Brief Information of the Compound and Protein
Compound Name
5,5-dimethyl-1-(pyridin-4-ylmethyl)-3-(4-(trifluoromethylthio)phenyl)imidazolidine-2,4-dione
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PubChem ID
CID: 54586287
Canonical SMILES
CC1(C)N(Cc2ccncc2)C(=O)N(C1=O)c1ccc(SC(F)(F)F)cc1
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Compound Formula C18H16F3N3O2S
Compound Structure
Protein Name
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7 Homo sapiens (Human)  1
1
IC50 = 117 nM
   TI
   LI
   LO
   TS
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 264 nM
   TI
   LI
   LO
   TS