General Information of the Compound
| Compound ID |
CP0543600
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| Compound Name |
4-fluoro-N,3-dimethyl-5-[7-(1-methylpyrazol-4-yl)-6-[(3S)-oxolan-3-yl]oxyimidazo[1,2-b]pyridazin-3-yl]benzamide
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| Formula |
C23H23FN6O3
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| Molecular Weight |
450.474
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| Canonical SMILES |
CNC(=O)c1cc(C)c(F)c(c1)-c1cnc2cc(-c3cnn(C)c3)c(O[C@H]3CCOC3)nn12
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| InChI |
InChI=1S/C23H23FN6O3/c1-13-6-14(22(31)25-2)7-18(21(13)24)19-10-26-20-8-17(15-9-27-29(3)11-15)23(28-30(19)20)33-16-4-5-32-12-16/h6-11,16H,4-5,12H2,1-3H3,(H,25,31)/t16-/m0/s1
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| InChIKey |
GUXJNJORIXUBRE-INIZCTEOSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01411, Fibroblast growth factor receptor 3
Protein ID: PT06924, Fibroblast growth factor receptor 3