Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-(5,6-dimethoxy-1-methyl-1H-indol-3-yl)-1H-pyrrolo[2,3-b]pyridine
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 PubChem ID
CID: 22477349
Canonical SMILES
COc1cc2c(cn(C)c2cc1OC)-c1cc2cccnc2[nH]1
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Compound Formula C18H17N3O2
Compound Structure
Protein Name
 Protein Info 
Insulin-like growth factor 1 receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase InsR family
Uniprot ID
P08069
Gene Name
IGF1R
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 145 nM
   TI
   LI
   LO
   TS
2
IC50 = 180 nM
   TI
   LI
   LO
   TS
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  4
1
IC50 = 33 nM
   TI
   LI
   LO
   TS
2
IC50 = 34 nM
   TI
   LI
   LO
   TS
3
IC50 = 35 nM
   TI
   LI
   LO
   TS
4
IC50 = 55 nM
   TI
   LI
   LO
   TS