General Information of the Compound
| Compound ID |
CP0153830
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| Compound Name |
N-[4-[[5,5-dimethyl-2,4-dioxo-3-[4-(trifluoromethylsulfanyl)phenyl]imidazolidin-1-yl]methyl]pyridin-2-yl]acetamide
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| Structure |
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| Formula |
C20H19F3N4O3S
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| Molecular Weight |
452.458
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| Canonical SMILES |
CC(=O)Nc1cc(CN2C(=O)N(C(=O)C2(C)C)c2ccc(SC(F)(F)F)cc2)ccn1
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| InChI |
InChI=1S/C20H19F3N4O3S/c1-12(28)25-16-10-13(8-9-24-16)11-26-18(30)27(17(29)19(26,2)3)14-4-6-15(7-5-14)31-20(21,22)23/h4-10H,11H2,1-3H3,(H,24,25,28)
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| InChIKey |
JXIZWVBNXZXRKO-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01104, Insulin-like growth factor 1 receptor
Cell-based Assay