Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]-N-propylbutanamide
    Show/Hide
 PubChem ID
CID: 136042370
Canonical SMILES
CCCNC(=O)CCCc1nc(c([nH]1)-c1nc(C)cs1)-c1ccc2OCOc2c1
    Show/Hide
Compound Formula C21H24N4O3S
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1700 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 510 nM