| Compound ID |
Compound Name |
Compound Formula |
|
CP0579400
|
7-methyl-2-[(7-methylquinolin-6-yl)amino]-9-(oxan-4-yl)purin-8-one
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|
C21H22N6O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0577945
|
7-methyl-2-[(7-methylquinazolin-6-yl)amino]-9-(oxan-4-yl)purin-8-one
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|
C20H21N7O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0552015
|
7-methyl-2-[(7-methylcinnolin-6-yl)amino]-9-(oxan-4-yl)purin-8-one
Show/Hide
|
C20H21N7O2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0571788
|
7-methyl-2-[(7-methylquinoxalin-6-yl)amino]-9-(oxan-4-yl)purin-8-one
Show/Hide
|
C20H21N7O2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0562043
|
9-cyclohexyl-7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-7,9-dihydro-8H-purin-8-one
Show/Hide
|
C19H22N8O
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
|
CP0533756
|
9-(4-hydroxycyclohexyl)-2-(4-methoxy-2-methylanilino)-7-methylpurin-8-one
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|
C20H25N5O3
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0571631
|
7-methyl-2-[(7-methylquinolin-6-yl)amino]-9-[(3S)-1-(oxetan-3-yl)pyrrolidin-3-yl]purin-8-one
Show/Hide
|
C23H25N7O2
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0418436
|
7-methyl-2-[(7-methylimidazo[1,2-a]pyridin-6-yl)amino]-9-(oxan-4-yl)purin-8-one
Show/Hide
|
C19H21N7O2
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0422671
|
9-(4,4-difluorocyclohexyl)-7-methyl-2-[(7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]purin-8-one
Show/Hide
|
C19H20F2N8O
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0574338
|
9-((1r,4r)-4-hydroxycyclohexyl)-7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-7,9-dihydro-8H-purin-8-one
Show/Hide
|
C19H22N8O2
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0528088
|
9-((1s,4s)-4-hydroxy-4-methylcyclohexyl)-7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-7,9-dihydro-8H-purin-8-one
Show/Hide
|
C20H24N8O2
|
1
|
| 1 |
IC50 = 63.1 nM
|
|
|
|
CP0473312
|
7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-9-(tetrahydro-2H-pyran-4-yl)-7,9-dihydro-8H-purin-8-one
Show/Hide
|
C18H20N8O2
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0571632
|
7-methyl-9-(1-methylpiperidin-4-yl)-2-[(7-methylquinoxalin-6-yl)amino]purin-8-one
Show/Hide
|
C21H24N8O
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
|
CP0426118
|
9-(4-hydroxycyclohexyl)-2-(5-methoxy-2-methylanilino)-7-methylpurin-8-one
Show/Hide
|
C20H25N5O3
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0559875
|
9-((1r,4r)-4-hydroxy-4-methylcyclohexyl)-7-methyl-2-((7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino)-7,9-dihydro-8H-purin-8-one
Show/Hide
|
C20H24N8O2
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0552016
|
9-[(3R,4R)-4-fluoro-1-methylpyrrolidin-3-yl]-7-methyl-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
|
C21H22FN7O
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0579887
|
9-[(3S)-1-(2-methoxyethyl)pyrrolidin-3-yl]-7-methyl-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
|
C23H27N7O2
|
1
|
| 1 |
IC50 = 129 nM
|
|
|
|
CP0571634
|
9-[(3R,4R)-4-fluoropyrrolidin-3-yl]-7-methyl-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
|
C20H20FN7O
|
1
|
| 1 |
IC50 = 134 nM
|
|
|
|
CP0579976
|
9-[(3S)-1-(2-hydroxyethyl)pyrrolidin-3-yl]-7-methyl-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
|
C22H25N7O2
|
1
|
| 1 |
IC50 = 142 nM
|
|
|
|
CP0559874
|
CHEMBL4459057
Show/Hide
|
C19H23N5O3
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0577525
|
9-[(3R,4S)-4-fluoro-1-methylpyrrolidin-3-yl]-7-methyl-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
|
C21H22FN7O
|
1
|
| 1 |
IC50 = 203 nM
|
|
|
|
CP0550188
|
7-methyl-9-(1-methylpiperidin-4-yl)-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
|
C22H25N7O
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0426117
|
9-(4-hydroxycyclohexyl)-7-methyl-2-(2-methylanilino)purin-8-one
Show/Hide
|
C19H23N5O2
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0540877
|
9-(4-hydroxycyclohexyl)-7-methyl-2-[(7-methylimidazo[1,2-a]pyridin-6-yl)amino]purin-8-one
Show/Hide
|
C20H23N7O2
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0530066
|
9-cyclopentyl-2-(4-methoxy-2-methylanilino)-7-methylpurin-8-one
Show/Hide
|
C19H23N5O2
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0571633
|
7-methyl-2-[(7-methylquinolin-6-yl)amino]-9-piperidin-4-ylpurin-8-one
Show/Hide
|
C21H23N7O
|
1
|
| 1 |
IC50 = 335 nM
|
|
|
|
CP0579065
|
7-methyl-9-[(3S)-1-methylpyrrolidin-3-yl]-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
|
C21H23N7O
|
1
|
| 1 |
IC50 = 336 nM
|
|
|
|
CP0488066
|
9-cyclohexyl-2-(4-methoxy-2-methylanilino)-7-methylpurin-8-one
Show/Hide
|
C20H25N5O2
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0569061
|
7-methyl-9-[(3R)-1-methylpyrrolidin-3-yl]-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
|
C21H23N7O
|
1
|
| 1 |
IC50 = 608 nM
|
|
|
|
CP0579416
|
9-[(3R,4S)-4-fluoropyrrolidin-3-yl]-7-methyl-2-[(7-methylquinolin-6-yl)amino]purin-8-one
Show/Hide
|
C20H20FN7O
|
1
|
| 1 |
IC50 = 1056 nM
|
|
|
|
CP0543615
|
7-methyl-9-(1-methylpiperidin-4-yl)-2-[(7-methyl-[1,2,4]triazolo[1,5-a]pyridin-6-yl)amino]purin-8-one
Show/Hide
|
C19H23N9O
|
1
|
| 1 |
IC50 = 1164 nM
|
|
|
|
CP0566608
|
9-(4-hydroxycyclohexyl)-2-(4-methoxyanilino)-7-methylpurin-8-one
Show/Hide
|
C19H23N5O3
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0418435
|
CHEMBL4529390
Show/Hide
|
C20H23N7O2
|
1
|
| 1 |
IC50 = 1995.26 nM
|
|
|
|
CP0578239
|
7-methyl-2-[(7-methylcinnolin-6-yl)amino]-9-(1-methylpiperidin-4-yl)purin-8-one
Show/Hide
|
C21H24N8O
|
1
|
| 1 |
IC50 = 2088 nM
|
|
|
|
CP0540878
|
CHEMBL4456514
Show/Hide
|
C18H21N5O2
|
1
|
| 1 |
IC50 = 5011.87 nM
|
|
|
