Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[[4-(1,3-benzodioxol-5-yl)-5-(4-methyl-1,3-thiazol-2-yl)-1H-imidazol-2-yl]methyl]benzamide
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 PubChem ID
CID: 136042363
Canonical SMILES
Cc1csc(n1)-c1nc(CNC(=O)c2ccccc2)[nH]c1-c1ccc2OCOc2c1
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Compound Formula C22H18N4O3S
Compound Structure
Protein Name
 Protein Info 
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 680 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 150 nM