| Compound ID |
Compound Name |
Compound Formula |
|
CP0572894
|
N,3-dimethyl-5-[6-[(3S)-oxolan-3-yl]oxy-7-(1-propan-2-ylpyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]benzamide
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|
C25H28N6O3
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
|
|
CP0952841
|
(S)-5-(6-(1-Isopropyl-1H-pyrazol-4-yl)-5-((tetrahydrofuran-3-yl)oxy)pyrazolo[1,5-a]pyrimidin-3-yl)-N-(methyl-d3)nicotinamide
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|
C23H25N7O3
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0573520
|
US11566028, Example 63
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|
C23H25N7O3
|
1
|
| 1 |
IC50 = 7.2 nM
|
|
|
|
CP0543600
|
4-fluoro-N,3-dimethyl-5-[7-(1-methylpyrazol-4-yl)-6-[(3S)-oxolan-3-yl]oxyimidazo[1,2-b]pyridazin-3-yl]benzamide
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|
C23H23FN6O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0546171
|
3-(difluoromethyl)-4-fluoro-N-methyl-5-[7-(1-methylpyrazol-4-yl)-6-[(3S)-oxolan-3-yl]oxyimidazo[1,2-b]pyridazin-3-yl]benzamide
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|
C23H21F3N6O3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0546221
|
4-fluoro-3-[6-methoxy-7-(1-methylpyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]-N-methylbenzamide
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|
C19H17FN6O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0576753
|
N-methyl-3-[7-(1-methylpyrazol-4-yl)-6-[(3S)-oxolan-3-yl]oxyimidazo[1,2-b]pyridazin-3-yl]benzamide
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|
C22H22N6O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0575470
|
N-ethyl-5-[6-(1-ethylpyrazol-4-yl)-5-[(3S)-oxolan-3-yl]oxypyrazolo[1,5-a]pyrimidin-3-yl]pyridine-3-carboxamide
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|
C23H25N7O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0551969
|
US11566028, Example 3
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|
C21H21N7O3
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0575345
|
N-methyl-3-[7-(1-methylpyrazol-4-yl)-6-(oxetan-3-yloxy)imidazo[1,2-b]pyridazin-3-yl]benzamide
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|
C21H20N6O3
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0572978
|
3-[6-methoxy-7-(1-methylpyrazol-4-yl)imidazo[1,2-b]pyridazin-3-yl]-N-methylbenzamide
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|
C19H18N6O2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0550308
|
N-methyl-3-[7-(1-methylpyrazol-4-yl)-6-(oxolan-3-yloxy)imidazo[1,2-b]pyridazin-3-yl]benzamide
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|
C22H22N6O3
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0577915
|
3,4-difluoro-N-methyl-5-[7-(1-methylpyrazol-4-yl)-6-[(3S)-oxolan-3-yl]oxyimidazo[1,2-b]pyridazin-3-yl]benzamide
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|
C22H20F2N6O3
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0575346
|
N-methyl-5-[7-(1-methylpyrazol-4-yl)-6-(oxolan-3-yloxy)imidazo[1,2-b]pyridazin-3-yl]pyridine-3-carboxamide
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|
C21H21N7O3
|
1
|
| 1 |
IC50 = 969 nM
|
|
|
|
CP0155468
|
1-[3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]-3-[3-(trifluoromethyl)phenyl]urea
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|
C27H20F3N5O2
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0378059
|
N-[3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]-3-(trifluoromethyl)benzamide
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|
C27H19F3N4O2
|
1
|
| 1 |
IC50 = 6300 nM
|
|
|
|
CP0111985
|
3-(4-methylimidazol-1-yl)-N-[3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]-5-(trifluoromethyl)benzamide
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|
C31H23F3N6O2
|
1
|
| 1 |
IC50 = 7700 nM
|
|
|
|
CP0333107
|
1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-methyl-3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]urea
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|
C28H21F4N5O2
|
1
|
| 1 |
IC50 = 9300 nM
|
|
|
|
CP0346926
|
5-[(Z)-[6-[3-[[3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)benzoyl]amino]anilino]-2-oxo-1H-indol-3-ylidene]methyl]-1H-pyrrole-3-carboxylic acid
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|
C33H29F3N6O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
