General Information of the Compound
| Compound ID |
CP0575470
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| Compound Name |
N-ethyl-5-[6-(1-ethylpyrazol-4-yl)-5-[(3S)-oxolan-3-yl]oxypyrazolo[1,5-a]pyrimidin-3-yl]pyridine-3-carboxamide
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| Structure |
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| Formula |
C23H25N7O3
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| Molecular Weight |
447.499
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| Canonical SMILES |
CCNC(=O)c1cncc(c1)-c1cnn2cc(-c3cnn(CC)c3)c(O[C@H]3CCOC3)nc12
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| InChI |
InChI=1S/C23H25N7O3/c1-3-25-22(31)16-7-15(8-24-9-16)19-11-27-30-13-20(17-10-26-29(4-2)12-17)23(28-21(19)30)33-18-5-6-32-14-18/h7-13,18H,3-6,14H2,1-2H3,(H,25,31)/t18-/m0/s1
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| InChIKey |
CCVQDAVSKDENJO-SFHVURJKSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT06924, Fibroblast growth factor receptor 3