Brief Information of the Compound and Protein
Compound Name
3-[[4-(1,3-benzothiazol-6-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]-1,3-oxazolidin-2-one
    Show/Hide
PubChem ID
CID: 135442675
SID: 16417019
Canonical SMILES
Cc1csc(n1)-c1[nH]c(CN2CCOC2=O)nc1-c1ccc2ncsc2c1
    Show/Hide
Compound Formula C18H15N5O2S2
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  1
1
IC50 = 92 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 8.1 nM