Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-(2-imidazo[1,5-b]pyridazin-7-ylethynyl)-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide
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 PubChem ID
CID: 155541742
Canonical SMILES
CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3ncc4cccnn34)cc2C(F)(F)F)CC1
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Compound Formula C29H27F3N6O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase ABL1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Abl family
Uniprot ID
P00519
Gene Name
ABL1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  2
1
GI50 < 1 nM
   TI
   LI
   LO
   TS
2
GI50 = 2 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 0.2 nM
   TI
   LI
   LO
   TS
2
IC50 = 4 nM
   TI
   LI
   LO
   TS
3
IC50 = 15 nM
   TI
   LI
   LO
   TS