830
 Compound Info 
N-[4-[[5,5-dimethyl-2,4-dioxo-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidin-1-yl]methyl]pyridin-2-yl]acetamide
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C20H19F3N4O3S
  1
1
IC50 = 7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0422831
 Compound Info 
1-((2-aminopyridin-4-yl)methyl)-5,5-dimethyl-3-(4-(trifluoromethylthio)phenyl)imidazolidine-2,4-dione
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C18H17F3N4O2S
  1
1
IC50 = 34 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0091819
 Compound Info 
5,5-dimethyl-1-((2-(methylamino)pyridin-4-yl)methyl)-3-(4-(trifluoromethylthio)phenyl)imidazolidine-2,4-dione
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C19H19F3N4O2S
  1
1
IC50 = 43 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0460290
 Compound Info 
1-((2-(ethylamino)pyridin-4-yl)methyl)-5,5-dimethyl-3-(4-(trifluoromethylthio)phenyl)imidazolidine-2,4-dione
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C20H21F3N4O2S
  1
1
IC50 = 47 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0512753
 Compound Info 
5,5-dimethyl-1-(pyridin-4-ylmethyl)-3-(4-(trifluoromethylthio)phenyl)imidazolidine-2,4-dione
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C18H16F3N3O2S
  1
1
IC50 = 117 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0422860
 Compound Info 
2-(5,6-dimethoxy-1-methyl-1H-indol-3-yl)-1H-pyrrolo[2,3-b]pyridine
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C18H17N3O2
  2
1
IC50 = 145 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 180 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0655488
 Compound Info 
(S)-5-methyl-1-(quinolin-4-ylmethyl)-3-(4-(trifluoromethylsulfonyl)phenyl)imidazolidine-2,4-dione
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C21H16F3N3O4S
  1
1
IC50 = 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS