| Compound ID |
Compound Name |
Compound Formula |
|
CP0302541
|
6-[5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-4-yl]-1,3-benzothiazole
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|
C14H10N4S2
|
1
|
| 1 |
IC50 = 8.7 nM
|
|
|
|
CP0335326
|
6-[2-methyl-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-4-yl]-1,3-benzothiazole
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|
C15H12N4S2
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0059959
|
N-[[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]butanamide
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|
C19H19N5OS2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0335325
|
6-[5-(4-methyl-1,3-thiazol-2-yl)-2-propyl-1H-imidazol-4-yl]-1,3-benzothiazole
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|
C17H16N4S2
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0110496
|
6-[2-ethyl-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-4-yl]-1,3-benzothiazole
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|
C16H14N4S2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0334943
|
ethyl N-[[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]carbamate
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|
C18H17N5O2S2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0335276
|
2-methylpropyl N-[[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]carbamate
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|
C20H21N5O2S2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0388939
|
propyl N-[[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]carbamate
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|
C19H19N5O2S2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0334942
|
methyl N-[[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]carbamate
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|
C17H15N5O2S2
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0192180
|
6-[2-cyclopentyl-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-4-yl]-1,3-benzothiazole
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|
C19H18N4S2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0449944
|
propan-2-yl N-[[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]carbamate
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|
C19H19N5O2S2
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0187438
|
1-[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]hexan-3-one
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|
C20H20N4OS2
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0110495
|
6-[2-(2-methylpropyl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-4-yl]-1,3-benzothiazole
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|
C18H18N4S2
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0110493
|
6-[2-cyclopropyl-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-4-yl]-1,3-benzothiazole
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|
C17H14N4S2
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0157864
|
6-[5-(4-methyl-1,3-thiazol-2-yl)-2-propan-2-yl-1H-imidazol-4-yl]-1,3-benzothiazole
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|
C17H16N4S2
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0310604
|
6-[5-(4-methyl-1,3-thiazol-2-yl)-2-(trifluoromethyl)-1H-imidazol-4-yl]-1,3-benzothiazole
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|
C15H9F3N4S2
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0259431
|
6-[2-tert-butyl-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-4-yl]-1,3-benzothiazole
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|
C18H18N4S2
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0170060
|
3-[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]-N-ethylpropanamide
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|
C19H19N5OS2
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0192179
|
N-[[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]butan-1-amine
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|
C19H21N5S2
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0110488
|
butyl N-[[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]carbamate
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|
C20H21N5O2S2
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0157778
|
6-[2-cyclohexyl-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-4-yl]-1,3-benzothiazole
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|
C20H20N4S2
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0284401
|
2,2-dimethylpropyl N-[[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]carbamate
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|
C21H23N5O2S2
|
1
|
| 1 |
IC50 = 79 nM
|
|
|
|
CP0259429
|
4-[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]cyclohexan-1-one
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|
C20H18N4OS2
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0192178
|
3-[[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]-1,3-oxazolidin-2-one
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|
C18H15N5O2S2
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0335324
|
[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl N-ethylcarbamate
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|
C18H17N5O2S2
|
1
|
| 1 |
IC50 = 93 nM
|
|
|
|
CP0545191
|
6-[5-(4-methyl-1,3-thiazol-2-yl)-2-(oxan-4-yl)-1H-imidazol-4-yl]-1,3-benzothiazole
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|
C19H18N4OS2
|
1
|
| 1 |
IC50 = 99 nM
|
|
|
|
CP0334944
|
N-[[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]-N-methylbutanamide
Show/Hide
|
C20H21N5OS2
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0192181
|
6-[2-hexyl-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-4-yl]-1,3-benzothiazole
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|
C20H22N4S2
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0187435
|
N-[2-[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]ethyl]propanamide
Show/Hide
|
C19H19N5OS2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0207963
|
1-[[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]-3-ethylurea
Show/Hide
|
C18H18N6OS2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0207965
|
1-[[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]pyrrolidin-2-one
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|
C19H17N5OS2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0453685
|
pentyl N-[[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]carbamate
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|
C21H23N5O2S2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0284402
|
N-[[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]propane-1-sulfonamide
Show/Hide
|
C18H19N5O2S3
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0404915
|
N-[3-[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]propyl]acetamide
Show/Hide
|
C19H19N5OS2
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0200896
|
4-[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]benzamide
Show/Hide
|
C21H16N4O3S
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0310603
|
5-[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]pentanamide
Show/Hide
|
C19H19N5OS2
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0110491
|
4-[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]-N-methylbutanamide
Show/Hide
|
C19H19N5OS2
|
1
|
| 1 |
IC50 = 230 nM
|
|
|
|
CP0106272
|
4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-amine
Show/Hide
|
C14H12N4O2S
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0282937
|
N-[[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]butanamide
Show/Hide
|
C19H20N4O3S
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0282935
|
4-[4-(1,3-benzodioxol-5-yl)-5-(4-bromo-1,3-thiazol-2-yl)-1H-imidazol-2-yl]benzamide
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|
C20H13BrN4O3S
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0284403
|
4-(1,3-benzothiazol-6-yl)-N-butyl-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazole-2-carboxamide
Show/Hide
|
C19H19N5OS2
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0282936
|
N-[[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]benzamide
Show/Hide
|
C22H18N4O3S
|
1
|
| 1 |
IC50 = 680 nM
|
|
|
|
CP0290751
|
4-[4-(1,3-benzodioxol-5-yl)-5-(2-methyl-1,3-thiazol-4-yl)-1H-imidazol-2-yl]benzamide
Show/Hide
|
C21H16N4O3S
|
1
|
| 1 |
IC50 = 680 nM
|
|
|
|
CP0290754
|
5-[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]pentanamide
Show/Hide
|
C19H20N4O3S
|
1
|
| 1 |
IC50 = 730 nM
|
|
|
|
CP0164749
|
5-[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]-N-propylpentanamide
Show/Hide
|
C22H26N4O3S
|
1
|
| 1 |
IC50 = 750 nM
|
|
|
|
CP0322876
|
4-[4-(1,3-benzodioxol-5-yl)-5-(4-ethyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]benzamide
Show/Hide
|
C22H18N4O3S
|
1
|
| 1 |
IC50 = 760 nM
|
|
|
|
CP0095008
|
5-[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]-N-phenylpentanamide
Show/Hide
|
C25H24N4O3S
|
1
|
| 1 |
IC50 = 830 nM
|
|
|
|
CP0095006
|
3-[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]propan-1-amine
Show/Hide
|
C17H18N4O2S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0290753
|
3-[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]-N-propylpropanamide
Show/Hide
|
C20H22N4O3S
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0200898
|
N-[[4-(4-hydroxyphenyl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]butanamide
Show/Hide
|
C18H20N4O2S
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0079582
|
N-[3-[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]propyl]butanamide
Show/Hide
|
C21H24N4O3S
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0079581
|
N-[2-[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]ethyl]butanamide
Show/Hide
|
C20H22N4O3S
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0095007
|
4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-N-phenyl-1H-imidazole-2-carboxamide
Show/Hide
|
C21H16N4O3S
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0322880
|
4-[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]-N-propylbutanamide
Show/Hide
|
C21H24N4O3S
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0099722
|
2-[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]ethanamine
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|
C16H16N4O2S
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0248371
|
N-[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]acetamide
Show/Hide
|
C16H14N4O3S
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0275137
|
N-[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]butanamide
Show/Hide
|
C18H18N4O3S
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0282934
|
4-[4-(1,3-benzodioxol-5-yl)-5-(1,3-thiazol-2-yl)-1H-imidazol-2-yl]benzamide
Show/Hide
|
C20H14N4O3S
|
1
|
| 1 |
IC50 = 2700 nM
|
|
|
|
CP0322877
|
[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methanamine
Show/Hide
|
C15H14N4O2S
|
1
|
| 1 |
IC50 = 3600 nM
|
|
|
|
CP0248370
|
4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-N-propyl-1H-imidazole-2-carboxamide
Show/Hide
|
C18H18N4O3S
|
1
|
| 1 |
IC50 = 3900 nM
|
|
|
|
CP0290755
|
N-[[4-(4-fluorophenyl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]butanamide
Show/Hide
|
C18H19FN4OS
|
1
|
| 1 |
IC50 = 6400 nM
|
|
|
