| Compound ID |
Compound Name |
Compound Formula |
|
CP0441015
|
N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]propanamide
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|
C30H31F3N6OS
|
2
|
| 1 |
GI50 < 1 nM
|
|
|
| 2 |
GI50 = 3 nM
|
|
|
|
CP0470563
|
3-(2-imidazo[1,5-b]pyridazin-7-ylethynyl)-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
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|
C29H27F3N6O
|
2
|
| 1 |
GI50 < 1 nM
|
|
|
| 2 |
GI50 = 2 nM
|
|
|
|
CP0387299
|
4-(methylamino)-2-[4-methyl-3-(propanoylamino)anilino]-N-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]phenyl]pyrimidine-5-carboxamide
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|
C31H30F3N7O3
|
1
|
| 1 |
GI50 = 44 nM
|
|
|
|
CP0010193
|
AG-013736
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|
C22H18N4OS
|
2
|
| 1 |
GI50 = 110 nM
|
|
|
| 2 |
GI50 = 120 nM
|
|
|
|
CP0389976
|
4-(methylamino)-2-[4-methyl-3-(prop-2-enoylamino)anilino]-N-[2-methyl-5-[[3-(trifluoromethyl)benzoyl]amino]phenyl]pyrimidine-5-carboxamide
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|
C31H28F3N7O3
|
1
|
| 1 |
GI50 = 118 nM
|
|
|
|
CP0002778
|
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
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|
C29H31N7O
|
2
|
| 1 |
GI50 = 260 nM
|
|
|
| 2 |
GI50 > 10000 nM
|
|
|
|
CP0137907
|
2-(4-methylpiperazin-1-yl)-N-[4-methyl-5-[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]-1,3-thiazol-2-yl]acetamide
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|
C25H27N7OS
|
1
|
| 1 |
GI50 = 411.1 nM
|
|
|
|
CP0059308
|
1-[2-(3-aminophenyl)-5-tert-butylpyrazol-3-yl]-3-[4-(quinazolin-4-ylamino)phenyl]urea
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|
C28H28N8O
|
1
|
| 1 |
GI50 = 1600 nM
|
|
|
|
CP0387298
|
4-(methylamino)-2-[4-methyl-3-(propanoylamino)anilino]-N-[2-methyl-5-[(3,4,5-trimethoxybenzoyl)amino]phenyl]pyrimidine-5-carboxamide
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|
C33H37N7O6
|
1
|
| 1 |
GI50 = 2510 nM
|
|
|
|
CP0224766
|
4-(methylamino)-2-[4-methyl-3-(prop-2-enoylamino)anilino]-N-[2-methyl-5-[(3,4,5-trimethoxybenzoyl)amino]phenyl]pyrimidine-5-carboxamide
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|
C33H35N7O6
|
1
|
| 1 |
GI50 = 2560 nM
|
|
|
|
CP0096180
|
1-[5-tert-butyl-2-(3-nitrophenyl)pyrazol-3-yl]-3-[4-(quinazolin-4-ylamino)phenyl]urea
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|
C28H26N8O3
|
1
|
| 1 |
GI50 = 3500 nM
|
|
|
|
CP0019908
|
BDBM50242742
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|
C30H40ClN7O3S
|
1
|
| 1 |
IC50 = 1048 nM
|
|
|
|
CP0385508
|
2-[4-[4-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl]piperazin-1-yl]acetic acid
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|
C27H28FN7O2
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0388864
|
4-[6-(benzylamino)imidazo[1,2-b]pyridazin-3-yl]benzonitrile
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|
C20H15N5
|
1
|
| 1 |
IC50 = 3800 nM
|
|
|
|
CP0385511
|
1-[4-[6-[(2R)-2-(3-fluorophenyl)pyrrolidin-1-yl]imidazo[1,2-b]pyridazin-3-yl]pyridin-2-yl]piperidin-4-ol
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|
C26H27FN6O
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
